Results 61 to 70 of about 1,475,278 (264)
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cogent Business & ManagementEntrepreneurial efficiency (EE) promotion is an important component of urban governance, but how high-quality economic development can affect EE has not been deeply discussed. Based on the cross-sectional data of business incubators in 287 Chinese cities,
Jinlin Cheng +4 more
doaj +1 more source
Czech Journal of Animal Science, 2004 The paper presents an algorithm for the estimation and prediction of parameters in a two-trait binary threshold model. The model includes fixed effects and the following random effects: genetic direct additive, genetic maternal additive and permanent ...
E. Skotarczak +4 more
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Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Agricultural Economics (AGRICECON)Agricultural carbon emissions (ACE) is a critical contributor to global greenhouse gas emissions, which have already become a common challenge for global carbon reduction.
Yumiao Zhang, Qi Yin, Yufan Wu, Kun Ma
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Genetic parameters for dystocia, milk yield and age at first calving in Brazilian Holstein cows
Journal of Applied Animal Research, 2021 The present study aims to estimate genetic parameters for dystocia, milk yield and age at first calving of Holstein cows reared in intensive production systems located in the southeastern region of Brazil.
Gabriela Stefani +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
LandUnder the robust impetus of China’s rural revitalization strategy, agro-tourism integration and tourism-driven poverty reduction have profoundly impacted various aspects of China’s economy, society, and ecology. This has propelled coordinated urban–rural
Debin Ma, Dongqi Sun, Ziyi Wang
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Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source