Results 71 to 80 of about 409,848 (384)

Vaccine-induced immune thrombotic thrombocytopenia: what we know and do not know

Blood, 2021
Development of vaccines to fight COVID19has been a remarkable medical achievement. However, this global immunization effort has been complicated by arare vaccine-related outcome characterized by thrombocytopenia and thrombosisin association with ...
G. Arepally, T. Ortel
semanticscholar   +1 more source

Thrombocytopenia-related outcome and pattern in preterm neonates hospitalized in neonatology unit: A single-center experience

Iraqi Journal of Hematology
BACKGROUNDS: In preterm newborns, thrombocytopenia is one of the most often observed hematologic findings. Most cases of thrombocytopenia are mild to moderate, self-limiting, and have a short duration; nevertheless, in rare cases, it can result in ...
Sambhav Jain, Bablu Kumar Gaur, Manish Sharma, Rupa Rajbhandari Singh   +3 more
doaj   +1 more source

Human platelets and their capacity of binding viruses: Meaning and challenges? [PDF]

, 2015
Blood platelets are first aimed at ensuring primary hemostasis. Beyond this role, they have been acknowledged as having functions in the maintenance of the vascular arborescence and, more recently, as being also innate immune cells, devoted notably to ...
Chabert, Adrien, Cognasse, Fabrice, Garraud, Olivier, Gomez, Ricardo Martin, Hamzeh Cognasse, Hind, Pozzetto, Bruno, Schattner, Mirta Ana   +6 more
core   +2 more sources

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Increased hs-CRP and Sepsis Influence the Occurrence of Thrombocytopenia in Severe and Critically Ill COVID-19 Patients Receiving Anticoagulants

Indonesian Biomedical Journal, 2023
BACKGROUND: Despites its benefits, as one of COVID-19 principal treatments, anticoagulant raises a significant concern regarding the anticoagulant-related thrombocytopenia.
Ami Ashariati Prayoga, Siprianus Ugroseno Yudho Bintoro, Pradana Zaky Romadhon, Muhammad Noor Diansyah, Putu Niken Ayu Amrita, Merlyna Savitri, Choirina Windradi, Krisnina Nurul Widiyastuti   +7 more
doaj   +1 more source

Intracranial haemorrhage in a dobermann puppy with von Willebrand's disease [PDF]

, 1995
Neurological examination of a lethargic, ataxic 12-week-old dobermann revealed decreased conscious proprioception in all its limbs. Haematological examination revealed a low platelet count.
Dunn, J.K., Dunn, K.J., Herrtage, M.E., Nicholls, P.K.   +3 more
core   +2 more sources

Neonatal thrombocytopenia

Seminars in Fetal and Neonatal Medicine, 2008
Neonatal thrombocytopenia is a common clinical problem. The majority of episodes are early-onset thrombocytopenias due to impaired fetal megakaryocytopoiesis associated with placental insufficiency; the commonest causes of severe early-onset thrombocytopenia are immune thrombocytopenias, congenital infections, and asphyxia.
Roberts, I, Murray, N
openaire   +4 more sources

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

How I approach new onset thrombocytopenia

Platelets, 2020
Thrombocytopenia is a common reason for referral to hematologists in community and hospital practice. A broad differential diagnosis, combined with the potentially life-threatening nature of some presentations necessitates a rapid evaluation of the ...
Fiona Swain, Robert Bird
doaj   +1 more source

NETosis and thrombosis in vaccine-induced immune thrombotic thrombocytopenia

Nature Communications, 2021
Vaccine-induced immune thrombotic thrombocytopenia (VITT) is a rare yet serious adverse effect of the adenoviral vector vaccines ChAdOx1 nCoV-19 (AstraZeneca) and Ad26.COV2.S (Janssen) against COVID-19.
H. Leung, J. Perdomo, Z. Ahmadi, S. Zheng, Fairooj N. Rashid, A. Enjeti, S. Ting, James J. H. Chong, B. Chong   +8 more
semanticscholar   +1 more source