Results 31 to 40 of about 2,631,672 (317)

Threshold signatures from VOLE

, 2023
reservedThe focus of this thesis is on threshold digital signatures and in particular on Schnorr signatures (1991). Following the expiration of its patent in 2008, Schnorr signature has gained significance in the realm of digital signatures due to its ...
MARCHIORO, ALESSANDRO
core  

T160‐phosphorylated CDK2 defines threshold for HGF‐dependent proliferation in primary hepatocytes

Molecular Systems Biology, 2015
Liver regeneration is a tightly controlled process mainly achieved by proliferation of usually quiescent hepatocytes. The specific molecular mechanisms ensuring cell division only in response to proliferative signals such as hepatocyte growth factor (HGF)
Stephanie Mueller, Jérémy Huard, Katharina Waldow, Xiaoyun Huang, Lorenza A D'Alessandro, Sebastian Bohl, Kathleen Börner, Dirk Grimm, Steffen Klamt, Ursula Klingmüller, Marcel Schilling   +10 more
doaj   +1 more source

Forecasting the Dialysis Burden in Japan: Validation‐Based Projections of Prevalence and Incidence Through 2050

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Japan has one of the highest dialysis prevalence rates worldwide and a shrinking, aging population. Whether dialysis burden has entered a sustained post‐peak phase or whether recent declines partly reflect pandemic‐related disruptions remains uncertain.
Hatice Şahin, Berrak Itır Aylı, Nüket Paksoy   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Thresholds and mechanisms of human magnetophosphene perception induced by low frequency sinusoidal magnetic fields

Brain Stimulation
Background: Virtually everyone is exposed to power-frequency MF (50/60 Hz), inducing in our body electric fields and currents, potentially modulating brain function.
Alexandre Legros, Janita Nissi, Ilkka Laakso, Joan Duprez, Robert Kavet, Julien Modolo   +5 more
doaj   +1 more source

The shape of the contact–density function matters when modelling parasite transmission in fluctuating populations [PDF]

Royal Society Open Science, 2017
Models of disease transmission in a population with changing densities must assume a relation between infectious contacts and density. Typically, a choice is made between a constant (frequency-dependence) and a linear (density-dependence) contact–density
Benny Borremans, Jonas Reijniers, Niel Hens, Herwig Leirs   +3 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Human achromatic flickers and phosphenes thresholds under extremely low frequency electric stimulations

Scientific Reports
Human exposure to extremely low-frequency (
Nicolas Bouisset, Andres Carvallo, Maorie Laporte, Alexandre Legros   +3 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Frequency responses of human magnetophosphene perception thresholds during dark adaptation point to rod modulation

Experimental Physiology
Magnetophosphenes are flickering lights perceived when an extremely low frequency magnetic field generates a sufficiently strong electric field in the head.
Nicolas Bouisset, Andres Carvallo, Sebastien Villard, Ilkka Laakso, Alexandre Legros   +4 more
doaj   +1 more source