Results 81 to 90 of about 16,597,684 (304)
Threshold Effects in Cigarette Addiction: An Application of the Threshold Model in Dynamic Panels [PDF]
We adopt the threshold model of myopic cigarette addiction to US state-level panel data. The threshold model is used to identify the structural effects of cigarette demand determinants across the income stratification.
Yi-Chi Chen, Chang-Ching Lin
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
tail behavior of a threshold autoregressive stochastic volatility model [PDF]
We consider a threshold autoregressive stochastic volatility model where the driving noises are sequences of iid regurlarly random vatiables. We prove that both the right and the left tails of the marginal distribution of the log-volatility process are ...
Dominique Guegan, Aliou Diop
core
Covariate-varying threshold selection method in non-stationary generalized pareto model [PDF]
, 2019 Non-stationary data usually exist in real life and influenced by covariates. The non-stationary extremes are usually modelled by setting a constant high threshold, u, where the threshold exceedances are modelled by Generalized Pareto distribution (GP ...
Ali, Norhaslinda +2 more
core +1 more source
Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis
FEBS Letters, EarlyView.This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng +8 more
wiley +1 more source
FEBS Letters, EarlyView.Vacuolar H+‐ATPase (V‐ATPase) is a multisubunit rotary proton pump that acidifies intracellular compartments. Using elastic network models, we identified conserved hinge residues that govern its large‐scale functional motions. We show that intrinsically encoded ‘soft modes’ drive critical functional transitions, including rotary catalysis and ...
Diksha Parwana +3 more
wiley +1 more source
"Threshold Effects in the U.S. Budget Deficit" [PDF]
We contribute to the debate on whether the large U.S. federal budget deficits are sustainable in the long run. We model the U.S. government deficit per capita as a threshold autoregressive process. We find evidence that the U.S.
Andrea Cipollini +2 more
core
Threshold concept knowledge in analogue electronics: Support and assessment [PDF]
, 2012 In electrical engineering, as in other academic disciplines, there exist special, threshold concepts, where students often get stuck but which once grasped reveal new ways of thinking about a subject.
Scott, Jonathan B. +2 more
core
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
AnimalsChronic progressive lymphedema (CPL) is a prevalent and progressive disease in Rhenish German draught horses. The objective of our follow-up study was to evaluate the heritability of this disease in Rhenish German draught horses using pedigree-based and ...
Johanna Sievers, Ottmar Distl
doaj +1 more source