Results 21 to 30 of about 125,818 (246)

Fatigue Precracking Time Estimates for Three-Point Bending Specimens

open access: yesJournal of Failure Analysis and Prevention, 2019
Specimens containing sharp cracks are needed in certain types of mechanical tests, first and foremost for fracture toughness measurement of materials. Their use, however, is not just limited to this type of test. Another category of experiments deals with characterizing nonlinear vibrations of beams containing breathing cracks.
A. Alipour Ghasabi   +2 more
openaire   +2 more sources

Study on Thickness Effect of Three-Point-Bend Specimen

open access: yesJSME International Journal Series A, 2004
The thickness effect of three point bend (3 PB) specimen on dimple fracture behavior is studied experimentally and numerically. At first, fracture toughness tests were conducted using 3 PB specimens with different thicknesses. Fracture toughness values and R-curves are obtained and the thickness effect is discussed.
Masanori KIKUCHI, Takehito ISHIHARA
openaire   +3 more sources

Natural plant stems modelling in a three-point bending test

open access: yesMATEC Web of Conferences, 2019
The paper presents an approach to natural plant stems numerical modelling in a three-point bending test. Introduced subject was connected with elaborating more efficient systems for harvesting energetic plants.
Kawecki Bartosz   +2 more
doaj   +1 more source

Mechanical Characteristics and Energy Evolution of Sandstone Three-Point Bending Test

open access: yesShock and Vibration, 2021
With the increase of underground mining depth in coal mines, the distribution of stress fields in deep mining becomes more complex, and the stress localization characteristics are obvious.
Tao Qin   +4 more
doaj   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Numerical Study of Bending Behavior for 66 kV Submarine Cables

open access: yes한국해양공학회지
Submarine cables operate in complex marine environments and are repeatedly subjected to lateral loads from ocean currents, waves, and seabed irregularities.
YunJae Kim   +4 more
doaj   +1 more source

Bone Fracture Modeling and Analysis by Three Point Bending: A Review

open access: yesMATEC Web of Conferences, 2016
Bones are the main structural components of a skeleton in our body. They run as a special role in the body providing its shape maintenance, protection of internal organs and transmission of forces.
Salim Mohammad Shahril   +2 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

Mechanism study of brittle-to-ductile transition temperature in W-0.2 wt% Al2O3 alloy

open access: yesJournal of Materials Research and Technology
W-0.2 wt% Al2O3 alloy plates were fabricated using composite powders prepared by the wet chemical method, followed by cold isostatic pressing, vacuum sintering, and hot-rolling.
Ziwen Zhao   +9 more
doaj   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

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