Results 121 to 130 of about 288,284 (303)
Fever with thrombocytopenia associated with a novel bunyavirus in China.
New England Journal of Medicine, 2011 BACKGROUND Heightened surveillance of acute febrile illness in China since 2009 has led to the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an unknown cause.
Xue-Jie Yu +45 more
semanticscholar +1 more source
Targeted Therapies in Myelofibrosis: Present Landscape, Ongoing Studies, and Future Perspectives
American Journal of Hematology, EarlyView.ABSTRACT Myelofibrosis (MF) is a myeloproliferative neoplasm that is accompanied by driver JAK2, CALR, or MPL mutations in more than 90% of cases, leading to constitutive activation of the JAK–STAT pathway. MF is a multifaceted disease characterized by trilineage myeloid proliferation with prominent megakaryocyte atypia and bone marrow fibrosis, as ...
Giuseppe G. Loscocco, Paola Guglielmelli
wiley +1 more source
Emerging Infectious Diseases, 2020 Serologic and molecular surveillance of serum collected from 152 suspected scrub typhus patients in Myanmar revealed Orientia tsutsugamushi of genotypic heterogeneity.
A. M. Win +11 more
semanticscholar +1 more source
Pathophysiology and Diagnosis of Drug-Induced Immune Thrombocytopenia
Journal of Clinical Medicine, 2020 Drug-induced immune thrombocytopenia (DITP) is a life-threatening clinical syndrome that is under-recognized and difficult to diagnose. Many drugs can cause immune-mediated thrombocytopenia, but the most commonly implicated are abciximab, carbamazepine ...
C. Vayne +5 more
semanticscholar +1 more source
Progress and challenges of mRNA vaccines
Interdisciplinary Medicine, Volume 1, Issue 1, January 2023., 2023 As the third‐generation nucleic acid vaccine, the Messenger RNA (mRNA) vaccine stimulates a specific immune response by introducing mRNA expressing the target antigen into the body through a specific delivery system and expressing the corresponding protein.
Liangru Lin +3 more
wiley +1 more source
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT Prenatal and neonatal presentations of multiple congenital anomalies are difficult to diagnose and are associated with an increased risk of lethality. The differential diagnosis of antenatal presentations of radial ray malformations includes Fanconi anemia (FA), an inherited bone marrow failure disorder associated with congenital anomalies in ...
Ethan M. Scott +5 more
wiley +1 more source
PLoS Pathogens, 2019 Dengue virus (DENV) infection, the most common mosquito-transmitted viral infection, can cause a range of diseases from self-limiting dengue fever to life-threatening dengue hemorrhagic fever and shock syndrome. Thrombocytopenia is a major characteristic
Chiao-Hsuan Chao +6 more
semanticscholar +1 more source
Incidence and risk factors of neonatal thrombocytopenia: a pr
Paediatrica Indonesiana, 2010 Background Thrombocytopenia is the most common hematological abnormality in the neonatal period. Hemorrhagic manifestations are found in 10% cases of thrombocytopenia.
Nila Kusumasari +3 more
doaj +1 more source
Prenatal Brain Abnormalities in Sodium‐Dependent Multivitamin Transporter Deficiency
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT In treatable neurometabolic disorders, early diagnosis and prompt initiation of treatment are key to improved survival and outcomes. Biallelic variants in SLC5A6 cause sodium‐dependent multivitamin transporter deficiency (OMIM # 618973), which is treatable with high‐dose pantothenic acid, biotin, and alpha lipoic acid.
Eri Ogawa +2 more
wiley +1 more source
Annals of Neurology, EarlyView.Objective To compare clinical and radiological outcomes among relapsing multiple sclerosis patients treated with autologous hematopoietic stem cell transplantation (AHSCT), alemtuzumab (ATZ), and ocrelizumab (OCR). Methods From a London (UK) hospital‐based observational cohort, modeled data were obtained from 621 relapsing–remitting multiple sclerosis ...
Paolo Antonio Muraro +16 more
wiley +1 more source