Results 11 to 20 of about 535,642 (304)

Botulinum toxin for the treatment of lower limb cramp pain in patients with Amyotrophic Lateral Sclerosis [PDF]

open access: yes, 2020
Background: Muscle cramps and pain associated with them can be seen in patients with amyotrophic lateral sclerosis (ALS) and are known to reduce the quality of life. Pharmacological treatment may not benefit all patients in treating these cramps.
Govindarajan, Raghav   +2 more
core   +2 more sources

Methylmalonic Aciduria in Children: Clinical Recommendations

open access: yesПедиатрическая фармакология, 2017
Methylmalonic acidemia (aciduria) is an inherited metabolic disturbance from the group of organic acidemias (acidurias). The article presents etiopathogenetic, epidemiological, diagnostic, and therapeutic aspects of the problem.
Alexander A. Baranov   +16 more
doaj   +1 more source

Dietary Supplementation with Lysine and Threonine Modulates the Performance and Plasma Metabolites of Broiler Chicken

open access: yesThe Journal of Poultry Science, 2019
Here, we investigated whether the optimal threonine (Thr) to lysine (Lys) ratio in high Lys diet improves the growth performance of modern broiler chickens at finisher period and determined the possible mechanism underlying improvement in the growth ...
Toshiyuki Ishii   +6 more
doaj   +1 more source

Effects of low-crude protein diets supplemented with arginine, glutamine, threonine, and methionine on regulating nutrient absorption, intestinal health, and growth performance of Eimeria-infected chickens

open access: yesPoultry Science, 2021
: The study was conducted to evaluate the effects of low crude protein diets supplemented with arginine, glutamine, methionine, and/or threonine on apparent ileal digestibility of amino acids, intestinal morphology, intestinal permeability, gene ...
Po-Yun Teng   +4 more
doaj   +1 more source

Skotomorphogenesis exploits threonine to promote hypocotyl elongation

open access: yesQuantitative Plant Biology, 2022
Mobilisation of seed storage reserves is important for seedling establishment in Arabidopsis. In this process, sucrose is synthesised from triacylglycerol via core metabolic processes. Mutants with defects in triacylglycerol-to-sucrose conversion display
Hiromitsu Tabeta   +8 more
doaj   +1 more source

Activation of tyrosine kinases by mutation of the gatekeeper threonine. [PDF]

open access: yes, 2008
Protein kinases targeted by small-molecule inhibitors develop resistance through mutation of the gatekeeper threonine residue of the active site. Here we show that the gatekeeper mutation in the cellular forms of c-ABL, c-SRC, platelet-derived growth ...
Azam, Mohammad   +4 more
core   +1 more source

Threonine Facilitates Cd Excretion by Increasing the Abundance of Gut Escherichia coli in Cd-Exposed Mice

open access: yesMolecules, 2022
Cadmium (Cd) can easily enter the body through the food chain and threaten health since Cd pollution is prevalent in the environment. Gut microbiota is necessary for the reduction of metal ions. To reduce Cd-induced harmful impacts and Cd accumulation in
Yongbin Li   +9 more
doaj   +1 more source

Hanks-Type Serine/Threonine Protein Kinases and Phosphatases in Bacteria: Roles in Signaling and Adaptation to Various Environments [PDF]

open access: yes, 2018
Reversible phosphorylation is a key mechanism that regulates many cellular processes in prokaryotes and eukaryotes. In prokaryotes, signal transduction includes two-component signaling systems, which involve a membrane sensor histidine kinase and a ...
Janczarek, Monika   +3 more
core   +1 more source

Role of threonine dehydrogenase in Escherichia coli threonine degradation [PDF]

open access: yesJournal of Bacteriology, 1977
Threonine was used as nitrogen source by Escherichia coli K-12 through a pathway beginning with the enzyme threonine dehydrogenase. The 2-amino-3-ketobutyrate formed was converted to glycine, and the glycine was converted to serine, which acted as the actual nitrogen donor.
R, Potter, V, Kapoor, E B, Newman
openaire   +2 more sources

THE MUTANT STRAINS OF MICROORGANISMS ‒ PRODUCERS OF LYSINE AND THREONINE [PDF]

open access: yesBiotechnologia Acta, 2014
Strains-producers of essential amino acids of aspartate family such as Corynebacterium glutamicum, Brevibacterium flavum, Brevibacterium sp. 90, Brevibacterium sp. 90H, Brevibacterium sp.
G. S. Andriiash   +2 more
doaj   +1 more source

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