Results 111 to 120 of about 2,631,672 (317)
Jurnal Riset Kesehatan, 2017 Aorta abdomen CTA adalah pemeriksaan radiologis minimal invasif dengan media kontras yang masuk melalui pembuluh darah, yang bertujuan menghasilkan radiografi aorta abdomen dengan menggunakan modalitas CT-Scan.
Nisa Izzaty Khoirina +2 more
doaj +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Searching Threshold Inflation for India [PDF]
The present study is an effort to examine econometrically the presence of threshold level of inflation for India, in an environment where expected inflation is in double digit.
Prakash Singh
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Protein sequestration generates a flexible ultrasensitive response in a genetic network
Molecular Systems Biology, 2009 Ultrasensitive responses are crucial for cellular regulation. Protein sequestration, where an active protein is bound in an inactive complex by an inhibitor, can potentially generate ultrasensitivity. Here, in a synthetic genetic circuit in budding yeast,
Nicolas E Buchler, Frederick R Cross
doaj +1 more source
Transport, 2003 In this article the statical and cyclical strength investigations of austempered ductile cast iron (ADI) are presented. ADI material becomes more and more popular. Ductile iron is lighter than steel and its mechanical properties are better.
Mindaugas LeonaviÄius +3 more
doaj +1 more source
The Utility of Thresholds and the Threshold Utility [PDF]
Medical Decision Making, 1987 S G, Pauker, S P, Pauker, J B, Wong
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Subsampling inference in threshold autoregressive models [PDF]
This paper discusses inference in self exciting threshold autoregressive (SETAR) models. Of main interest is inference for the threshold parameter. It is well-known that the asymptotics of the corresponding estimator depend upon whether the SETAR model ...
Michael Wolf, Jesús Gonzalo
core