Results 61 to 70 of about 24,812,873 (248)

A Novel Three-Dimensional Wound Healing Model

Journal of Developmental Biology, 2014
Wound healing is a well-orchestrated process, with various cells and growth factors coming into the wound bed at a specific time to influence the healing. Understanding the wound healing process is essential to generating wound healing products that help
Zhuo J. Chen, Jessica P. Yang, Benjamin M. Wu, Bill Tawil   +3 more
doaj   +1 more source

Epigenetic reprogramming of lineage switching in cancer

FEBS Letters, EarlyView.
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı, Burcu Akman, Ezgi Bağırsakçı, Nese Atabey, Serap Erkek‐Ozhan   +4 more
wiley   +1 more source

Instability Criterion of One-Dimensional Detonation Wave with Three-Step Chain Branching Reaction Model [PDF]

, 2011
One-dimensional detonation waves are simulated with the three-step chain branching reaction model, and the instability criterion is studied. The ratio of the induction zone length and the reaction zone length may be used to decide the instability, and ...
姜宗林, 滕宏辉, Teng, HH (reprint author), Chinese Acad Sci, Inst Mech, Key Lab High Temp Gas Dynam, Beijing 100190, Peoples R China   +2 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Application of three-dimensional printing teaching model in knee surgery

Asian Journal of Surgery, 2021
Zhao Bin, Yao Shuzhang, Zhao Xuequan
doaj   +1 more source

The many dimensions of the digital model

Agathón, 2020
In the construction of a model, architectural drawing is not so much ‘representative drawing’ as ‘constructive drawing’. Scale and measure are fundamental criteria for interpreting and representing the parts of a unicum linked together in a hierarchical ...
Francesca Fatta
doaj   +1 more source

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Comparison of reliability, validity, and accuracy of linear measurements made on pre- and posttreatment digital study models with conventional plaster study models

Journal of Orthodontic Science, 2019
OBJECTIVES: To compare the accuracy of the linear measurements made on pre- and posttreatment three-dimensional (3D) scanned digital models with conventional plaster study models.
Raj Kumar Verma, Satinder Pal Singh, Sanjeev Verma, Vinay Kumar, Nameksh Raj Bhupali, Sohail Arora   +5 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

CFD Analysis and Experimental Study on the Effect of Geometries for the Performance of an Ejector

Zhileng xuebao, 2014
The ejector performance is numerically and experimentally investigated using R236fa as working fluid to analyze the influence of the critical geometries of ejector.
Xia Zaichao, Li Jianxin, Gao De, Chen Guangming   +3 more
doaj