Results 121 to 130 of about 123,159 (318)

A New Soft-Thresholding Image Denoising Method

open access: yes, 2012
In this paper, we propose a new method of noise removal from an image corrupted with Gaussian noise using soft-thresholding. There are two types of thresholding: Soft and Hard thresholding. The Universal thresholding method i.e.
Biswas, Mantosh, Om, Hari
core   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

open access: yesMolecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel   +12 more
wiley   +1 more source

CVTresh: R Package for Level-Dependent Cross-Validation Thresholding

open access: yes
The core of the wavelet approach to nonparametric regression is thresholding of wavelet coefficients. This paper reviews a cross-validation method for the selection of the thresholding value in wavelet shrinkage of Oh, Kim, and Lee (2006), and introduces
Hee-Seok Oh, Donghoh Kim
core  

An improvement in the moment-preserving thresholding method

open access: yes, 2010
[[abstract]]Thresholding is frequently used for image segmentation. One of the most popular approach to thresholding is the moment-preserving thresholding method proposed by Tsai in 1985.
Chen, I.-Ping ; Lai, Ming-Yi ; Wang, Ling-Ling
core  

Weighted Opposition-Based Fuzzy Thresholding [PDF]

open access: yes, 2011
With the rapid growth of the digital imaging, image processing techniques are widely involved in many industrial and medical applications. Image thresholding plays an essential role in image processing and computer vision applications.
Ensafi, Pegah
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

Adaptive Wavelet Estimation: A Block Thresholding And Oracle Inequality Approach

open access: yes, 1998
We study wavelet function estimation via the approach of block thresholding and ideal adaptation with oracle. Oracle inequalities are derived to offer insights into the balance and tradeoff between block size and threshold level.
Estimator Adaptivity   +4 more
core  

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

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