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Ex Vivo Effect of Apixaban on Hemostatic Biomarkers in Children With Heart Disease: A SAXOPHONE Trial Substudy. [PDF]

open access: yesJ Am Heart Assoc
Aborkhees GA   +14 more
europepmc   +1 more source
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Thrombin-activated thrombelastography for evaluation of thrombin interaction with thrombin inhibitors

Blood Coagulation & Fibrinolysis, 2007
For intravenous anticoagulation, heparin has been the mainstay drug, but its use may be contraindicated in heparin-induced thrombocytopenia and thrombosis. Heparin alternatives including direct thrombin inhibitors are available, but clotting assays (e.g.
Taro, Taketomi   +4 more
openaire   +2 more sources

Thrombin and acetylated thrombin in the activation of fibrinolysis

Canadian Journal of Physiology and Pharmacology, 1968
Thrombin that has been acetylated on its free amino group loses its fibrinogen-clotting properties, but when injected intravenously produces a fibrinolytic syndrome. The lytic results compare very closely to those obtained with thrombin administration, but acetylated thrombin does not produce fibrin deposition.
R H, Landaburu   +2 more
openaire   +2 more sources

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