Results 101 to 110 of about 3,798,889 (297)
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
Quantum nonlocality of Heisenberg XX model with Site-dependent Coupling Strength
, 2003 We show that the generalized Bell inequality is violated in the extended Heisenberg model when the temperature is below a threshold value. The threshold temperature values are obtained by constructing exact solutions of the model using the temperature ...
Bell J S +9 more
core +1 more source
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Genetic parameters for pathogen-specific mastitis resistance in Danish Holstein Cattle
Animal, 2009 The objective of this study was to estimate heritabilities for and genetic correlations among different pathogen-specific mastitis traits. The traits were unspecific mastitis, which is all mastitis treatments regardless of the causative pathogen as well ...
L.P. Sørensen +3 more
doaj +1 more source
Coexistence in Threshold Voter Models
The Annals of Probability, 1994 zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire +2 more sources
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
EconomiesThis study investigates the nonlinear effects of air pollution on urban entertainment consumption by analyzing daily PM10 levels and movie box office data across 334 Chinese cities from 2012 to 2022, resulting in a total of 1,250,339 observations ...
Wei Ma, Zhaolei Liu, Yuning Gao
doaj +1 more source
Arquivo Brasileiro de Medicina Veterinária e Zootecnia, 1999 Registros de sobrevivência do nascimento ao desmame de 3846 crias de ovinos da raça Santa Inês foram analisados por modelos de reprodutor linear e não linear (modelo de limiar), para estimar componentes de variância e herdabilidade.
W.H. Sousa, C.S. Pereira, F.L.R. Silva
doaj +1 more source
Threshold Effects in Cigarette Addiction: An Application of the Threshold Model in Dynamic Panels [PDF]
We adopt the threshold model of myopic cigarette addiction to US state-level panel data. The threshold model is used to identify the structural effects of cigarette demand determinants across the income stratification.
Chang-Ching Lin, Yi-Chi Chen
core
Continuous Wavelet Transform and Hidden Markov Model Based Target Detection [PDF]
, 2014 Standard tracking filters perform target detection process by comparing the sensor output signal with a predefined threshold. However, selecting the detection threshold is of great importance and a wrongly selected threshold causes two major problems ...
Efe, M., Tuğaç, S.
core +1 more source