Results 41 to 50 of about 3,186,854 (184)

On the deformation theory of structure constants for associative algebras [PDF]

, 2009
Algebraic scheme for constructing deformations of structure constants for associative algebras generated by a deformation driving algebras (DDAs) is discussed. An ideal of left divisors of zero plays a central role in this construction.
Konopelchenko, B. G.
core   +5 more sources

Evaluation of in vitro toxicity of common phytochemicals included in weight loss supplements using 1H NMR spectroscopy

FEBS Open Bio, EarlyView.
We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies, Garth L. Maker, Ian F. Musgrave, Samantha Lodge   +3 more
wiley   +1 more source

Pioglitazone plus (−)‐epigallocatechin gallate: a novel approach to enhance osteogenic performance in aged bone marrow mesenchymal stem cells

FEBS Open Bio, EarlyView.
Aged human bmMSCs are seeded in the scaffold. Osteoblastic induction can slightly increase cell's bone‐forming activity to produce bone‐like tissues, shown as the sporadic xylenol orange‐stained spots (the lower left image). Notably, pioglitazone plus EGCG co‐treatment dramatically increases cell's bone‐forming activity and bone‐like tissue production (
Ching‐Yun Chen, Jia‐Ci Jhang, Chun‐Yi Peng, Quốc Cường Nguyễn, Feng‐Huei Lin, Hung‐Ming Wu, Shankung Lin   +6 more
wiley   +1 more source

Phase Structure and Nonperturbative States in Three-Dimensional Adjoint Higgs Model

, 1997
The thermodynamics of 3d adjoint Higgs model is considered. We study the properties of the Polyakov loop correlators and the critical behavior at the deconfinement phase transition. Our main tool is a reduction to the 2d sine-Gordon model.
A. B. Zamolodchikov, A. Hart, A. M. Polyakov, A. M. Polyakov, A. M. Polyakov, A. M. Polyakov, Al. B. Zamolodchikov, B. Svetitsky, B. Svetitsky, D. A. Kirzhnitz, D. A. Kirzhnitz, E. B. Bogomolny, G. ’t Hooft, J. I. Kapusta, J. K. Perring, J. M. Kosterlitz, J. V. José, K. Zarembo, M. K. Prasad, N. J. Snyderman, N. O. Agasyan, R. F Dashen, S. Coleman, S. Mandelstam, S. R. Das, T. H. R. Skyrme, T. W. Kirkman, V. E. Korepin, V. G. Kiselev   +28 more
core   +2 more sources

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

N=2 supergravity in three dimensions and its Godel supersymmetric background

, 2007
The four dimensional Godel spacetime is known to have the structure M_3 x R. It is also known that the three-dimensional factor M_3 is an exact solution of three-dimensional gravity coupled to a Maxwell-Chern-Simons theory.
Banados, Maximo, Faraggi, Alberto T., Theisen, Stefan   +2 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Anchorage‐independent and faster growth in clonal population from UV‐irradiated NER‐deficient cells

FEBS Open Bio, EarlyView.
UV‐irradiated cells expressing a DDB2 mutant protein unable to interact with PCNA (DDB2PCNA‐) form clones able to grow without anchorage. Different experimental approaches reveal heterogeneity in cell cycle regulation and drug response within these clones, emphasizing the crucial role of the DDB2‐PCNA interaction in preventing cellular transformation ...
Paola Perucca, Anna Tricarico, Martina Furfaro, Priyam Ghosh, Ennio Prosperi, Lucia Anna Stivala, Ornella Cazzalini   +6 more
wiley   +1 more source

On the Dynamics and Structure of Three-Dimensional Trans-Alfvenic Jets

, 1999
Three-dimensional magnetohydrodynamical simulations of strongly magnetized ``light'' conical jets have been performed. An investigation of the transition from sub-Alfv\'enic to super-Alfv\'enic flow has been made for nearly poloidal and for helical ...
Alexander Rosen, Appl S., Bodo G., Ferrari A., Ouyed R., Philip E. Hardee, Ray T. P.   +6 more
core   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source