Results 151 to 160 of about 127,924 (293)

Stent Thrombosis: A Narrative Review From Pathophysiology to Therapy

Clinical Cardiology, Volume 49, Issue 4, April 2026.
Stent thrombosis remains a life‐threatening complication of PCI driven by complex interactions between stent design, procedural factors, thrombogenic milieu, and inflammation. This review integrates pathophysiological mechanisms with contemporary and emerging therapeutic strategies, highlighting optimized PCI, tailored antithrombotic therapy, and novel
Emanuele Cecchi, Andrea Grasso Granchietti, Ruggero Mazzotta, Manuel Garofalo, Giorgia Panichella, Giuseppe Iula, Francesca Maria Di Muro, Silvia Menale, Rossella Marcucci   +8 more
wiley   +1 more source

Fibrinogen monitoring does not significantly reduce rates of bleeding complications during catheter-directed thrombolysis. [PDF]

CVIR Endovasc
Nguyen MA, Kaufman CS.
europepmc   +1 more source

Cystatin B Attenuates Cerebral Ischemia Reperfusion Injury by Inhibiting the JAK2/STAT3 Signaling Pathway

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Using experimental models of stroke, we demonstrate that Cystatin B (CSTB) alleviates brain injury following cerebral ischemia reperfusion. This protection is mediated by inhibiting the JAK2/STAT3 signaling pathway, which reduces neuroinflammation and neuronal apoptosis. Our findings highlight CSTB as a promising therapeutic target for ischemic stroke.
Gang Zhou, Fengjiao Hu, Ju Gao, Lei Wang, Xiangbo Wu, Yu Tian, Peng Zhang, Guangming Xia, Feng Wan, Jinhua Wang   +9 more
wiley   +1 more source

Electroacupuncture Modulates Multiple Pathways for Neuroprotection and Neurorepair in Ischemic Stroke

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
EA exerts therapeutic effects in ischemic stroke through multiple mechanisms: it alleviates acute injury by suppressing neuroinflammation, excitotoxicity, oxidative stress, apoptosis, pyroptosis, ferroptosis, autophagy dysregulation, and blood–brain barrier disruption, while enhancing cerebral blood flow, angiogenesis, and neurogenesis to support ...
Mingyue Zhao, Hangyu Shen, Xu Yan, Xiang Gao, Yuchun Liu, Shengjun Zhou, Jingxian Sun, Jie Sun, Yi Huang   +8 more
wiley   +1 more source

Thrombolytic Therapy in High-Risk Pulmonary Embolism with Thrombocytopenia: Case Report and Literature Review. [PDF]

J Clin Med
Boca MI, Cozlac AR, Streian CG, Crisan S, Lazar MA, Virtosu MD, Staicu RE, Iliescu D, Luca CT.   +8 more
europepmc   +1 more source

Decoding Post‐Stroke Cognitive Impairment After Acute Basal Ganglia Infarction: The Synergistic Role of Functional Segregation and Integration in an SVM fMRI Framework

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Post‐stroke cognitive impairment (PSCI) currently lacks reliable neuroimaging biomarkers for diagnosis. PSCI patients exhibit altered cerebellar‐cortical dynamics in PerAF, dALFF, and dFC, and an SVM classifier based on dFC features achieves 94.52% accuracy and 0.98 AUC, outperforming single‐metric models.
Shijian Chen, Jian Zhang, Liya Pan, Baohui Weng, Yijie Mo, Xuemei Quan, Gengyu Cen, Xize Jia, Yayuan Liu, Zhijian Liang   +9 more
wiley   +1 more source

Thrombolysis [PDF]

Journal of Vascular Surgery, 1994
openaire   +2 more sources

Thrombolysis for Obstructive HALT in Complex Valve-in-Valve TAVR. [PDF]

JACC Case Rep
Baudo M, Rahouma M.
europepmc   +1 more source

Diagnosis and management of transient ischaemic attack and ischaemic stroke in the acute phase [PDF]

, 2011
Dawson, J., McArthur, K.S., Quinn, T.J., Walters, M.R.   +3 more
core   +1 more source

Zinc Overload in Microvessels Contributes to Blood–Brain Barrier Disruption by Activating the JAK2 Pathway After Cerebral Ischemia/Reperfusion

CNS Neuroscience &Therapeutics, Volume 32, Issue 4, April 2026.
Cerebral ischemia/reperfusion (I/R) induces zinc accumulation in ischemic microvessels, activating Janus kinase 2/signal transducer (JAK2). This promotes mitochondrial translocation of phosphorylated STAT3 (p‐STAT3), leading to mitochondrial dysfunction that exacerbates endothelial cell death and disrupts blood–brain barrier (BBB).
Zhengran Guo, Wenjuan Shi, Xiaodong Chen, Shuhua Yuan, Xunming Ji, Zhifeng Qi   +5 more
wiley   +1 more source