Results 101 to 110 of about 12,161,773 (274)
The Three Seas Initiative in Poland’s Foreign Policy [PDF]
, 2018 The purpose of this article is to analyse activities of the new regional grouping in the Central Europe – the Three Seas Initiative. The research covered the declared and factual goals, with particular emphasis on the question to what extent the project ...
Ukielski, Paweł
core
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Central European Direction of U.S. Foreign Policy: from Velvet Revolutions to Ukrainian Crisis [PDF]
Современная ЕвропаThe article analyses the historical and political development of Central Europe since the Velvet Revolutions of the late 1980s to the present day. The study demonstrated that after the collapse of the socialist regimes, Washington began to pay close ...
Mikhail Vedernikov
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Evolution of Germany’s Stance Regarding the Three Seas Initiative
Rocznik Instytutu Europy Środkowo-Wschodniej, 2019 When the political camp centred on the Law and Justice party (PiS) came to power in 2015, it led to a change in priorities in Polish foreign policy. The Three Seas Initiative (TSI), understood as closer cooperation between eastern states of the European Union in the area between the Baltic, Adriatic, and Black seas, has become a new instrument of ...
openaire +1 more source
A THREE SEAS VIEW OF THE UNITED NATIONS – THE POTENTIAL IMPORTANCE OF THE THREE SEAS INITIATIVE FOR IMPLEMENTATION OF THE SUSTAINABLE DEVELOPMENT GOALS AND RELATED INSTRUMENTS OF INTERNATIONAL COOPERATION [PDF]
In 2015, on the sidelines of the 70th General Assembly of the United Nations (UN), the Three Seas Initiative (3SI) was established. It is a format of economic cooperation between 13 countries in Central, North- and South-Eastern Europe that are the ...
Wójcik, Piotr
core +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The paper analyses the role of strategic international investments in strengthening economic resilience in Central and Eastern Europe, with a focus on the Three Seas Initiative as a regional development tool. In the context of geopolitical uncertainties,
Andrei Eduard DICA, Gheorghe HURDUZEU
core +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
FEBS Letters, EarlyView.EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source