Ischemic Stroke and Traumatic Brain Injury: Epidemiology, Molecular Pathways, and Emerging Therapies
Schematic overview of secondary brain injury after ischemic stroke and traumatic brain injury. Both conditions trigger endothelial cell dysfunction, pericyte contraction, and upregulated AQP4 expression in astrocytic end‐feet, leading to blood–brain barrier disruption.
Mengzhao Feng +7 more
wiley +1 more source
Optimal Duration of Ultrasound-Facilitated Catheter-Directed Thrombolysis for Acute Pulmonary Embolism: A Retrospective Cohort Study. [PDF]
Lin YK +8 more
europepmc +1 more source
ABSTRACT Background and Purpose This study sought to develop and validate a predictive model integrating the Braden scale to forecast the recovery of activities of daily living (ADL) in patients with post‐stroke hemiplegia. Additionally, it aimed to evaluate the effectiveness of a comprehensive rehabilitation program.
Yuanyuan Zhu +6 more
wiley +1 more source
Door-to-Needle Optimization in Acute Ischemic Stroke: A Review of Rapid Emergency Department Interventions. [PDF]
Chaudhary F +3 more
europepmc +1 more source
Young Mice Exhibit Increased Relative Ventricular Remodeling After AMI—A Longitudinal CMR Study
Serial CMR demonstrated no age‐related aggravation of post‐MI remodeling, although old mice displayed larger baseline cardiac geometry and increased diastolic mass. ABSTRACT Cardiovascular diseases are the leading cause of mortality worldwide, with myocardial infarction (MI) contributing significantly to this burden.
Heiko Lemcke +13 more
wiley +1 more source
Epidemiology and Outcomes of Acute Pulmonary Embolism in Seychelles: A National Cohort Study With a Subgroup Analysis of Systemic Thrombolysis Efficacy and Safety in Intermediate-Risk Pulmonary Embolism. [PDF]
Hassanein MF +12 more
europepmc +1 more source
ABSTRACT Aim Childhood ischemic stroke is rare but causes substantial long‐term morbidity, and its heterogeneous aetiology complicates timely diagnosis and management. Methods We conducted a retrospective population‐based observational study using hospital data and chart review to describe diagnostics, treatment and outcomes of ischemic stroke in ...
Jussi V. Leinonen +8 more
wiley +1 more source
Ischaemic stroke is characterised by acute cerebrovascular occlusion and blood–brain barrier (BBB) breakdown. Our results indicated that the histone deacetylase inhibitor suberoylanilide hydroxamic acid (SAHA) ameliorated the loss of BBB integrity, changed the morphology of brain endothelial cells, increased the level of basement membrane and ...
Anikó Szecskó +14 more
wiley +1 more source
Medium and distal vessel occlusion stroke: Redefining the role of thrombectomy through technology, timing, and patient selection. [PDF]
Jerele C, Frol S, Chapot R, Zupan M.
europepmc +1 more source

