Results 271 to 280 of about 145,978 (310)
Some of the next articles are maybe not open access.
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2012
Thrombin is the final protease generated in the blood coagulation cascade. It has multiple substrates and cofactors, and serves both pro- and anti-coagulant functions. How thrombin activity is directed throughout the evolution of a clot and the role of conformational change in determining thrombin specificity are issues that lie at the heart of the ...
openaire +2 more sources
Thrombin is the final protease generated in the blood coagulation cascade. It has multiple substrates and cofactors, and serves both pro- and anti-coagulant functions. How thrombin activity is directed throughout the evolution of a clot and the role of conformational change in determining thrombin specificity are issues that lie at the heart of the ...
openaire +2 more sources
Thrombin-soaked Coils: Estimation of Thrombin Dose
Journal of Vascular and Interventional Radiology, 1991Thrombin-soaked coils have been used as embolic agents for the treatment of various conditions. Intravascular injection of thrombin also has been used for thrombus formation; however, the effects of high doses of intravascular thrombin may be detrimental.
J T, Harman, G J, Becker
openaire +2 more sources
Blood, 1999
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire +3 more sources
We have investigated the influence of alterations in plasma coagulation factor levels between 50% and 150% of their mean values for prothrombin, factor X, factor XI, factor IX, factor VII, factor VIII, factor V, protein C, protein S, antithrombin III (AT-III), and tissue factor pathway inhibitor (TFPI) as well as combinations of extremes, eg, 50 ...
Butenas, S., van't Veer, C., Mann, K. G.
openaire +3 more sources
Chest, 2003
When the activities of the coagulation and fibrinolytic cascades are properly regulated, so that fibrin (FN) deposition and removal are properly balanced, the vascular system is protected from catastrophic blood loss at the site of an injury, while its fluidity is ensured elsewhere.
openaire +2 more sources
When the activities of the coagulation and fibrinolytic cascades are properly regulated, so that fibrin (FN) deposition and removal are properly balanced, the vascular system is protected from catastrophic blood loss at the site of an injury, while its fluidity is ensured elsewhere.
openaire +2 more sources
Canadian Journal of Biochemistry and Physiology, 1957
The enzymatic properties of thrombin have been examined and compared with those of two related enzymes, plasmin and trypsin. The effects of factors such as pH, substrate specificity, ionic strength, cations, anions, and organic reagents on the enzymatic activity of thrombin have been studied. While the three enzymes discussed possess differences, such
openaire +2 more sources
The enzymatic properties of thrombin have been examined and compared with those of two related enzymes, plasmin and trypsin. The effects of factors such as pH, substrate specificity, ionic strength, cations, anions, and organic reagents on the enzymatic activity of thrombin have been studied. While the three enzymes discussed possess differences, such
openaire +2 more sources
2011
Thrombosis is the most prevalent cause of fatal diseases in developed countries. An antithrombotic agent that can be administered to patients with severe acute thrombotic diseases without the risk of causing hemorrhage, as experienced with antithrombotic/thrombolytic therapy in the treatment of acute ischemic stroke or systemic anticoagulants like ...
openaire +2 more sources
Thrombosis is the most prevalent cause of fatal diseases in developed countries. An antithrombotic agent that can be administered to patients with severe acute thrombotic diseases without the risk of causing hemorrhage, as experienced with antithrombotic/thrombolytic therapy in the treatment of acute ischemic stroke or systemic anticoagulants like ...
openaire +2 more sources
Neurology, 2004
Not so long ago, events altering neurologic function were classified as “spells,” underscoring their cryptic nature. In time, many of these events were found to be ischemic strokes. That cerebral ischemia can be accompanied by alterations in the plasma is the basis for the hunt for convenient markers of brain injury that may suggest the cause.
openaire +1 more source
Not so long ago, events altering neurologic function were classified as “spells,” underscoring their cryptic nature. In time, many of these events were found to be ischemic strokes. That cerebral ischemia can be accompanied by alterations in the plasma is the basis for the hunt for convenient markers of brain injury that may suggest the cause.
openaire +1 more source
Thrombin‐Responsive Transcutaneous Patch for Auto‐Anticoagulant Regulation
Advanced Materials, 2017Yuqi Zhang, Jicheng Yu, Jinqiang Wang
exaly
Enhancement of incisional wound healing by thrombin conjugated iron oxide nanoparticles
Biomaterials, 2010Ofra Ziv-Polat +2 more
exaly