Is primary angioplasty cost effective in the UK? Results of a comprehensive decision analysis [PDF]
Objective: To assess the cost effectiveness of primary angioplasty, compared with medical management with thrombolytic drugs, to achieve reperfusion after acute myocardial infarction ( AMI) from the perspective of the UK NHS.
Abrams, Keith+6 more
core +2 more sources
Outcome of Repeated Thrombolysis in Debrecen Thrombolysis Database [PDF]
Recombinant tissue plasminogen activator (rtPA) is an efficient therapy of acute ischemic stroke. The risk of a recurrent ischemic stroke is high. This prospective single center study aimed to assess whether or not the repeated rtPA treatment is beneficial for acute stroke patients.All thrombolysed patients' data at the Department of Neurology ...
Fekete, Klára+3 more
openaire +3 more sources
Current Advancement and Patient Outcomes in Reperfusion Brain Injuries After Stroke: A Comparative Analysis of Thrombolysis and Thrombectomy. [PDF]
The graphical abstract illustrates how stroke‐induced reperfusion mitigates the brain injury and induces progressive brain damage. Early therapeutic or surgical intervention can be very beneficial to reduce stroke‐reperfusion‐induced brain damage. ABSTRACT Background Stroke remains a leading cause of death and disability worldwide, with ischemic stroke
Ayomide OT+9 more
europepmc +2 more sources
Minor stroke due to large artery occlusion. When is intravenous thrombolysis not enough? Results from the SITS International Stroke Thrombolysis Register [PDF]
Purpose: Beyond intravenous thrombolysis, evidence is lacking on acute treatment of minor stroke caused by large artery occlusion. To identify candidates for additional endovascular therapy, we aimed to determine the frequency of non-haemorrhagic ...
Ahmed, Niaz+11 more
core +1 more source
Multivariable analysis of outcome predictors and adjustment of main outcome results to baseline data profile in randomized controlled trials: Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) [PDF]
<p><b>Background and Purpose:</b> The Safe Implementation of Thrombolysis in Stroke-MOnitoring STudy (SITS-MOST) unadjusted results demonstrated that intravenous alteplase is well tolerated and that the effects were comparable with ...
Ahmed, Niaz+19 more
core +2 more sources
Compound porcine perebroside and ganglioside injection (CPCGI) was used to treat ischemic stroke. However, there was no clinical evidence of low‐dose CPCGI. We conducted a clinical study to analyze whether the clinical results of low‐dose and standard‐dose CPCGI in patients with ischemic stroke were different.
Ya Chen+8 more
wiley +1 more source
PRE-HOSPITAL THROMBOLYSIS IN KRASNOYARSK: RESULTS OF A RETROSPECTIVE COMPARATIVE STUDY
Aim. To compare the safety and efficacy of pre-hospital thrombolysis with tenecteplase and hospital thrombolysis with alteplase. Material and Methods. Pre-hospital thrombolytic therapy with tenecteplase (n=15) and hospital thrombolysis with alteplaza (n ...
S. A. Skripkin+4 more
doaj +1 more source
Objective To determine if rt ⁃ PA intravenous thrombolysis has distinct short ⁃ term effects on individuals of different ages with acute ischemic stroke.
WANG Jing, ZHANG Guo⁃fu
doaj +1 more source
Pulmonary embolism is a life-threatening condition treated with anticoagulation and systemic thrombolysis when appropriate. In patients with contraindications to thrombolysis, catheter-directed thrombolysis may be considered.
Steve M. Nelson, MD, Steven H. Craig, MD
doaj +1 more source
Background: Although intravenous (IV) thrombolysis is an effective treatment for patients with acute ischemic stroke (AIS), it remains underused by neurologists worldwide. This study assessed the knowledge and attitudes toward IV thrombolysis in patients
Fatimah Ali Alharbi+3 more
doaj +1 more source