Results 71 to 80 of about 24,812,873 (248)

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Translating in silico micro-computed tomography bone scans into a 3D printable bone model

Frontiers in Bioengineering and Biotechnology
Personalised medicine is an expanding area of medical research, in which patient-specific physiology informs clinical interventions. The personalisation of skeletal-based medical implants through 3D imaging and additive manufacturing (AM) has the ...
Lucy Dascombe, David A. Chorlton, Tim Nichol, Christine L. Le Maitre, Nicola Aberdein   +4 more
doaj   +1 more source

Extreme-Point-based Heuristics for the Three-Dimensional Bin Packing problem [PDF]

, 2008
One of the main issues in addressing three-dimensional packing problems is finding an efficient and accurate definition of the points at which to place the items inside the bins, because the performance of exact and heuristic solution methods is actually
CRAINIC T. G, Crainic T.G, Perboli, Guido, Tadei, Roberto   +3 more
core   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

THREE-DIMENSIONAL MODEL OF A HIP PROSTHESIS

Journal of Industrial Design and Engineering Graphics, 2019
Serious pathological problems of the hip joint can be solved surgically, in some cases by joint prosthesis. For this reason, it is very important to be able to shape, in a first phase, the components of the prosthesis, which can then be tested virtually.
Razvan Cristian Vaduva, Ilaria Loredana Petrovici, Mihai Catalin Tenovici, Danut Nicolae Tarnita, Dragos Laurentiu Popa, Daniel Cosmin Calin, Otilia Rogoveanu   +6 more
doaj   +4 more sources

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source

An Energy Model of Place Cell Network in Three Dimensional Space

Frontiers in Neuroscience, 2018
Place cells are important elements in the spatial representation system of the brain. A considerable amount of experimental data and classical models are achieved in this area. However, an important question has not been addressed, which is how the three
Yihong Wang, Xuying Xu, Rubin Wang
doaj   +1 more source

Three-dimensional road model of slope-curve section of TruckSim.

, 2021
Three-dimensional road model of slope-curve section of TruckSim.
Yanfei Li (3413285), Lin Tian (134035), Jueshuai Li (11302034), Wenzhen Lv (1765876)   +3 more
core   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source