ABSTRACT Introduction Patients with von Willebrand disease (VWD) undergoing surgery require von Willebrand factor (VWF) and factor VIII (FVIII) supplementation for adequate haemostasis. Plasma‐derived clotting factor concentrates differ in their VWF:FVIII activity ratios: high‐ratio product (HRP, 10:1), intermediate‐ratio product (IRP, 2.4:1), and low ...
Zoë A. Gras +2 more
wiley +1 more source
Early Detection of Thromboembolism during Open Repair for Complex Aortoiliac Aneurysms Using Continuous Noninvasive Lower Limb Oximetry. [PDF]
Fukunaga N +7 more
europepmc +1 more source
Perioperative Management in Persons With Haemophilia on Rebalancing Therapies: A Narrative Review
ABSTRACT Introduction Perioperative management in haemophilia often requires on‐demand use of clotting factor concentrates (CFC) and/or bypassing agents. Rebalancing agents (fitusiran, concizumab, marstacimab) offer a novel approach to prophylaxis by modulating endogenous anticoagulant pathways to restore haemostatic balance.
Amanda M. Henderson +2 more
wiley +1 more source
ABSTRACT Aim In Fontan‐associated liver disease (FALD), chronic congestion often confounds conventional fibrosis markers, complicating surveillance for hepatocellular carcinoma (HCC). Although lymphatic dysfunction is fundamental to Fontan physiology, its contribution to hepatocarcinogenesis remains unclear.
Koji Imoto +14 more
wiley +1 more source
Cumulative Incidence of Venous Thromboembolism in Patients With Uterine Cancer. [PDF]
Sassine D +6 more
europepmc +1 more source
Cutaneous involvement by myeloid leukaemias: challenging cases with important implications
Myeloid leukaemias and precursors involving the skin are often challenging to diagnose with varied and overlapping clinical and histopathologic features. Nonetheless, they are critical for pathologists to recognize and accurately classify. This review discusses the clinical, histopathological and genetic features of myelodysplasia cutis (A) and ...
Alexandra C. Hristov
wiley +1 more source
Documented risk-based antithrombotic management and 30-day outcomes after endoscopic hemostasis for non-variceal upper gastrointestinal bleeding: a retrospective cohort study. [PDF]
Zhao X, Wang L, Li J.
europepmc +1 more source
Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller +11 more
wiley +1 more source
Seasonal Variation in Reporting of Venous Thromboembolism in a Spontaneous Adverse Event Reporting System: Analysis of the Japanese Adverse Drug Event Report Database. [PDF]
Tanaka H, Ishii T.
europepmc +1 more source

