Results 51 to 60 of about 409,848 (384)

Thrombocytopenia as a Bleeding Risk Factor in Atrial Fibrillation and Coronary Artery Disease: Insights From the AFIRE Study

open access: yesJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2023
Background Thrombocytopenia poses a risk of bleeding in patients with chronic coronary syndrome after coronary intervention. However, whether thrombocytopenia also increases the bleeding risk in patients with atrial fibrillation and chronic coronary ...
Raisuke Iijima   +13 more
doaj   +1 more source

Platelet‐activating immune complexes identified in critically ill COVID‐19 patients suspected of heparin‐induced thrombocytopenia

open access: yesJournal of Thrombosis and Haemostasis, 2021
Thrombocytopenia and thrombosis are prominent in coronavirus disease 2019 (COVID‐19), particularly among critically ill patients; however, the mechanism is unclear.
Izhac Nazy   +6 more
semanticscholar   +1 more source

Profiling and targeting HER2-positive breast cancer using trastuzumab emtansine. [PDF]

open access: yes, 2014
PurposeThis article reviews the mechanism of action of trastuzumab emtansine (T-DM1), existing clinical data relating to its use for human growth factor receptor 2 (HER2)-positive breast cancer, potential pathways of resistance, and ongoing studies ...
Hurvitz, Sara A   +2 more
core   +1 more source

Thrombocytopenia in Virus Infections

open access: yesJournal of Clinical Medicine, 2021
Thrombocytopenia, which signifies a low platelet count usually below 150 × 109/L, is a common finding following or during many viral infections. In clinical medicine, mild thrombocytopenia, combined with lymphopenia in a patient with signs and symptoms ...
M. Raadsen   +5 more
semanticscholar   +1 more source

Thrombocytopenia in pregnancy [PDF]

open access: yesPostgraduate Medical Journal, 1992
Thrombocytopenia is defined as a platelet count of less than 150 x 109/l. Normal pregnancy is generally thought not to affect the platelet count,' but it has been suggested that the normal range is lower in pregnancy, and that the count falls in the third trimester.2`4 This review concentrates on causes of thrombocytopenia with particular reference to ...
openaire   +3 more sources

Diagnostics of thrombocytopenias [PDF]

open access: yesTerapevticheskii arkhiv, 2018
Laboratory methods used for the diagnostics of thrombocytopenias are reviewed. Differential diagnosis is usually carried out between immune and hypoproductive forms of thrombocytopenia. Immune thrombocytopenias are caused by appearance in blood of antiplatelet abtibodies and accelerated destruction of platelets sensibilized by those antibodies, and ...
A V Mazurov   +2 more
openaire   +4 more sources

Treatment of drug-induced immune thrombocytopenias

open access: yesHaematologica, 2022
Several therapeutic agents can cause thrombocytopenia by either immune-mediated or non-immune-mediated mechanisms. Non-immune-mediated thrombocytopenia is due to direct toxicity of drug molecules to platelets or megakaryocytes.
Irene Marini   +3 more
doaj   +1 more source

Gaucher Disease and Myelofibrosis: A Combined Disease or a Misdiagnosis? [PDF]

open access: yes, 2018
Background: Gaucher disease (GD) and primary myelofibrosis (PMF) share similar clinical and laboratory features, such as cytopenia, hepatosplenomegaly, and marrow fibrosis, often resulting in a misdiagnosis.
Cardarelli, L   +5 more
core   +1 more source

Recommendations for the clinical and laboratory diagnosis of vaccine‐induced immune thrombotic thrombocytopenia (VITT) for SARS‐CoV‐2 infections: Communication from the ISTH SSC Subcommittee on Platelet Immunology.

open access: yes, 2021
Vaccine campaigns are currently underway worldwide to combat the COVID-19 pandemic. The newly developed vaccines are highly effective with minimal adverse effects. Recently, the AstraZeneca vaccine has raised public alarm with concerns regarding the rare,
I. Nazy   +9 more
semanticscholar   +1 more source

Management of thrombocytopenia [PDF]

open access: yesF1000Prime Reports, 2014
Thrombocytopenia is one of the most common hematologic disorders, characterized by an abnormally low number of platelets from multiple causes. The normal count of thrombocytes (platelets) is between 150,000 and 450,000 per microliter. The clinical expression of thrombocytopenia has broad variation from asymptomatic to life-threatening bleeding. Various
James B. Bussel, Marina Izak
openaire   +3 more sources

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