Results 171 to 180 of about 127,924 (293)

Prognostic Implication of CYP2C19 Genotype According to Clinical Risk Stratification After Drug‐Eluting Stent Implantation

open access: yesClinical Pharmacology &Therapeutics, Volume 119, Issue 4, Page 928-941, April 2026.
From the nationwide multicenter consortium, 8,163 patients undergoing drug‐eluting stent implantation were classified according to the presence of the CYP2C19 loss‐of‐function (LoF) allele: rapid or normal metabolizers (RMs/NMs) vs. intermediate or poor metabolizers (IMs/PMs), and clinical risk was stratified using the CHADS‐P2A2RC and TRS 2°P scores ...
Hyun Woong Park   +22 more
wiley   +1 more source

Effectiveness of Knowledge Translation Strategies for Guideline Implementation: Protocol for an Update of an Overview of Systematic Reviews

open access: yesClinical and Public Health Guidelines, Volume 3, Issue 2, April 2026.
ABSTRACT Background Healthcare guidelines are necessary to optimise patient care and improve health outcomes; however, guidelines alone are insufficient to ensure changes in practice. This overview of reviews aims to identify, map and report on the effectiveness of knowledge translation (KT) strategies to implement guideline recommendations. Methods We
Kian Torabiardakani   +10 more
wiley   +1 more source

Ischemic Stroke Burden in China and Other G20 Nations (1990–2021): A Comparative Analysis From the Global Burden of Disease Study 2021 and Trend Projections Through 2031

open access: yesHealth Care Science, Volume 5, Issue 2, Page 141-157, April 2026.
This study analyzes ischemic stroke (IS) burden in China and other G20 countries (1990–2021) using Global Burden of Disease 2021 data. China exhibited rising age‐standardized incidence rates (ASIR: +12.6%) and delayed mortality decline, contrasting with G20 reductions (ASIR: −9.3%; sustained ASMR fall).
Bin Luo   +4 more
wiley   +1 more source

Different Approaches for Cerebral Angiography: Distal Radial Artery or Proximal Radial Artery? A Single‐Center, Non‐Blinded, Randomized Controlled Study

open access: yesHealth Science Reports, Volume 9, Issue 4, April 2026.
ABSTRACT Background and Aims As a safer approach for cerebral angiography, there is still a lack of further systematic research on the distal radial artery approach. To compare the safety and efficacy of the distal radial artery approach versus the conventional (proximal) radial artery approach for cerebral angiography, providing evidence for ...
Yuzheng Lai   +6 more
wiley   +1 more source

Early Versus Later Anticoagulation for Acute Ischemic Stroke in Patients With Atrial Fibrillation: A Systematic Review and Meta‐Analysis

open access: yesJournal of Arrhythmia, Volume 42, Issue 2, April 2026.
In patients with atrial fibrillation and acute ischemic stroke, early (≤ 4 days) initiation of direct oral anticoagulation was comparable to later (> 5 days) initiation for composite stroke outcomes and mortality. Stroke recurrence, bleeding risk, and survival did not significantly differ between strategies, supporting individualized timing decisions ...
Marwah Nasir Ahmad   +14 more
wiley   +1 more source

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