Results 91 to 100 of about 3,059 (280)

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

The Three Seas Initiative and its Economic and Geopolitical Effect on the European Union and Central and Eastern Europe

Comparative Economic Research, 2019
The objective of this paper is a presentation of results of an analysis of the Three Seas Initiative (TSI), whose participating countries (except Austria) treat it as a method of: a) reducing their dependence on crude oil and natural gas imports from ...
Grzegorz Zbińkowski
doaj   +1 more source

Slovakia and the Three Seas Initiative

Studia Polityczne
Although Slovakia is one of the founding countries of the Three Seas Initiative (TSI), from the beginning it expressed numerous doubts about the added value of the initiative. This resulted in an often low level of representation at TSI summits and no contribution to the TSI Investment Fund. The motive for this approach is the fear that the project has
openaire   +1 more source

The ubiquitin‐proteasome system and autophagy as guardians of the cellular proteome

FEBS Letters, EarlyView.
This Perspective covers the three principles governing the crosstalk between the ubiquitin‐proteasome system and autophagy in cellular proteostasis: (1) a shared ubiquitin code routing substrates via shuttle factors or autophagy receptors; (2) spatial compartmentalization into phase‐separated degradation hubs and organelle‐specific modules (exemplified
Ivan Dikic
wiley   +1 more source

Intermarium, Three Seas Initiative (Trimarium), or Mitteleuropa? In Search of Poland’s Place in Central Europe

, 2023
The author discusses the uniqueness and idiosyncrasies of Central European history, wondering what is there for the contemporary Polish state to do in a region threatened by Russian expansionist policies. Three distinct ways of shaping Polish foreign and
Brzechczyn, Krzysztof
core  

Cell geometry and membrane protein crowding constrain Escherichia coli growth rate, overflow metabolism, respiration, and maintenance energy

FEBS Letters, EarlyView.
The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson, Tomáš Gedeon, Mauricio Garcia Benitez, Campbell Putnam, William R. Harcombe, Radhakrishnan Mahadevan, Ashley E. Beck   +6 more
wiley   +1 more source

The Three Seas Initiative in the Bulgarian security policy

, 2018
W artykule zaprezentowano regionalny wymiar bułgarskiej polityki bezpieczeństwa. Dokonano tego w oparciu o nowopowstałą Inicjatywę Trójmorza. Zaprezentowano priorytety bułgarskiej polityki bezpieczeństwa w ramach tej inicjatywy, ale także w ramach ...
Czernicka, Marzena
core  

Electron transfer between complexes III and IV in S. cerevisiae mitochondrial membranes

FEBS Letters, EarlyView.
Mitochondrial oxidative phosphorylation in S. cerevisiae mitoplasts is limited by complex IV catalytic capacity, rather than two‐dimensional cytochrome c diffusion. At physiological cytochrome c : supercomplex ratios at salinity equivalent to that of 20 mm monovalent salt, activity is maximized, indicating that this low ionic strength accurately mimics
Ana Paula Lobez, Mikael Oliveberg, Peter Brzezinski   +2 more
wiley   +1 more source

The Three Seas Initiative in the foreign affairs policy of Hungary

Rocznik Instytutu Europy Środkowo-Wschodniej, 2019
The Three Seas Initiative (TSI) constitutes a project involving the cooperation of twelve European countries. Poland and Croatia, the founders of the TSI, are especially active in this respect. Even though Hungary seems the closest political ally of Poland, the country rarely participates in TSI actions. In addition, when pursuing its politics, Hungary
openaire   +1 more source

Principles of access to financial resources of the Three Seas Initiative countries

Ius et Administratio, 2023
According to the adopted title, the subject of considerations is to indicate the statutory rules regarding the acquisition of financial resources by the countries included in the area of Three Seas Initiative (TSI). Due to the adopted topic, the axiology of the Three Seas Initiative term will be clarified showing the genesis of its origin.More ...
openaire   +1 more source