Results 1 to 10 of about 68,939 (98)

European Stroke Organisation (ESO) guidelines on intravenous thrombolysis for acute ischaemic stroke

open access: yesEuropean Stroke Journal, 2021
Intravenous thrombolysis is the only approved systemic reperfusion treatment for patients with acute ischaemic stroke. These European Stroke Organisation (ESO) guidelines provide evidence-based recommendations to assist physicians in their clinical ...
E. Berge   +9 more
semanticscholar   +1 more source

Intravenous Thrombolysis in Patients With Ischemic Stroke and Recent Ingestion of Direct Oral Anticoagulants

open access: yesJAMA Neurology, 2023
Key Points Question Is the recent use of direct oral anticoagulants (confirmed ingestion within 48 hours) associated with increased risk of symptomatic intracranial hemorrhage following intravenous thrombolysis for ischemic stroke?
T. Meinel   +224 more
semanticscholar   +1 more source

Effect of Mechanical Thrombectomy Without vs With Intravenous Thrombolysis on Functional Outcome Among Patients With Acute Ischemic Stroke: The SKIP Randomized Clinical Trial.

open access: yesJournal of the American Medical Association (JAMA), 2021
Importance Whether intravenous thrombolysis is needed in combination with mechanical thrombectomy in patients with acute large vessel occlusion stroke is unclear.
Kentaro Suzuki   +29 more
semanticscholar   +1 more source

Thrombus Composition and Efficacy of Thrombolysis and Thrombectomy in Acute Ischemic Stroke

open access: yesStroke, 2021
Thrombi retrieved from patients with acute ischemic stroke are highly heterogeneous. Recent data suggest that thrombus composition may impact on mechanical thrombectomy, the number of recanalization manoeuvres, resistance to retrieval, and on ...
Precious Jolugbo, R. Ariëns
semanticscholar   +1 more source

The association of neutrophil to lymphocyte ratio, platelet to lymphocyte ratio, and lymphocyte to monocyte ratio with post-thrombolysis early neurological outcomes in patients with acute ischemic stroke

open access: yesJournal of Neuroinflammation, 2021
To investigate the association of neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR), and lymphocyte to monocyte ratio (LMR) with post-thrombolysis early neurological outcomes including early neurological improvement (ENI) and early
Pengyu Gong   +15 more
semanticscholar   +1 more source

Switching to Tenecteplase for Stroke Thrombolysis

open access: yesStroke, 2021
Supplemental Digital Content is available in the text. Background and Purpose: Due to practical advantages, increasing trial safety data, recent Australian Guideline endorsement and local population needs we switched to tenecteplase for stroke ...
K. Mahawish   +5 more
semanticscholar   +1 more source

Elaborately Engineering a Self‐Indicating Dual‐Drug Nanoassembly for Site‐Specific Photothermal‐Potentiated Thrombus Penetration and Thrombolysis

open access: yesAdvancement of science, 2021
Thrombotic cardio‐cerebrovascular diseases seriously threaten human health. Currently, conventional thrombolytic treatments are challenged by the low utilization, inferior thrombus penetration, and high off‐target bleeding risks of most thrombolytic ...
Zhiqiang Zhao   +12 more
semanticscholar   +1 more source

Thrombolysis with alteplase 3 to 4.5 hours after acute ischemic stroke.

open access: yesNew England Journal of Medicine, 2008
BACKGROUND Intravenous thrombolysis with alteplase is the only approved treatment for acute ischemic stroke, but its efficacy and safety when administered more than 3 hours after the onset of symptoms have not been established. We tested the efficacy and
W. Hacke   +13 more
semanticscholar   +1 more source

MRI‐Guided Thrombolysis for Stroke with Unknown Time of Onset

open access: yesNew England Journal of Medicine, 2018
Background Under current guidelines, intravenous thrombolysis is used to treat acute stroke only if it can be ascertained that the time since the onset of symptoms was less than 4.5 hours.
G. Thomalla   +41 more
semanticscholar   +1 more source

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke

open access: yesNew England Journal of Medicine, 2019
Background The time to initiate intravenous thrombolysis for acute ischemic stroke is generally limited to within 4.5 hours after the onset of symptoms.
Henry Ma   +44 more
semanticscholar   +1 more source
internal medicine
cardiology
anesthesia
plasminogen activator
thrombus
tissue plasminogen activator
thrombosis
engineering
urokinase
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