Results 131 to 140 of about 137,983 (312)

Weighted Opposition-Based Fuzzy Thresholding [PDF]

open access: yes, 2011
With the rapid growth of the digital imaging, image processing techniques are widely involved in many industrial and medical applications. Image thresholding plays an essential role in image processing and computer vision applications.
Ensafi, Pegah
core  

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Segmentation of bone structures in Magnetic Resonance Images (MRI) for human hand skeletal kinematics modelling [PDF]

open access: yes, 2011
Roboticists have shown a great interest in designing and building robotic hands, mainly because of the complex structure and high range of functionalities that the human hand has.
Rusu, Alexandru
core  

CEACAM1 participation in breast cancer progression

open access: yesMolecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin   +3 more
wiley   +1 more source

Multilevel thresholding based on mean shift mode seeking

open access: yes, 2011
A novel multilevel thresholding method based on mean shift procedure is proposed to resolve the problem that the optimal number of thresholds for multilevel thresholding can usually not be predetermined.
Ma Junyong   +4 more
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Blind white denoising of speech signals

open access: yesVisión Electrónica, 2012
Discrete Wavelet Transform (DWT) has been used in the recent years in signal processing applications, i.e. filtering and compression. In the case of denoising because the energy of the noise is spread in the entire wavelet coefficients and it has low ...
Luis F. Pedraza   +2 more
doaj  

Adaptive Wavelet Estimation: A Block Thresholding And Oracle Inequality Approach

open access: yes, 1998
We study wavelet function estimation via the approach of block thresholding and ideal adaptation with oracle. Oracle inequalities are derived to offer insights into the balance and tradeoff between block size and threshold level.
Estimator Adaptivity   +4 more
core  

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

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