Results 91 to 100 of about 12,161,773 (274)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Three Seas Initiative in the foreign affairs policy of Hungary
Rocznik Instytutu Europy Środkowo-Wschodniej, 2019 The Three Seas Initiative (TSI) constitutes a project involving the cooperation of twelve European countries. Poland and Croatia, the founders of the TSI, are especially active in this respect. Even though Hungary seems the closest political ally of Poland, the country rarely participates in TSI actions. In addition, when pursuing its politics, Hungary
openaire +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
The Three Seas Initiative: Geopolitical Determinants and a New Model of Regional Cooperation [PDF]
, 2018 The objective of the present paper is to discuss the Three Seas Initiative (TSI) as a project in statu nascendi. The TSI aims to tighten the cooperation of states located between the Baltic, the Black, and the Adriatic seas.
Stępniewski, Tomasz
core
, 2021 Stable Seas, a program of One Earth Future, works with militaries, governments, and other partners around the world to eliminate the maritime activities that finance and facilitate organized political violence.
Stable Seas
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Annals of the "Ovidius" University of Constanţa. Political Science Series, 2022 The minilateral format is not an unknown concept in Romania’s geopolitical strategy. From regional initiatives based on the principle of interwar collective security to the Bucharest Nine format, Romania has participated but also initiated regional
Octavian Popa
doaj
An Attempt to Systematically Revisit the Process of Conceptualization and Political Maturation of the Three Seas Initiative (3SI) [PDF]
Analele Universităţii din Oradea. Relaţii Internaţionale şi Studii EuropeneThe main purpose of the study is to provide an informed and contextually relevant view of the Three Seas Initiative (3SI), which adds to the geographical and thematic cooperation formats already in place in the European Union (EU).
Andrea AMZA-ANDRÁS
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source