Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel +5 more
wiley +1 more source
ABSTRACT Background Hormone Replacement Therapy (HRT) is used to manage menopausal symptoms, particularly vasomotor symptoms (VMS). HRT prescribing rates are rising, but most women will eventually discontinue. Objectives To explore the experiences of women stopping HRT, why women restart HRT, and the HCPs advising them. Search Strategy Embase, MEDLINE,
Sarah Bunnewell +4 more
wiley +1 more source
Factors Associated With Hormone Replacement Therapy Use: A Systematic Review and Meta‐Analysis
ABSTRACT Objective To identify factors associated with HRT uptake among women. Design A systematic review and meta‐analysis to identify factors associated with HRT uptake. Setting Retrospective and prospective cohort studies, case–control studies and cross‐sectional studies from any country and in any language. Population The study population was women
Wema Meranda Mtika +9 more
wiley +1 more source
Acute asymptomatic pulmonary thromboembolism detected using dynamic digital radiography following total hip arthroplasty: a case report. [PDF]
Hieda Y +4 more
europepmc +1 more source
Prevention of Hospital-Acquired Venous Thromboembolism (HA-VTE) Expert Panel Meeting: Meeting Summary [August 19, 2011] [PDF]
Revised April 30, 2012CS23243412_232434-a_sayers_ha-vte_workshop_report_508 ...
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ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong +5 more
wiley +1 more source
Pregnancy Outcomes Among Individuals With Cerebral Palsy: A Population‐Based Cohort Study
ABSTRACT Objective To examine the risks of maternal, neonatal and non‐obstetrical medical complications in individuals with cerebral palsy (CP) compared to those without CP. Design Population‐based cohort study. Setting Ontario, Canada. Population Females aged 13–54 years with a livebirth or stillbirth, 2004–2023.
Marina Vainder +3 more
wiley +1 more source
Risk of Stroke, Thromboembolism and Mortality in Atrial Fibrillation Patients Across Different Stages and Types of Heart Failure: A Retrospective Cohort Study. [PDF]
Gao Q +11 more
europepmc +1 more source
Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas +3 more
wiley +1 more source

