ABSTRACT Objective Building on our prior Behavioral Risk Factor Surveillance System analysis identifying adults aged 18–39 as the primary driver of the national increase in self‐reported cognitive disability, we examined factors associated with this rise using 2013–2024 U.S. BRFSS data. Methods We analyzed U.S.
Adam de Havenon +9 more
wiley +1 more source
Characterizing Cutaneous α‐Synuclein Deposition and Seeding Activity in Parkinson's Disease Subtypes
ABSTRACT Objective Cutaneous phosphorylated α‐synuclein (p‐syn) and α‐synuclein seeding activity are promising biomarkers for Parkinson's disease (PD), but their clinical value remains uncertain due to disease heterogeneity. This study evaluates these two biomarkers in PD patients to inform phenotype‐specific diagnosis and disease severity assessment ...
Yuting Jin +8 more
wiley +1 more source
ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
ABSTRACT Objective To investigate which baseline clinical and imaging characteristics best predict TSPO‐PET‐measurable reduction in glial activation following treatment of multiple sclerosis (MS), to utilize this information for designing more efficient biomarker‐based clinical trials targeting glial activation.
Marlene T. Morch +5 more
wiley +1 more source
Deep Learning Pose Estimation for Phenotyping of Co‐Occurring Hyperkinetic Movement Disorders
ABSTRACT Objective To explore whether routine outpatient video combined with deep learning‐based pose estimation and clinically interpretable kinematic features can support multi‐label phenotyping of co‐occurring hyperkinetic movement disorders (HMDs).
Laura Cif +17 more
wiley +1 more source
Combined Nav1.7-Nav1.8 channel abrogation: Supralinear suppression of excitability in a subpopulation of peripheral sensory neurons. [PDF]
Vasylyev D +4 more
europepmc +1 more source
From footsteps to wireless events: infrastructure-native battery-free interfaces for human-environment interactions. [PDF]
Zheng Y +8 more
europepmc +1 more source
Quantifying the Transmit-Power Threshold for Reliable Passive Detuning of Inductively Coupled Wireless Resonators in MRI: A Phantom Study. [PDF]
Lu M +7 more
europepmc +1 more source
A VHF-Voltage Double Time Integral Method for Apparent-Charge Estimation of Partial Discharge in Gas-Insulated Switchgear. [PDF]
Gao S, Zhou X, Pan C, Qian Y, Sheng G.
europepmc +1 more source
Adaptive Arc-Voltage Control for Narrow-Gap Pulsed TIG Welding Based on Feedback Reconstruction and Effective-Error Identification. [PDF]
Fan H +5 more
europepmc +1 more source

