Results 121 to 130 of about 409,848 (384)

PATHOBIOLOGY AND TREATMENT OF HEPATITIS VIRUS-RELATED THROMBOCYTOPENIA

Mediterranean Journal of Hematology and Infectious Diseases, 2009
Thrombocytopenia is a well recognized complication of infections, including those from hepatotropic viruses. Thrombocytopenia may actually be the only manifestation of vital hepatitis, which should therefore be considered in the differential diagnosis of
Roberto Stasi, Lian Wea Chia, Pallavi Kalkur, Robert Lown, Muriel S. Shannon   +4 more
doaj   +1 more source

Modern concepts of the platelet in health and disease [PDF]

, 1962
Thesis (M.D.)--Boston ...
Estes, J. Worth
core  

Eltrombopag for the treatment of immune thrombocytopenia: The aegean region of Turkey experience [PDF]

, 2015
Objective: Immune thrombocytopenia (ITP) is an immune-mediated disease characterized by transient or persistent decrease of the platelet count to less than 100x109/L. Although it is included in a benign disease group, bleeding complications may be mortal.
Alacacıoğlu, İ., Arslan, Ö., Bilgir, O., Bolaman, Z., Büyükkeçeci, F., Ceylan, C., Gökgöz, Z., Görgün, G., Kabukçu, Sibel, Kadıköylü, G., Kahraman, S., Keskin, A., Kiper, H.D., Payzın, B., Saydam, G., Sevindik, Ö.G., Tombuloğlu, M., Vural, F., Çağlıyan, G.A., Özcan, M.A., Özdemirkıran, F., Şahin, F.   +21 more
core   +4 more sources

Pathogenesis and Therapeutic Mechanisms in Immune Thrombocytopenia (ITP)

Journal of Clinical Medicine, 2017
Immune thrombocytopenia (ITP) is a complex autoimmune disease characterized by low platelet counts. The pathogenesis of ITP remains unclear although both antibody-mediated and/or T cell-mediated platelet destruction are key processes.
A. Zufferey, R. Kapur, J. Semple
semanticscholar   +1 more source

Practical guidance for the management of adults with immune thrombocytopenia during the COVID‐19 pandemic

British Journal of Haematology, 2020
This document aims to provide practical guidance for the assessment and management of patients with thrombocytopenia, with a particular focus on immune thrombocytopenia (ITP), during the COVID‐19 pandemic.
S. Pavord, J. Thachil, B. Hunt, M. Murphy, G. Lowe, M. Laffan, M. Makris, A. Newland, D. Provan, J. Grainger, Q. Hill   +10 more
semanticscholar   +1 more source

Exosomal CMTM4 Induces Immunosuppressive Macrophages to Promote Ovarian Cancer Progression and Attenuate Anti‐PD‐1 Immunotherapy

Advanced Science, EarlyView.
In ovarian tumors with high CMTM4 expression, exosomes transfer CMTM4 to macrophages, upregulating ICAM1 and promoting M2 polarization via p65 nuclear translocation. This suppresses immunity by increasing PD‐1 and Tregs while reducing CD8+ T cells.
Bo Yin, Jianyi Ding, Jie Liu, Haoran Hu, Yashi Zhu, Meiqin Yang, Huijuan Zhou, Baoyou Huang, Tiefeng Huang, Mengjie Li, Yinyan He, Ang Li, Lingfei Han   +12 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

A Case of Thrombocytopenia due to Odontogenic Infection

Journal of Dental Research, Dental Clinics, Dental Prospects, 2011
Thrombocytopenia in surgical patients is a potentially serious condition, faced by surgeons. A close relationship between sepsis and thrombocytopenia has been suggested.
Dinesh Kumar Verma, Ritesh Rajan
doaj  

Clinical and Laboratory Analysis of Children Who Follow Up with Thrombocytopenia: A Retrospective Study

Güncel Pediatri
Introduction: Platelets are cells that play an important role in the first phase of hemostasis, where the clot plug is formed. Disorders in the number or function of platelets can lead to bleeding.
Yasemin Denkboy Öngen, Birol Baytan
doaj   +1 more source

Rumpel-Leede phenomenon in a hypertensive patient due to mechanical trauma: a case report. [PDF]

, 2016
In this report, we present an interesting case of a patient with Rumpel-Leede phenomenon, a rare occurrence that can result in significant delays in medical treatment. This phenomenon is characterized by the presence of a petechial rash that results from
Hartley, A, Hayat, SA, Lim, PB
core   +2 more sources