Journal of Biological Chemistry, 1995 Protein kinases activated by dual phosphorylation on Tyr and Thr (MAP kinases) can be grouped into two major classes: ERK and JNK. The ERK group regulates multiple targets in response to growth factors via a Ras-dependent mechanism.
J. Raingeaud +6 more
semanticscholar +1 more source
The Serine/Threonine Protein Kinase (Akt)/ Protein Kinase B (PkB) Signaling Pathway in Breast Cancer [PDF]
, 2020 According to statistical data published in 2019, breast cancer is among the leading causes of death in women worldwide. The serine/threonine kinase (AKT) or protein kinase B (PkB) signaling pathway is activated by phosphorylation processes, which further
Bratu, Ovidiu Gabriel +8 more
core +3 more sources
Orbital: The Electronic Journal of Chemistry, 2018 Venoms of social wasps have in their composition proteins, peptides, among others and several of these compounds were evaluated for their function in the venom, however, there is still no study of the quantification of free amino acids of venom of social
Viviana de Oliveira Torres +3 more
doaj +1 more source
Effect of Threonine Supplementation on Growth Performance, Metabolizable Energy, Morphological Changes and Immune Response in Broiler Chickens Challenged with Coccidia [PDF]
Poultry Science Journal, 2020 This study was performed to investigate the effects of dietary threonine (Thr). level on performance, metabolizable energy, intestinal morphology, and immune system in coccidian–infected broiler chickens.
Mehdipour Z +3 more
doaj +1 more source
Glycine, serine and threonine metabolism confounds efficacy of complement-mediated killing
Nature Communications, 2019 Serum resistance is a poorly understood but common trait of some difficult-to-treat pathogenic strains of bacteria. Here, we report that glycine, serine and threonine catabolic pathway is down-regulated in serum-resistant Escherichia coli, whereas ...
Zhi-xue Cheng +11 more
semanticscholar +1 more source
Biochemistry, 2014 OGlcNAcylation and phosphorylation are the major competing intracellular post-translational modifications of serine and threonine residues. The structural effects of both post-translational modifications on serine and threonine were examined within ...
Michael Elbaum, Neal J. Zondlo
openalex +2 more sources
Differentiation Between Ripening Stages of Iberian Dry-Cured Ham According to the Free Amino Acids Content [PDF]
, 2020 In this paper, the differentiation of three ripening stages, postsalting, drying, and cellar, of Iberian dry-cured ham has been carried out according to their free amino acids contents. Eighteen L-amino acids, alanine, 2-aminobutanoic acid, aspartic acid,
Alcázar Rueda, Ángela +3 more
core +1 more source
On the Microbiological Assay of Threonine [PDF]
Journal of General Microbiology, 1952 SUMMARY: A small lag section has been noticed in the standard curves obtained in the estimation of threonine using Streptococcus faecalis R. An increase in the acetate and phosphate buffers in the basal medium has been found to be advantageous.
S C, BALASUBRAMANIAN, M, RAMACHANDRAN
openaire +2 more sources
LRRK2 phosphorylates pre-synaptic N-ethylmaleimide sensitive fusion (NSF) protein enhancing its ATPase activity and SNARE complex disassembling rate [PDF]
, 2016 Background Lrrk2, a gene linked to Parkinson\u2019s disease, encodes a large scaffolding protein with kinase and GTPase activities implicated in vesicle and cytoskeletal-related processes.
Arrigoni, Giorgio +15 more
core +5 more sources
A Novel Peptide-Based SILAC Method to Identify the Posttranslational Modifications Provides Evidence for Unconventional Ubiquitination in the ER-Associated Degradation Pathway. [PDF]
, 2013 The endoplasmic reticulum-associated degradation (ERAD) pathway is responsible for disposing misfolded proteins from the endoplasmic reticulum by inducing their ubiquitination and degradation.
Anania, Veronica +4 more
core +3 more sources