Results 121 to 130 of about 137,983 (312)
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source
The Utility of Thresholds and the Threshold Utility [PDF]
Medical Decision Making, 1987 S G, Pauker, S P, Pauker, J B, Wong
openaire +2 more sources
, 2014 (CGIHT) for compressed sensing combines the low per iteration computational cost of simple line search iterative hard thresholding algorithms with the improved convergence rates of more sophisticated sparse approximation algorithms.
Iterative Hard Thresholding +3 more
core
Molecular Oncology, EarlyView.Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
EbayesThresh: R Programs for Empirical Bayes Thresholding [PDF]
Suppose that a sequence of unknown parameters is observed sub ject to independent Gaussian noise. The EbayesThresh package in the S language implements a class of Empirical Bayes thresholding methods that can take advantage of possible sparsity in the ...
Iain Johnstone, Bernard W. Silverman
core
Unsupervised thresholding of video images
, 2004 Thresholding of video images is a great challenge because of their low spatial resolution and complex background. We investigate the issue of thresholding these images by reducing the number of colors to improve automated text detection and recognition ...
Chang, Chein-I +2 more
core +1 more source
Space-Varying Coefficient Models for Diffusion Tensor Imaging using 3d Wavelets [PDF]
, 2006 In this paper, the space-varying coefficients model on the basis of B-splines (Heim et al., (2006)) is adapted to wavelet basis functions and re-examined using artificial and real data. For an introduction to diffusion tensor imaging refer to Heim et al.
Heim, Susanne
core +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Folklore: Electronic Journal of Folklore, 2015 This study explores accounts of the revenant, the walking dead in medieval Britain through the concept of a failure in the ritual process that surrounded death. This concept is used to explore the rituals leading to, surrounding, and following death, as well as the consequences of their perceived failure.
openaire +3 more sources
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source