Results 111 to 120 of about 193,589 (341)

Using Tenecteplase for Acute Ischemic Stroke: What Is the Hold Up? [PDF]

, 2020
Alteplase is the only Food and Drug Administration-approved intravenous (IV) thrombolytic medication for acute ischemic stroke. However, multiple recent studies comparing tenecteplase and alteplase suggest that tenecteplase is at least as efficacious as ...
Ataya, Ramsey, Brea, Isabel, Zitek, Tony
core  

Potentiation of thrombus instability: a contributory mechanism to the effectiveness of antithrombotic medications [PDF]

, 2018
© The Author(s) 2018The stability of an arterial thrombus, determined by its structure and ability to resist endogenous fibrinolysis, is a major determinant of the extent of infarction that results from coronary or cerebrovascular thrombosis.
A Gast, AD Michelson, B Labarthe, B Shen, C Patrono, CT Ammollo, D Capodanno, D Gailani, DA Gorog, Diana A. Gorog, DM Coenen, E Álvarez, ER Bates, F Kabirian, F Müller, F Semeraro, G Stephens, H Brogren, HE Speich, HE Speich, HJ Weiss, HJ Weiss, HR Baumgartner, J Zilberman-Rudenko, JD McFadyen, JI Weitz, JM Cosemans, JP Collet, JP Collet, K Hosokawa, K Nagatsuka, KS Sakariassen, L Valerio, LF Brass, M Cattaneo, M Farag, M Humbert, M Larsson, M Li, M Ungerer, MA Bailey, MI Furman, MJ Price, ML Montfoort von, MS Sabatine, P Andre, P Seizer, PA Borne von dem, PP Wadowski, R Hellmuth, R Nergiz-Unal, RA Ajjan, S Goto, S Goto, SA Shaya, SB Larsen, SJ Marciniak, T Heitzer, T Renné, VT Turitto, VT Turitto, WA Schumacher, WS Nesbitt, X Wang, Y Yano, YC Lau, ZM Ruggeri   +66 more
core   +2 more sources

Higher Platelet-to-Lymphocyte Ratio Is Associated With Worse Outcomes After Intravenous Thrombolysis in Acute Ischaemic Stroke

Frontiers in Neurology, 2019
Objective: The platelet-to-lymphocyte ratio (PLR) is a new marker of atherosclerotic inflammation and has been identified as a predictive factor in cardiovascular diseases, but its significance in patients with acute ischaemic stroke (AIS) who have ...
Jing Xu, Xin He, Qiang Li, Jian-Ren Liu, Mei-Ting Zhuang, F. Huang, Guanshui Bao   +6 more
semanticscholar   +1 more source

Prognostic impact of SCAI shock severity classes in AMI‐related cardiogenic shock: A sub‐study of the ECLS‐SHOCK Trial

ESC Heart Failure, EarlyView.
Patients with AMI‐CS (lactate >3 mmol/L) enrolled in the multicentre, randomized ECLS‐SHOCK trial were included. From a total of 417 patients, 51.6% (n = 215), 13.4% (n = 56) and 35.0% (n = 146) presented in SCAI Stages C, D and E, respectively. SCAI stages were associated with the risk of 30 day all‐cause mortality, with rates of renal replacement ...
Janine Pöss, Jacob Jentzer, Steffen Desch, Hans‐Josef Feistritzer, Anne Freund, Michelle Roßberg, Christian Jung, Taoufik Ouarrak, Steffen Schneider, Ibrahim Akin, Tienush Rassaf, Tharusan Thevathasan, Uwe Zeymer, Holger Thiele   +13 more
wiley   +1 more source

A cross sectional study on thrombolysis in ST elevation myocardial infarction and its assessment with respect to ST segment resolution and time delay [PDF]

Al Ameen Journal of Medical Sciences
Background: ST elevation myocardial infarction is a leading cause of death in India. Several socio-economic factors lead to delay in seeking thrombolysis. Aims and Objectives: To analyse the effect of time delay on the success of thrombolysis.
P.R. Bijeesh, Ahmed Altaf, Ruknuddin Sha, Ahmed Zahid   +3 more
doaj  

The interaction between policy and education using stroke as an example [PDF]

, 2008
This paper discusses the interaction between healthcare policy at the European, UK and Scottish levels and the funding of education that underpins specific health policy priorities.
Aiken, Aiken, Alberts, Booth, Byford, Chapman, Chapman, Charlton, Corea, Demaerschalk, Duncan, Elkins, Fang, Glen, Glen, Hacke, Hoban, LaMonte, Langhorne, Levine, Lindley, Lorraine N. Smith, Louise E. Craig, Matchar, Sandercock, Shiell, Stone, Warlow, Warlow   +28 more
core   +1 more source

Multi‐Cohort Analysis Reveals Genetic Predispositions to Clonal Hematopoiesis as Mutation‐Specific Risk Factors for Stroke

Advanced Genetics, Volume 6, Issue 1, March 2025.
This study comprehensively evaluated the differential effect of clonal hematopoiesis (CH) mutations on the risk of various stroke subtypes and functional recovery. It shows that TET2 is associated with small vessel stroke possibly via a pro‐inflammatory pathway. Abstract Recent observational studies have found an association between Clonal Hematopoesis
Shuyang Lin, Yang E. Li, Yan Wang
wiley   +1 more source

Apixaban Enhances Endogenous Fibrinolysis in Patients with Atrial Fibrillation [PDF]

, 2019
© The Author(s) 2019. Published by Oxford University Press on behalf of the European Society of Cardiology.AIMS: Approximately 20% of ischaemic stroke patients exhibit spontaneous arterial recanalization, attributable to endogenous fibrinolysis, which ...
Arachchillage, Deepa RJ, Farag, Mohamed, Gorog, Diana, Gue, Ying X., Lip, Gregory Y H, Spinthakis, Nikolaos, Srinivasan, Manivannan, Wellsted, David   +7 more
core   +3 more sources

Markers of Coagulation and Fibrinolysis Predicting the Outcome of Acute Ischemic Stroke Thrombolysis Treatment: A Review of the Literature

Frontiers in Neurology, 2019
Intravenous administration of recombinant tissue plasminogen activator (rt-PA) has been proven to be safe and effective in the treatment of acute ischemic stroke.
Z. Bagoly, I. Szegedi, Rita Kálmándi, N. Tóth, L. Csiba   +4 more
semanticscholar   +1 more source

Noncontact Monitoring and AI‐Driven Stroke Prediction: National Center for Neurological Disorders‐Based Approach Using Smart Beds

Health Care Science, EarlyView.
The burden of stroke is extremely heavy. Current prehospital tools are not suitable for identifying stroke while a patient is asleep. This study successfully identified strokes by combining three types of easily accessible temporal and static features in hospitals.
Lan Lan, Jia‐Wei Luo, Rui Li, Ling Guan, Xin Wang, Jin Yin, Yi‐Long Wang   +6 more
wiley   +1 more source