Results 141 to 150 of about 137,983 (312)
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Integral image based fast algorithm for two-dimensional Otsu thresholding
, 2008 As the classic image segmentation technique, Otsu adaptive thresholding method is widely employed in image processing and computer vision. Two-dimensional Otsu thresholding algorithm was regarded as an effective improvement of the original Otsu method ...
Hao YM(郝颖明) +3 more
core
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
SensorsGround-penetrating radar (GPR) has been proven effective for detecting subsurface pipes in a nondestructive way, typically with manual processing and decision-making.
Zhengyi Shi +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Loss of eIF5A rewires thapsigargin‐mediated endoplasmic reticulum stress responses in multiple myeloma cells by selective translation of mRNA transcripts, consequently dampening thapsigargin‐induced unfolded protein response (UPR) activation and shifting the balance from induction of apoptosis toward cell survival and proliferation.
Demi Both +7 more
wiley +1 more source
Road Crack Detection and Orientation Estimation Using Airborne Synthetic Aperture Radar
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingCracks on road surfaces are a significant safety hazard that can progress into larger potholes, posing risks to vehicles and passengers. Synthetic aperture radar (SAR) data acquired by high-resolution airborne SAR systems are sensitive to changes on the ...
Arun Babu +2 more
doaj +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico +5 more
wiley +1 more source
AgricultureThe advent of smart farms, enabled by information and communication technologies (ICT) and the Internet of Things (IoT), has improved productivity and sustainable agriculture.
Chi-Yong An, Jinki Park, Chulmin Song
doaj +1 more source
Fast automatic multilevel thresholding method
, 2002 Previous optimal thresholding methods are popular and efficient in the case of bi-level thresholding but are computationally expensive when extended to multilevel thresholding to optimise the objective functions.
Shi, ZK +5 more
core +1 more source