Results 51 to 60 of about 409,848 (384)
Background Thrombocytopenia poses a risk of bleeding in patients with chronic coronary syndrome after coronary intervention. However, whether thrombocytopenia also increases the bleeding risk in patients with atrial fibrillation and chronic coronary ...
Raisuke Iijima+13 more
doaj +1 more source
Thrombocytopenia and thrombosis are prominent in coronavirus disease 2019 (COVID‐19), particularly among critically ill patients; however, the mechanism is unclear.
Izhac Nazy+6 more
semanticscholar +1 more source
Profiling and targeting HER2-positive breast cancer using trastuzumab emtansine. [PDF]
PurposeThis article reviews the mechanism of action of trastuzumab emtansine (T-DM1), existing clinical data relating to its use for human growth factor receptor 2 (HER2)-positive breast cancer, potential pathways of resistance, and ongoing studies ...
Hurvitz, Sara A+2 more
core +1 more source
Thrombocytopenia in Virus Infections
Thrombocytopenia, which signifies a low platelet count usually below 150 × 109/L, is a common finding following or during many viral infections. In clinical medicine, mild thrombocytopenia, combined with lymphopenia in a patient with signs and symptoms ...
M. Raadsen+5 more
semanticscholar +1 more source
Thrombocytopenia in pregnancy [PDF]
Thrombocytopenia is defined as a platelet count of less than 150 x 109/l. Normal pregnancy is generally thought not to affect the platelet count,' but it has been suggested that the normal range is lower in pregnancy, and that the count falls in the third trimester.2`4 This review concentrates on causes of thrombocytopenia with particular reference to ...
openaire +3 more sources
Diagnostics of thrombocytopenias [PDF]
Laboratory methods used for the diagnostics of thrombocytopenias are reviewed. Differential diagnosis is usually carried out between immune and hypoproductive forms of thrombocytopenia. Immune thrombocytopenias are caused by appearance in blood of antiplatelet abtibodies and accelerated destruction of platelets sensibilized by those antibodies, and ...
A V Mazurov+2 more
openaire +4 more sources
Treatment of drug-induced immune thrombocytopenias
Several therapeutic agents can cause thrombocytopenia by either immune-mediated or non-immune-mediated mechanisms. Non-immune-mediated thrombocytopenia is due to direct toxicity of drug molecules to platelets or megakaryocytes.
Irene Marini+3 more
doaj +1 more source
Gaucher Disease and Myelofibrosis: A Combined Disease or a Misdiagnosis? [PDF]
Background: Gaucher disease (GD) and primary myelofibrosis (PMF) share similar clinical and laboratory features, such as cytopenia, hepatosplenomegaly, and marrow fibrosis, often resulting in a misdiagnosis.
Cardarelli, L+5 more
core +1 more source
Vaccine campaigns are currently underway worldwide to combat the COVID-19 pandemic. The newly developed vaccines are highly effective with minimal adverse effects. Recently, the AstraZeneca vaccine has raised public alarm with concerns regarding the rare,
I. Nazy+9 more
semanticscholar +1 more source
Management of thrombocytopenia [PDF]
Thrombocytopenia is one of the most common hematologic disorders, characterized by an abnormally low number of platelets from multiple causes. The normal count of thrombocytes (platelets) is between 150,000 and 450,000 per microliter. The clinical expression of thrombocytopenia has broad variation from asymptomatic to life-threatening bleeding. Various
James B. Bussel, Marina Izak
openaire +3 more sources