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Results 141 to 150 of about 145,978 (310)

Reversible regulation of thrombin adsorption and desorption based on photoresponsive-aptamer modified gold nanoparticles

, 2015
In the protein separation, adsorption and desorption of target protein have been using different buffer condition. Different buffer will change the structure and activity of target protein in some cases.
Liangrong Yang +9 more
core +1 more source

The nature of thrombin and anti‐thrombin

The Journal of Physiology, 1913
B J, Collingwood, M T, Macmahon
openaire +3 more sources

Dual Action of Dipyridamole in Experimental Rheumatoid Arthritis: Suppression of Joint Inflammation and Upregulation of Muscle Anabolism via Adenosine and AMPK Pathways

Arthritis &Rheumatology, EarlyView.
Objective Rheumatoid sarcopenia, characterized by the progressive loss of skeletal muscle mass and function, is a frequent comorbidity in rheumatoid arthritis (RA), linked to prolonged, severe systemic inflammation. Purinergic signaling (adenosine, AMP, and ATP) plays a crucial role in inflammation, myogenesis, and muscle hypertrophy.
Miguel Marco‐Bonilla +13 more
wiley +1 more source

Boophilin inhibits thrombin.

, 2016
(A) Typical progress curves for thrombin-mediated hydrolysis of S2238 in the absence and presence of Boophilin at the indicated concentrations (a, 0 nM; b, 20 nM; c; 40 nM; d, 80 nM; e, 160 nM; f, 320 nM). Reactions started with addition of S2238 (250 μM)
Dongying Ma (132065) +7 more
core +1 more source

Higher Complement C4 Gene Copy Number Constitutes a Shared Genetic Risk Factor for Giant Cell Arteritis and IgA Vasculitis

Arthritis &Rheumatology, EarlyView.
Objective Low copy number (CN) of complement C4 isoforms and high CN of retroviral HERV‐K elements are known risk factors for many immune‐mediated inflammatory diseases (IMIDs), often showing sex‐biased effects. Here, we assessed whether CN variation within the C4 gene contributes to giant cell arteritis (GCA) and IgA vasculitis (IgAV), two complex ...
Laura Martínez‐Gutiérrez +295 more
wiley +1 more source

Thrombin generation tests

, 2011
The recent development of semi-automated methods has revived interest in the thrombin generation test, a global assay that measures the overall tendency of a plasma sample to form thrombin after initiation of coagulation.
Castoldi, Elisabetta +3 more
core +1 more source

Arthroscopic Implantation of Minced Cartilage From the Os Trigonum and Posterolateral Process of the Talus: Single‐Stage Cell‐Based Treatment of Osteochondral Lesion of the Talus

Arthroscopy Techniques, EarlyView.
Abstract The best surgical treatment of osteochondral lesion of the talus (OLT) remains controversial. Among the available surgical procedures for OLTs, implantation of the minced cartilage from the talar lesion is a promising cell‐based technique. However, surgeons may experience difficulties when enough volume and quality of the cartilage cannot be ...
Hélder Pereira, Takuji Yokoe
wiley +1 more source

Differences in the Effect of Antithrombin on Thrombin Clotting and Thrombin Esterase Activity

, 1969
SummaryFollowing the addition of thrombin to serum, thrombin clotting activity rapidly disappears. During the first half hour thrombin esterase activity also declines.
H Gans, A Boulton
core +1 more source

Design Space Assessment of Virus Inactivation in Plasma‐Derived Matrices Establishes a Single Detergent Alternative to TX‐100‐Containing Mixes

Biotechnology and Bioengineering, EarlyView.
ABSTRACT The detergent Triton X‐100 (TX‐100) is a typical component of solvent/detergent (S/D) mixes applied for virus inactivation steps of biomanufacturing processes, yet environmentally unfavorable properties have led to restrictions on its use. Deviron 13‐S9 has recently been described as an eco‐friendly TX‐100 alternative, with powerful virus ...
Johanna Kindermann +3 more
wiley +1 more source

Antiplatelet Effect of Marchantinquinone, Isolated from Reboulia Hemisphaerica, in Rabbit Washed Platelets

, 2009
Platelet activation is involved in serious pathological situations, including atherosclerosis and restenosis. It is important to find efficient antiplatelet medicines to prevent fatal thrombous formation during the course of these diseases ...
鄧哲明 +1 more
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blood coagulation
thrombosis
anticoagulants

fibrinogen
prothrombin
medicine