Results 181 to 190 of about 518,828 (334)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

open access: yesAdvanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu   +9 more
wiley   +1 more source

Direct and Low‐Temperature Regeneration of Degraded LiFePO₄ Cathodes at Ambient Conditions Using Green and Sustainable Deep Eutectic Solvent

open access: yesAdvanced Science, Volume 12, Issue 28, July 24, 2025.
Computational predictions identify ethylene glycol and lithium chloride as optimal components for a green deep eutectic solvent (DES). And further investigations determine the optimal reaction conditions and process parameters for DES treatment of spent lithium iron phosphate (S‐LFP).
Yixin Lin   +7 more
wiley   +1 more source

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

open access: yesAdvanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong   +15 more
wiley   +1 more source

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