Results 31 to 40 of about 13,951 (226)

Thromboelastography and thrombin generation assessments for pediatric severe hemophilia A patients are highly variable and not predictive of clinical phenotypes

Research and Practice in Thrombosis and Haemostasis, 2022
Background Severe hemophilia A (SHA) patients vary in severity of bleeding, arthropathy, and requirements for replacement factor VIII (FVIII). Baseline hemostatic activity assays using calibrated automated thrombography (CAT) and thromboelastography (TEG)
Natalie Mathews, Fred G. Pluthero, Margaret L. Rand, Ann Marie Stain, Manuel Carcao, Victor S. Blanchette, Walter H. A. Kahr   +6 more
doaj   +1 more source

Iron stores and coagulation parameters in patients with hypoxemic polycythemia secondary to chronic obstructive pulmonary disease: the effect of phlebotomies [PDF]

, 1997
This study was designed to determine the effects of phlebotomy on iron body contents and coagulation tests of COPD patients with polycythemia secondary to hypoxemia. Seventeen patients with COPD and hematocrits higher than 54 percent (mean Hct: 57 ± 0.49
Guerra, Celso Carlos de Campos, Jardim, José Roberto, Martinez, José Antônio Baddini, Nery, Luiz Eduardo   +3 more
core   +2 more sources

Co-Create Solutions: Innovate or Evaporate: the Value Driven PMO [PDF]

, 2019
Project Management Offices (PMOs) are commonplace in today’s technology-driven healthcare organizations. This case study is about a Middle Eastern PMO that was instrumental in opening a greenfield hospital and optimizing the services provided by the ...
Langston, Craig Ashley, Sherlock, Gareth, Skulmoski, Gregory James   +2 more
core   +1 more source

EFFECT OF SINGLE AND MULTIPLE IMPACT OF HYPOXIC HYPOXIA OF STRONG INTENSITY ON THE STATE OF THE HEMOSTATIC SYSTEM IN RATS

Сибирский научный медицинский журнал, 2019
The aim of the study was to analyze the state of the reaction of the hemostasis system in rats to a single and multiple exposures to hypoxic hypoxia of strong intensity. Material and methods. Male rats (40 individuals) of the Wistar line were used in the
S. V. Moskalenko, I. I. Shakhmatov, Y. A. Bondarchuk, O. M. Ulitina, O. V. Alekseeva   +4 more
doaj   +1 more source

Application of basic and composite thrombelastography parameters in monitoring of the antithrombotic effect of the low molecular weight heparin dalteparin: an in vivo study [PDF]

, 2009
Udgivelsesdato: 2009-nullABSTRACT: BACKGROUND: Low molecular weight heparin (LMWH) is in vast usage for treatment of thromboembolic diseases such as deep venous thrombosis and acute coronary syndromes.
Ramin RaminArtang, Niels J Frandsen, Jørn Dalsgaard Nielsen, Artang, Ramin   +3 more
core   +2 more sources

Identification of Coagulation Phenotypes Using Viscoelastic and Conventional Assays During Veno‐Venous Extracorporeal Membrane Oxygenation: A Hierarchical Clustering Analysis

Artificial Organs, EarlyView.
Hierarchical clustering of viscoelastic and conventional coagulation parameters identified three distinct phenotypes in V‐V ECMO patients, revealing substantial APTT–CK‐R discordance and highlighting the value of TEG‐derived markers for detecting coagulopathy not captured by standard monitoring.
Daisuke Irimada, Yudai Iwasaki, Yusuke Takei, Moe Oyama, Ami Tanaka, Shinichi Yamaguchi, Naoya Kobayashi, Daisuke Konno, Takuya Shiga, Masanori Yamauchi   +9 more
wiley   +1 more source

Glanzmann thrombasthenia and its perioperative management in head trauma: A rare and challenging situation

Journal of Neuroanaesthesiology and Critical Care, 2016
Glanzmann thrombasthenia is a rare inherited coagulation disorder, manifesting itself in early childhood as bleeding episodes. The patients with this disease may present with uncontrollable bleeding following trauma.
Neeraj Kumar, Abdul A. Khan, Nilesh Kumar, Ashish Bindra, Charu Mahajan, Keshav Goyal   +5 more
doaj   +1 more source

Aggregometry and thromboelastography to identify the timing to trach a COVID‐19 patient receiving both antiplatelet therapy and enoxaparin

Clinical Case Reports, 2021
In COVID‐19 patients receiving enoxaparin and antiplatelets therapy, aggregometry and thromboelastography might be considered an adjunctive tool to identify the time to perform procedures at risk of bleeding, such as tracheostomy.
Marco Tescione, Eugenio Vadalà, Graziella Marano, Andrea Bruni, Eugenio Garofalo, Ovidia Lavalle, Federico Longhini, Enzo Battaglia, Nicola Polimeni, Demetrio Labate, Sarah Caracciolo, Francesco Giordano, Massimo Caracciolo, Sebastiano Macheda   +13 more
doaj   +1 more source

Viscoelastic Testing in Pediatric Mechanical Circulatory Support

Frontiers in Medicine, 2022
Pediatric mechanical circulatory support can be lifesaving. However, managing anticoagulation is one of the most challenging aspects of care in patients requiring mechanical circulatory support.
Katherine Regling, Arun Saini, Katherine Cashen   +2 more
doaj   +1 more source

Altered cytoskeletal integrity underlies impaired platelet shape change and defective thrombus formation in ETV6‐related thrombocytopenia

British Journal of Haematology, EarlyView.
Summary ETV6‐related thrombocytopenia (ETV6‐RT) is an inherited platelet disorder caused by germline ETV6 variants. Despite recent progress, the mechanisms underlying platelet dysfunction in ETV6‐RT remain unclear. We investigated 12 patients from six families using functional assays, electron microscopy, quantitative proteomics and cytoskeletal ...
Ivan P. Tesakov, Julia‐Jessica D. Korobkin, Daria V. Fedorova, Sofia V. Galkina, Maria M. Golomysova, Sergei I. Obydennyi, Anastasia A. Ignatova, Ekaterina‐Iva A. Adamanskaya, Eugenia V. Yushkova, Anna V. Pavlova, Pavel A. Zharkov, Igor I. Kireev, Galina A. Novichkova, Viktor G. Zgoda, Mikhail A. Panteleev, Anastasia N. Sveshnikova   +15 more
wiley   +1 more source