Results 81 to 90 of about 68,330 (260)

Individualized Treatment in Distal and Medium Vessel Occlusion Stroke Using a Validated Explainable Counterfactual Treatment Estimation Model

Annals of Neurology, EarlyView.
Objective The optimal treatment for distal medium vessel occlusion (DMVO) stroke remains uncertain, and evidence comparing endovascular therapy (EVT) with medical management (MM) is limited. We aimed to develop and validate a predictive modeling tool to assess individual treatment benefit in DMVO stroke using explainable counterfactual treatment ...
Mohamed F. Doheim, Mahmoud H. Mohammaden, Hend Abdelhamid, Marta Olive‐Gadea, Marc Rodrigo‐Gisbert, Manuel Requena, Johanna T. Fifi, James E. Siegler, Santiago Ortega‐Gutierrez, Mohamad Abdalkader, Ali Alaraj, Wei Hu, Thanh N. Nguyen, Diogo C. Haussen, Raul G. Nogueira   +14 more
wiley   +1 more source

Neuroimaging predictors of malignant brain oedema after thrombectomy in ischemic stroke: a systematic review and meta-analysis

Annals of Medicine
Background We systematically reviewed neuroimaging predictors for malignant brain oedema (MBE) after thrombectomy in patients with ischemic stroke.Methods We searched MEDLINE and EMBASE in November 2023 for studies of patients with ischemic stroke.
Linrui Huang, Xindi Song, Jingjing Li, Yanan Wang, Xing Hua, Meng Liu, Ming Liu, Simiao Wu   +7 more
doaj   +1 more source

Astrocytic Mitochondria Transplantation Rescues Neuron Loss and Dendritic Injuries in Acute Cerebral Ischemic Stroke Mouse Model by Flexibly Regulating Mitochondria Dynamics

Annals of Neurology, EarlyView.
Objective Cerebral ischemic stroke causes neuronal oxygen/energy deprivation, disrupting mitochondrial function including reduced membrane potential and bioenergetics, exacerbating neuronal injury. Mitochondrial defects are, therefore, a central neuropathological node and potential therapeutic target.
Ning Bian, Jianing Shen, Linwei Tian, Jinghui Li, Lu Yang, Bo Yuan, Shulin Li, Yuyu Niu, Lu Zhao, Jingkuan Wei   +9 more
wiley   +1 more source

Clinical selection strategies to identify ischemic stroke patients with large anterior vessel occlusion: results from SITS-ISTR (Safe Implementation of Thrombolysis in Stroke International Stroke Thrombolysis Registry) [PDF]

, 2017
Background and Purpose—The National Institutes of Health Stroke Scale (NIHSS) correlates with presence of large anterior vessel occlusion (LAVO). However, the application of the full NIHSS in the prehospital setting to select patients eligible for ...
Abdul-Rahim, Azmil H., Ahmed, Niaz, Audebert, Heinrich J., Broderick, Joseph P., Cooray, Charith, Endres, Matthias, Khatri, Pooja, Kleindorfer, Dawn, Lees, Kennedy R., MacIsaac, Rachael L., Nolte, Christian H., Scheitz, Jan F., Sucharew, Heidi, Wahlgren, Nils   +13 more
core   +2 more sources

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Initial Presentation of HIV Infection With Two Successive Acute Arterial Thromboses: A Case Report. [PDF]

, 2014
IntroductionOne of the complications of HIV infection is greater risk of thromboembolic events. A variety of mechanisms has been found to be responsible for prothrombotic tendency in patients with HIV infection.Case presentationA 27-year-old heterosexual
Moslemi, Sam, Tahamtan, Maryam, Ziaian, Bizhan   +2 more
core   +1 more source

Analysis of cholesterol crystals in thrombi obtained from endovascular treatment of acute ischemic stroke

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Objective To compare the difference of the rate of cholesterol crystals in thrombi obtained from patients of acute ischemic stroke with different etiologies and the effect of thrombi containing cholesterol crystals on vascular recanalization.
Zhao-yang SONG, Liang-fu ZHU, Tian-xiao LI, Kai-yan WU, Du-juan LI, Li-heng WU, Zhi-long ZHOU, Qiu-ji SHAO, Teng-fei ZHOU, Li-na WANG   +9 more
doaj   +1 more source

Management of symptomatic neonatal aortic thrombosis: When is surgery indicated?

Journal of Pediatric Surgery Case Reports, 2019
Neonatal aortic thrombosis is a rare but potentially life-threatening condition. Treatment is patient-specific and may include expectant management, therapeutic anticoagulation, systemic thrombolysis or surgical thrombectomy.
Bryan V. Dieffenbach, Bharath D. Nath, Elisabeth T. Tracy, Heung Bae Kim   +3 more
doaj   +1 more source

Advances and Prospects of Stereotactic Radiosurgery and Stereotactic Ablative Body Radiotherapy: Evolving Paradigms in Precision Oncology

Med Research, EarlyView.
The graphical abstract outlines the progressive development and impact of stereotactic radiosurgery (SRS) and stereotactic body radiotherapy (SBRT). Technological Evolution illustrates the transition from brachytherapy with single‐dose, LDR/HDR schedules to fractionated radiotherapy, three‐dimensional conformal radiotherapy (3DCRT) and Gamma Knife ...
Jing Zhang, Wenhao Xu, Weiqing Lu, Yingxuan Lin, Luoxi He, Zonglin Lv, Yiliyaer Nuerrula, Zouting, Zhen Zhang, Hailiang Zhang, Xuejun Ma   +10 more
wiley   +1 more source

Perfluorocarbon Enhanced Glasgow Oxygen Level Dependent (GOLD) magnetic resonance metabolic imaging identifies the penumbra following acute ischemic stroke [PDF]

, 2018
The ability to identify metabolically active and potentially salvageable ischaemic penumbra is crucial for improving treatment decisions in acute stroke patients.
Brennan, David, Deuchar, Graeme A., Holmes, William M., Macrae, I. Mhairi, Santosh, Celestine, Shaw, Martin   +5 more
core   +1 more source