Results 181 to 190 of about 21,457 (218)
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Thrombocythemia as a Cause of Erythermalgia
Archives of Dermatology, 1977Erythermalgia is a distinctive clinical entity characterized by local redness, warmth, and burning pain in the distal portions of the extremities. In this study, erythemalgia was observed in two patients with myeloproliferative disease. A new theory suggesting abnormally rapid platelet aggregation as a cause of erythermalgia was advanced. The following
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Essential Thrombocythemia in an Infant
Journal of Pediatric Hematology/Oncology, 1996To report the unusual occurrence of essential thrombocythemia (ET) in a 5-month-old infant.The child was referred by her pediatrician for a high platelet count detected on routine blood testing. The child was asymptomatic except for failure to thrive. Diagnostic tests to rule out secondary causes of thrombocytosis as well as myeloproliferative syndrome
G, Kapoor, H, Correa, L C, Yu
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JAMA, 1965
EVEN BEFORE Nygaard's and Brown's inclusion of a patient with thrombocytosis in their series of five patients with "essential thrombophilia" in 1937, 1 scattered reports of patients with thrombohemorrhagic phenomena and increased numbers of circulating platelets had appeared in the English and foreign medical literature under such names as piastrinemia,
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EVEN BEFORE Nygaard's and Brown's inclusion of a patient with thrombocytosis in their series of five patients with "essential thrombophilia" in 1937, 1 scattered reports of patients with thrombohemorrhagic phenomena and increased numbers of circulating platelets had appeared in the English and foreign medical literature under such names as piastrinemia,
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Familial essential thrombocythemia
The American Journal of Medicine, 1986Primary or essential thrombocythemia is rarely observed in childhood, and familial occurrence has been reported only once. In this study, essential thrombocythemia is documented in five members of both sexes from two to 62 years of age in three successive generations.
M E, Eyster +6 more
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Primary or Hemorrhagic Thrombocythemia
Archives of Internal Medicine, 1968Fifteen patients with primary thrombocythemia were seen at the Mayo Clinic from 1960 through 1966. Nine patients presented with hemorrhagic manifestations, especially gastrointestinal bleeding. Three patients presented with thrombotic phenomena, including one patient with the nephrotic syndrome. Platelet counts in excess of 1 million/cu mm were seen in
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Management of Essential Thrombocythemia
Hematology, 2011Abstract Essential thrombocythemia (ET) is a Philadelphia chromosome (Ph)–negative myeloproliferative neoplasm (MPN) characterized by thrombocytosis and megakaryocytic hyperplasia of the bone marrow, with presence of the JAK2 V617F mutation in 50%-60% of patients. ET evolves to myelofibrosis in a minority of cases, whereas transformation
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Thrombocythemia and Neurologic Effects
Annals of Internal Medicine, 1984Excerpt To the editor: Jabaily and colleagues have (1) attributed neurologic manifestations in patients with essential thrombocythemia to elevated platelet levels.
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The pathogenesis of essential thrombocythemia
Current Opinion in Hematology, 2011The identification of new mutations continues to further our understanding of the molecular pathogenesis of essential thrombocythemia and related disorders, and offers opportunities for improvements in diagnosis, risk stratification and disease classification.Molecular lesions in essential thrombocythemia affect two distinct pathways: cytokine ...
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Current management strategies for polycythemia vera and essential thrombocythemia
Blood Reviews, 2020Paola Guglielmelli +1 more
exaly