Background and purpose To investigate the association of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) with post-thrombolysis early neurological outcomes including early neurological ...
Pengyu Gong+15 more
doaj +2 more sources
Association between the atherogenic index of plasma and the non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio with early neurological deterioration after thrombolysis [PDF]
BackgroundThe atherogenic index of plasma (AIP) and non-high-density lipoprotein cholesterol to high-density lipoprotein cholesterol ratio (NHHR) are newly developed markers of lipid and glucose metabolism.
Yan Jiang+9 more
doaj +2 more sources
Intraocular hemorrhage in patients misdiagnosed with central retinal artery occlusion treated with thrombolysis [PDF]
IntroductionThe diagnosis of acute central retinal artery occlusion (CRAO) is commonly delayed in emergency departments (ED) where ophthalmologists are rarely available for immediate consultation.
Daniel V. Adamkiewicz+14 more
doaj +2 more sources
An Explainable Two-Stage Machine Learning Model for Predicting the Post-Thrombolysis Complications in Stroke Patients: A Multi-Center Study [PDF]
Current tools for predicting the thrombolysis risk in patients after stroke exhibit limited event prediction in early post-thrombolysis hemorrhagic events. This highlights an unmet medical need to improve the tools for stroke management.
Hongling Zhu+23 more
doaj +2 more sources
Background Early reports from the COVID‐19 pandemic identified coronary thrombosis leading to ST‐segment–elevation myocardial infarction (STEMI) as a complication of COVID‐19 infection.
Ankeet S. Bhatt+11 more
doaj +1 more source
Assessing the effectiveness of primary angioplasty compared with thrombolysis and its relationship to time delay: a Bayesian evidence synthesis [PDF]
Background: Meta-analyses of trials have shown greater benefits from angioplasty than thrombolysis after an acute myocardial infarction, but the time delay in initiating angioplasty needs to be considered.
Abrams, Keith R.+6 more
core +4 more sources
BackgroundIMPROVE‐IT (Improved Reduction of Outcomes: Vytorin Efficacy International Trial) showed that adding the nonstatin ezetimibe to statin therapy further reduced cardiovascular events in patients after an acute coronary syndrome. In a prespecified
Eri Toda Kato+9 more
doaj +1 more source
Trends in stroke thrombolysis rate in Bosnia and Herzegovina: a hospital-based observation study [PDF]
Aim To assess trends in thrombolysis rates and door-to-needle times in University Hospital Mostar. Methods Data from the University Hospital Mostar Registry were used.
Marija Bender+4 more
doaj +1 more source
Influence of age on outcome from thrombolysis in acute stroke: a controlled comparison in patients from the Virtual International Stroke Trials Archive (VISTA) [PDF]
<p><b>Background and Purpose:</b> Thrombolysis for acute ischemic stroke in patients aged >80 years is not approved in some countries due to limited trial data in the very elderly.
Bluhmki, E.+4 more
core +1 more source
Relationship of blood pressure, antihypertensive therapy, and outcome in ischemic stroke treated with intravenous thrombolysis: retrospective analysis from Safe Implementation of Thrombolysis in Stroke-International Stroke Thrombolysis Register (SITS-ISTR) [PDF]
<p><b>Background and Purpose:</b> The optimal management of blood pressure (BP) in acute stroke remains unclear. For ischemic stroke treated with intravenous thrombolysis, current guidelines suggest pharmacological intervention if ...
Ahmed, N.+4 more
core +1 more source