Results 71 to 80 of about 68,330 (260)
Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]
, 2016 Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core +2 more sources
Thrombectomy for Acute Internal Carotid Thrombosis: Five Thrombectomy Devices Compared [PDF]
European Journal of Vascular and Endovascular Surgery, 2004 To test the safety and efficiency of commercially available thrombectomy catheters in clearing simulated internal carotid artery (ICA) thrombosis.Comparative in vitro study.A model of the ICA was filled with human thrombus, the 'circle of Willis' back pressure was set at either 10 or 30 cm of water.
Chant, Harvey +2 more
openaire +3 more sources
Cytoprotection Concepts for Ischemic Stroke in the Recanalization Era
Advanced Science, EarlyView.This review provides detailed information on modern cytoprotective strategies for ischemic stroke in the context of recanalization therapies. It derives their rationale based on contemporary knowledge of stroke pathophysiology and discusses the role of advanced imaging approaches as well as concepts for novel clinical trial designs.
Johannes Boltze, Marc Fisher
wiley +1 more source
Animal Models and Experimental Medicine, EarlyView.Diabetes combined with ischemic stroke (DMIS) exacerbates brain infarct size and neuronal damage compared to nondiabetic ischemic stroke (IS). This study reveals that microRNA‐34a (miR‐34a) plays a key role in DMIS pathogenesis: miR‐34a directly targets and suppresses brain‐derived neurotrophic factor (BDNF) and Sine oculis homeobox 3 (SIX3), promoting
Ling Zhao +5 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective Immunothrombosis contributes to ischemic stroke pathophysiology through neutrophil extracellular trap (NET) formation, which promotes thrombus stabilization and microvascular dysfunction. DNase1 is the principal endonuclease responsible for NET degradation.
B. Díaz‐Benito +10 more
wiley +1 more source
Assessment of Vessel Density on Non-Contrast Computed Tomography to Detect Basilar Artery Occlusion [PDF]
, 2020 Introduction: Basilar artery occlusion (BAO) may be clinically occult due to variable and non-specific symptomatology. We evaluated the qualitative and quantitative determination of a hyperdense basilar artery (HDBA) on non-contrast computed tomography ...
Asimos, Andrew W. +6 more
core
Chinese Journal of Contemporary Neurology and NeurosurgeryObjective To investigate the efficacy and safety of mechanical thrombectomy in patients with acute progressive ischemic stroke with large vessel occlusion in the anterior circulation.
HAN Ning +4 more
doaj +1 more source
Clot Composition Profiling in Large Vessel Occlusion Stroke Via Radiomics
Annals of Neurology, EarlyView.Objective Clot composition may offer insights into the mechanism of ischemic stroke. Radiomics, a noninvasive imaging technique, enables tissue characterization through radiomic features (RFs). We aimed to evaluate clot composition using radiomics on non‐contrast computed tomography (NCCT).
Andres Gudino +23 more
wiley +1 more source
Thrombus aspiration in patients with ST-elevation myocardial infarction: results of a national registry of interventional cardiology. [PDF]
, 2018 BACKGROUND: We aimed to evaluate the impact of thrombus aspiration (TA) during primary percutaneous coronary intervention (P-PCI) in 'real-world' settings.
Caldeira, D +5 more
core +1 more source