Results 101 to 110 of about 16,597,684 (304)

The Role of Air Pollution in Shaping Urban Cultural Consumption: An Empirical Investigation of PM10 and Movie Consumption in Chinese Cities

open access: yesEconomies
This study investigates the nonlinear effects of air pollution on urban entertainment consumption by analyzing daily PM10 levels and movie box office data across 334 Chinese cities from 2012 to 2022, resulting in a total of 1,250,339 observations ...
Wei Ma, Zhaolei Liu, Yuning Gao
doaj   +1 more source

Structural Biology of the FGF7 Subfamily

open access: yesFrontiers in Genetics, 2019
Mammalian fibroblast growth factor (FGF) signaling is intricately regulated via selective binding interactions between 18 FGF ligands and four FGF receptors (FGFR1–4), three of which (FGFR1–3) are expressed as either epithelial (“b”) or mesenchymal (“c”)
Allen Zinkle, Moosa Mohammadi
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

A Hybrid Mechanism for Innovation Diffusion in Social Networks

open access: yesIEEE Access, 2016
Innovation diffusion is the process of adopting novel things, which is deemed as the diffusion of human behaviors. Previous studies mainly posit an unclear distinction with information diffusion.
Jun Zhang   +6 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Cumulative t-link threshold models for the genetic analysis of calving ease scores

open access: yesGenetics Selection Evolution, 2003
In this study, a hierarchical threshold mixed model based on a cumulative t-link specification for the analysis of ordinal data or more, specifically, calving ease scores, was developed. The validation of this model and the Markov chain Monte Carlo (MCMC)
Tempelman Robert J   +4 more
doaj   +1 more source

A Threshold Model of Financial Markets

open access: yesActa Physica Polonica A, 2008
We proposed a model of interacting market agents based on the Ising spin model. The agents can take three actions: "buy," "sell," or "stay inactive." We defined a price evolution in terms of the system magnetization. The model reproduces main stylized facts of real markets such as: fat-tailed distribution of returns and volatility clustering.
Sieczka, Paweł, Hołyst, Janusz A.
openaire   +2 more sources

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Coexistence in Threshold Voter Models

open access: yesThe Annals of Probability, 1994
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
openaire   +2 more sources

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