Results 81 to 90 of about 1,707,874 (288)

Cinematic rendering for three-dimensional reconstructions of the chest wall: a new reality

Einstein (São Paulo), 2020
Computed tomography with multiple detectors and the advancement of processors improved rendered images and three-dimensional reconstructions in clinical practice. Traditional axial slices form non-intuitive images because they are seen in only one plane.
Altair da Silva Costa Jr., Norman Gellada   +1 more
doaj   +2 more sources

Progress in Three-Dimensional Coherent X-Ray Diffraction Imaging [PDF]

, 2005
The Fourier inversion of phased coherent diffraction patterns offers images without the resolution and depth-of-focus limitations of lens-based tomographic systems.
Barty, A., Beetz, T., Chapman, H. N., Cui, C., Hau-Riege, S. P., He, H., Howells, M. R., Jacobsen, C., Kinney, J. M., Lima, E., Marchesini, S., Minor, A. M., Noy, A., Rosen, R., Shapiro, D., Spence, J. C. H., Weierstall, U.   +16 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Skeletonization algorithm FOR OBJECTS ON THREE-DIMENSIONAL RASTER IMAGES

Доклады Белорусского государственного университета информатики и радиоэлектроники, 2019
A skeleton building algorithm in case of lack of memory is presented. Built skeleton is topologically equivalent to the original object. Despite the fact that data are processed locally, this algorithm preserves a skeleton global attribute - centeredness.
D. A. Goncharov, A. M. Nedzved, S. V. Ablameyko   +2 more
doaj  

Anisotropic nano-scale resolution in 3D Bragg coherent diffraction imaging

, 2018
We demonstrate that the resolution of three-dimensional (3D) real-space images obtained from Bragg x-ray coherent diffraction measurements is direction dependent.
Cha, Wonsuk, Cherukara, Mathew J., Harder, Ross J.   +2 more
core   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Using restored two-dimensional X-ray images to reconstruct the three-dimensional magnetopause

Earth and Planetary Physics
Astronomical imaging technologies are basic tools for the exploration of the universe, providing basic data for the research of astronomy and space physics.
RongCong Wang, JiaQi Wang, DaLin Li, TianRan Sun, XiaoDong Peng, YiHong Guo   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source