Results 141 to 150 of about 123,159 (318)
Molecular Oncology, EarlyView.Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
Road Crack Detection and Orientation Estimation Using Airborne Synthetic Aperture Radar
IEEE Journal of Selected Topics in Applied Earth Observations and Remote SensingCracks on road surfaces are a significant safety hazard that can progress into larger potholes, posing risks to vehicles and passengers. Synthetic aperture radar (SAR) data acquired by high-resolution airborne SAR systems are sensitive to changes on the ...
Arun Babu +2 more
doaj +1 more source
Enhanced monopulse radar tracking using empirical mode decomposition
, 2010 Monopulse radar processors are used to track targets that appear in the look direction beamwidth. The target tracking information (range, azimuth angle, and elevation angle) are affected when manmade high power interference (jamming) is introduced to the
Elgamel, Sherif A.E.H., Soraghan, J.J.
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Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
EbayesThresh: R Programs for Empirical Bayes Thresholding
Suppose that a sequence of unknown parameters is observed sub ject to independent Gaussian noise. The EbayesThresh package in the S language implements a class of Empirical Bayes thresholding methods that can take advantage of possible sparsity in the ...
Iain Johnstone, Bernard W. Silverman
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, 2011 Roboticists have shown a great interest in designing and building robotic hands, mainly because of the complex structure and high range of functionalities that the human hand has.
Rusu, Alexandru
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Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Streaming Robust Submodular Maximization: A Partitioned Thresholding Approach [PDF]
We study the classical problem of maximizing a monotone submodular function subject to a cardinality constraint k, with two additional twists: (i) elements arrive in a streaming fashion and (ii) m items from the algorithm’s memory might be removed after ...
Mitrovic, Slobodan +4 more
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