Results 101 to 110 of about 3,059 (280)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
The Three Seas Initiative: Geopolitical Determinants and a New Model of Regional Cooperation
, 2018 The objective of the present paper is to discuss the Three Seas Initiative (TSI) as a project in statu nascendi. The TSI aims to tighten the cooperation of states located between the Baltic, the Black, and the Adriatic seas.
Stępniewski, Tomasz
core
FEBS Letters, EarlyView.Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara +3 more
wiley +1 more source
Annals of the "Ovidius" University of Constanţa. Political Science Series, 2022 The minilateral format is not an unknown concept in Romania’s geopolitical strategy. From regional initiatives based on the principle of interwar collective security to the Bucharest Nine format, Romania has participated but also initiated regional
Octavian Popa
doaj
An Attempt to Systematically Revisit the Process of Conceptualization and Political Maturation of the Three Seas Initiative (3SI) [PDF]
Analele Universităţii din Oradea. Relaţii Internaţionale şi Studii EuropeneThe main purpose of the study is to provide an informed and contextually relevant view of the Three Seas Initiative (3SI), which adds to the geographical and thematic cooperation formats already in place in the European Union (EU).
Andrea AMZA-ANDRÁS
doaj +1 more source
FEBS Letters, EarlyView.Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley +1 more source
The Three Seas Initiative in Poland’s Foreign Policy
, 2018 The purpose of this article is to analyse activities of the new regional grouping in the Central Europe – the Three Seas Initiative. The research covered the declared and factual goals, with particular emphasis on the question to what extent the project ...
Ukielski, Paweł
core
In 2015, on the sidelines of the 70th General Assembly of the United Nations (UN), the Three Seas Initiative (3SI) was established. It is a format of economic cooperation between 13 countries in Central, North- and South-Eastern Europe that are the ...
Wójcik, Piotr
core +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source