Results 111 to 120 of about 5,396,056 (299)
Continuous Wavelet Transform and Hidden Markov Model Based Target Detection [PDF]
Standard tracking filters perform target detection process by comparing the sensor output signal with a predefined threshold. However, selecting the detection threshold is of great importance and a wrongly selected threshold causes two major problems ...
Efe, M., Tuğaç, S.
core +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Stochastic and Temporal Models of Olfactory Perception
Olfactory systems typically process signals produced by mixtures composed of very many natural odors, some that can be elicited by single compounds. The several hundred different olfactory receptors aided by several dozen different taste receptors are ...
Thomas P. Hettinger, Marion E. Frank
doaj +1 more source
THE NEURASTHENIC AT THE THRESHOLD [PDF]
It is still quite the custom in professional as well as in lay circles to tag the proverbial neurasthenic a physiologic enigma, or a psychologic joke, or some kind of an ill-defined cross between the two. In view of the various and often fanciful versions of his disorder, there is ample room for some public ridicule.
openaire +1 more source
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
The notion of Threshold: an investigation into conceptual accompaniment in Aristotle and Hegel
What is unique to the idea of a threshold is that it is a threshold’s proper definition to generate or signal an inevitable accompanying image of a surrounding boundary or a further field of exploration, even though these accompanying terms or images ...
Jason Carter
doaj
Opportunity Knocks: An Economic Analysis of Television Advertisements [PDF]
Certain aspects of advertising–especially on television–are not easily explained with conventional economic models. In particular, much of the imagery and repetitive thematic content seen in advertisements suggests it is "psychological" in nature, as ...
Hanks, Andrew +2 more
core
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source

