Results 211 to 220 of about 145,978 (310)

Haemostatic changes and bleeding with anti‐IL‐6 directed therapy in autoimmune diseases

British Journal of Pharmacology, EarlyView.
Abstract Anti‐IL‐6 directed therapy, especially tocilizumab (TCZ), is widely used for the treatment of autoimmune diseases such as rheumatoid arthritis, giant cell arteritis and systemic juvenile idiopathic arthritis. Next to being a master regulator of inflammation, IL‐6 also is an important regulator of haemostasis. Although generally well tolerated,
Charlotte D. C. C. van der Heijden, Loes C. Oskam, Lenny van Bon, Chantal P. Rovers   +3 more
wiley   +1 more source

Bothrops jararaca snake venom: A reappraisal of its coagulant activity in humans, mice, and rats. [PDF]

PLoS Negl Trop Dis
Torres AV, Penas Picon NT, Ferreira de Oliveira N, Sachetto ATA, Thomazini CM, de Albuquerque CZ, Mattaraia VGM, Santoro ML.   +7 more
europepmc   +1 more source

Open Questions in Surgery for Hepatoblastoma: A Joined SIOPEL‐IPSO Survey

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Surgery is pivotal in the management of hepatoblastoma (HB) although approaches and techniques may vary. The Liver Group of the International Society of Pediatric Oncology (SIOPEL) and the International Pediatric Surgical Oncology (IPSO) group collaborated to develop an online survey to investigate specific technical aspects and ...
Chiara Grimaldi, Francesca Gigola, Reto M. Baertschiger, Marco Del Riccio, Hanna Garnier, Gloria Gonzalez, York Tien Lee, Amos Loh, Luca Pio, Sophie Branchereau   +9 more
wiley   +1 more source

Intraoperative Agents for Hemostasis and Dural Reconstruction in Neurosurgery. [PDF]

Neurosurg Pract
Sibih YE, Haddad AF, Caldwell DJ, Aabedi AA, Yue JK.   +4 more
europepmc   +1 more source

Complement–Eosinophil Crosstalk Links Complement Activation to Fibrin Deposition in Eosinophilic Chronic Rhinosinusitis

Allergy, EarlyView.
Ryo Hasegawa, Shigeharu Ueki, Misaki Arima, Shohei Nishiyama, Keinosuke Hizuka, Kohei Tatsumi, Ayako Sawai, Anna Shimizu, Yuki Sonoda, Eiichi Kato, Masanori Kidoguchi, Masafumi Sakashita, Yohei Sato, Atsushi Kato, Bruce K. Tan, Robert C. Kern, Robert P. Schleimer, Shigeharu Fujieda, Yoshimasa Imoto   +18 more
wiley   +1 more source

Interstitial 11q Deletions and Terminal 11q Duplications Cause a Bleeding Tendency due to Platelet Dysfunction That Is Similar to 11q Deletions Causing Jacobsen Syndrome

European Journal of Haematology, EarlyView.
ABSTRACT Introduction Jacobsen syndrome, resulting from a terminal deletion of chromosome 11 (11q), may lead to an increased bleeding tendency due to low platelet counts or platelet dysfunction. Currently, information on bleeding tendency and platelet function in patients with nonterminal 11q‐aberrations such as larger deletions, interstitial 11q ...
Elise J. Huisman, Virgil A. S. H. Dalm, Marieke Joosten, Frans J. Smiers, Leendert Porcelijn, Arjan Hoogendijk, Hans Janssen, Nicole N. van der van der Wel, Idske C. L. Kremer Hovinga, Masja de Haas, Marjon H. Cnossen   +10 more
wiley   +1 more source

Analysis of the Phenotype and Gene Mutations of Two Families With Combined Mutations of Anticoagulant Protein Genes. [PDF]

Mol Genet Genomic Med
Guo Y, Shan T, Zheng W, Zhao C, Kong W, Zou X.   +5 more
europepmc   +1 more source

Interactions between small leucine‐rich proteoglycans and proteases: implications for tissue homeostasis and pathology

The FEBS Journal, EarlyView.
Small leucine‐rich proteoglycans (SLRPs) are key modulators of extracellular matrix structure and signaling. Their proteolytic processing by MMPs (Matrix Metalloproteinases), ADAMTS (disintegrin and metalloprotease with thrombospondin motifs), and serine proteases generates bioactive fragments that regulate collagen remodeling, inflammation, and ...
Maria Konstantaraki, Lydia‐Nefeli Thrapsanioti, Aikaterini Berdiaki, Ioanna Spyridaki, Dragana Nikitovic   +4 more
wiley   +1 more source

Concurrent femoral artery pseudoaneurysm and arteriovenous fistula following catheter ablation treated with selective coil embolization. [PDF]

Radiol Case Rep
Baracewicz J, Schaefer P.
europepmc   +1 more source