Results 41 to 50 of about 514,103 (332)

Threonine utilization is high in the intestine of piglets [PDF]

, 2005
The whole-body threonine requirement in parenterally fed piglets is substantially lower than that in enterally fed piglets, indicating that enteral nutrition induces intestinal processes in demand of threonine.
Baker, Ballevre, Barbara Stoll, Battezzati, Bertolo, Bikker, Biolo, Bouteloup-Demange, Burrin, Chu, Dekker, Douglas G. Burrin, Dudley, Dudley, Ebner, Fuller, Hegsted, Henk Schierbeek, Hoerr, Hoerr, Huşek, Johannes B. van Goudoever, Lobley, Maaike W. Schaart, Matthews, McNurlan, Peter J. Reeds, Reeds, Roberton, Seve, Sophie R. D. van der Schoor, Stoll, Stoll, Stoll, Stoll, van der Schoor, Van Der Schoor, van Goudoever, Van Klinken, Waterlow, Wu, Yu, Yu   +42 more
core   +2 more sources

Estrogen Protects the Female Heart from Ischemia/Reperfusion Injury through Manganese Superoxide Dismutase Phosphorylation by Mitochondrial p38β at Threonine 79 and Serine 106. [PDF]

, 2016
A collective body of evidence indicates that estrogen protects the heart from myocardial ischemia/reperfusion (I/R) injury, but the underlying mechanism remains incompletely understood. We have previously delineated a novel mechanism of how 17β-estradiol
Kim, Jin Kyung, Liu, Han, Luo, Tao
core   +1 more source

Gamma-D crystallin gene (CRYGD) mutation causes autosomal dominant congenital cerulean cataracts [PDF]

, 2003
Congenital cataracts are a major cause of bilateral visual impairment in childhood. We mapped the gene responsible for autosomal congenital cerulean cataracts to chromosome 2q33-35 in a four generation family of Moroccan descent. The maximum lod score (7.
Abitbol, M., Arbogast, L., Basak, Ajit K., Benazzouz, B., Berraho, A., Boutayeb, S., Cherif Chefchaouni, M., Gribouval, O., Hajaji, Y., Hilal, L., Nandrot, E., Slingsby, Christine   +11 more
core   +2 more sources

Effects of different dietary threonine and glycine supplies in broilers fed low-protein diets

Frontiers in Veterinary Science
The reduction of crude protein (CP) content of broiler diets with balanced amino acid supply can increase the nitrogen (N) utilization efficiency and reduce ammonia emission, the risk of many health problems in birds.
Patrik Strifler, Boglárka Horváth, Nikoletta Such, Károly Dublecz, László Pál   +4 more
doaj   +1 more source

Free radical destruction of hydroxyl-containing amino acids

Журнал Белорусского государственного университета: Химия, 2019
А new way of the free radical ROS- and HOCl-induced destruction of serine, threonine, and their peptide derivatives due to the nitrogen-centered radicals formation and their subsequent decomposition with the side chain elimination has been established ...
Anastasia A. Sladkova, Irina P. Edimecheva, Anna A. Sosnovskaya, Oleg I. Shadyro   +3 more
doaj   +1 more source

Mutations of the BRAF gene in human cancer [PDF]

, 2002
Cancers arise owing to the accumulation of mutations in critical genes that alter normal programmes of cell proliferation, differentiation and death. As the first stage of a systematic genome-wide screen for these genes, we have prioritized for analysis ...
Bignell, G.R., Bigner, D.D., Bottomley, W., Chenevix-Trench, G., Clegg, S., Cooper, C., Cossu, A., Cox, C., Darrow, T.L., Davies, H., Davis, N., Dicks, E., Edkins, S., Ewing, R., Flanagan, A., Floyd, Y., Futreal, P.A., Garnett, M.J., Gray, K., Gusterson, B.A., Hall, S., Hargrave, D., Hawes, R., Ho, J.W.C., Hooper, S., Hughes, J., Jayatilake, H., Kosmidou, V., Leung, S.Y., Maitland, N., Marais, R., Marshall, C.J., Menzies, A., Mould, C., Nicholson, A., Palmieri, G., Parker, A., Paterson, H., Pritchard-Jones, K., Riggins, G.J., Seigler, H.F., Shipley, J., Stephens, P., Stevens, C., Stratton, M.R., Teague, J., Watt, S., Weber, B.L., Wilson, R., Woffendin, H., Wooster, R., Yuen, S.T.   +51 more
core   +1 more source

Differentiation Between Ripening Stages of Iberian Dry-Cured Ham According to the Free Amino Acids Content [PDF]

, 2020
In this paper, the differentiation of three ripening stages, postsalting, drying, and cellar, of Iberian dry-cured ham has been carried out according to their free amino acids contents. Eighteen L-amino acids, alanine, 2-aminobutanoic acid, aspartic acid,
Alcázar Rueda, Ángela, Jurado Jurado, José Marcos, León Camacho, Manuel, Pablos Pons, Fernando de   +3 more
core   +1 more source

Modifications in FLAP's second cytosolic loop influence 5‐LOX interaction, inhibitor binding, and leukotriene formation

FEBS Letters, EarlyView.
The enzyme 5‐lipoxygenase (5‐LOX) catalyzes the first step in the biosynthesis of leukotrienes (LTs) involved in inflammatory pathophysiology. After cellular stimulation, 5‐LOX translocates to the nucleus, interacting with the 5‐LOX‐activating protein (FLAP) to form LTA4 from arachidonic acid (AA).
Erik Romp, Katharina Rataj, Stefanie König, Marcia E. Newcomer, Oliver Werz, Ulrike Garscha   +5 more
wiley   +1 more source

Threonine Phosphorylation and the Yin and Yang of STAT1: Phosphorylation-Dependent Spectrum of STAT1 Functionality in Inflammatory Contexts

Cells
Threonine phosphorylation promotes inflammatory functions of STAT1 while restricting its interferon (IFN) signaling in innate immune responses. However, it remains unclear whether the restriction of STAT1-mediated IFN signaling conferred by threonine ...
Maha M. Elbrashy, Hozaifa Metwally, Shuhei Sakakibara, Tadamitsu Kishimoto   +3 more
doaj   +1 more source

The carboxylate “gripper” of the substrate is critical for C‐4 stereo‐inversion by UDP‐glucuronic acid 4‐epimerase

FEBS Letters, EarlyView.
UDP‐glucuronic acid 4‐epimerase (UGAepi) catalyzes NAD+‐dependent interconversion of UDP‐glucuronic acid (UDP‐GlcA) and UDP‐galacturonic acid (UDP‐GalA) via C4‐oxidation, 4‐keto‐intermediate rotation, and C4‐reduction. Here, Borg et al. examined the role of the substrate's carboxylate group in the enzymic mechanism by analyzing NADH‐dependent reduction
Annika J. E. Borg, Laura De Cnop, Bernd Nidetzky   +2 more
wiley   +1 more source