Results 41 to 50 of about 147,480 (239)

Minor stroke due to large artery occlusion. When is intravenous thrombolysis not enough? Results from the SITS International Stroke Thrombolysis Register [PDF]

, 2017
Purpose: Beyond intravenous thrombolysis, evidence is lacking on acute treatment of minor stroke caused by large artery occlusion. To identify candidates for additional endovascular therapy, we aimed to determine the frequency of non-haemorrhagic ...
Ahmed, Niaz, Bar, Michal, Cooray, Charith, Ford, Gary A., Frol, Senta, Lees, Kennedy R., Mazya, Michael V., Moreira, Tiago, Sekaran, Lakshmanan, Toni, Danilo, Wahlgren, Nils, Švigelj, Viktor   +11 more
core   +1 more source

Using simulation and machine learning to maximise the benefit of intravenous thrombolysis in acute stroke in England and Wales: the SAMueL modelling and qualitative study

Health and Social Care Delivery Research, 2022
Background: Stroke is a common cause of adult disability. Expert opinion is that about 20% of patients should receive thrombolysis to break up a clot causing the stroke.
Michael Allen, Charlotte James, Julia Frost, Kristin Liabo, Kerry Pearn, Thomas Monks, Zhivko Zhelev, Stuart Logan, Richard Everson, Martin James, Ken Stein   +10 more
doaj   +1 more source

Clinical outcomes of submassive pulmonary embolism thrombolysis—an Indian experience

The Egyptian Heart Journal, 2020
Background Acute pulmonary thromboembolism is the most dangerous presentation of venous thromboembolic disease. The role of thrombolysis in massive pulmonary embolism has been studied extensively, but the same is not there for submassive pulmonary ...
Nadeem U. Rehman, Mohd Iqbal Dar, Manish Bansal, R. R. Kasliwal   +3 more
doaj   +1 more source

Metal–Organic‐Framework‐Derived Carbon Nanostructures for Site‐Specific Dual‐Modality Photothermal/Photodynamic Thrombus Therapy

Advanced Science, 2019
Although near‐infrared (NIR)‐light‐mediated photothermal thrombolysis has been investigated to overcome the bleeding risk of clinical clot‐busting agents, the secondary embolism of post‐phototherapy fragments (>10 µm) for small vessels should not be ...
Fengrong Zhang, Yuehong Liu, Jiani Lei, Shunhao Wang, Xunming Ji, Huiyu Liu, Qi Yang   +6 more
doaj   +1 more source

COST-EFFECTIVENESS EVALUATION OF PREHOSPITAL THROMBOLYSIS WITH TENECTEPLASE

Рациональная фармакотерапия в кардиологии, 2016
Aim. To evaluate clinical and cost effectiveness of different reperfusion strategies in myocardial infarction with ST segment elevation (STEMI), including pre-hospital thrombolysis with tenecteplase.  Material and methods.
V. V. Omel'yanovskiy, E. V. Derkach, P. M. Khaylov, S. N. Tereshchenko   +3 more
doaj   +3 more sources

Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]

, 2016
Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core   +2 more sources

Evaluation of real-world use of pulmonary embolism thrombolysis: ERUPT

ERJ Open Research
Introduction International guidelines recommend systemic thrombolysis for high-risk acute pulmonary embolism (PE). Significant uncertainties remain regarding thrombolysis in non-high-risk PE and the use of reduced-dose thrombolysis.
Ruth Sobala, Joseph Kibbler, Kay Yip, Ross Thompson, Cecillia Rafique, Matthew Steward, Romit Samanta, Akhilesh Jha, Najib Rahman, Anthony De Soyza, INSPIRE ERUPT collaborators, Jonathan Ayling-Smith, Alexandra Dipper, Delia Dorrian, Frances Grudzinska, Jo Hardy, Thomas Jones, Joseph Kibbler, Lola Loewenthal, Victoria Randles, Alex Teagle, Shaun Thein, Aki Jha, Hannah Carlin, Charlotte Holland, Arun-Brahmanya Prasad, Syed Jawad Ahmad, Hussain Basheer, Katie Burke, Alison Carter, Roisin Connon, Kennedy Edwards, Nehemiah Edwards, Thomas Fretwell, Freddy Frost, Fern Galhighay, Anita Golash, Sushant Goyal, Bipima Gurung, David Henshall, James Hyman, Daniel Mitchell, Philip Jones, Ghulam Haider Khan, Leila Mohammadi, Sarmad Mushtaq, Iftikhar Nadeem, Oghenevwed Anderson Okuma, Alasdair Phillips, Ben Pippard, Kay Protheroe, Jonathan Quinn, Victoria Randles, Shiva Sathanandam, Amina Yousuf Shaikh, Vikram Singh, Krishna Sivakumaran, Wojciech Slusarczyk, Katherine Smethurst, Asmah Syed, Richard Thorley, Hazel Watchorn, David Wilkinson   +62 more
doaj   +1 more source

Intravenous thrombolytic therapy for acute ischemic stroke in Hubei, China: a survey of thrombolysis rate and barriers

BMC Neurology, 2019
Background Rates of thrombolysis in most countries are well below best practice benchmarks. We aimed to investigate thrombolysis utilization and its associated factors in acute ischemic stroke (AIS) patients in Hubei province, China, to assess ...
Yanfeng Zhou, Shijiao Yan, Xingyue Song, Yanhong Gong, Wenzhen Li, Mengdie Wang, Xiaoxv Yin, Bo Hu, Zuxun Lu   +8 more
doaj   +1 more source

Predictors for cerebral edema in acute ischemic stroke treated with intravenous thrombolysis [PDF]

, 2017
Cerebral edema (CED) is a severe complication of acute ischemic stroke. There is uncertainty regarding the predictors for the development of CED after cerebral infarction.
Ahmed, Niaz, Azevedo, Elsa, Dawson, Jesse, Egido, Jose A., Falcou, Anne, Ford, Gary A., Holmin, Staffan, Mikulik, Robert, Ollikainen, Jyrki, Thorén, Magnus, Wahlgren, Nils   +10 more
core   +1 more source

Coronary Thrombolysis

Chest, 1989
Cairns, J, Collins, R, Fuster, V, Passamani, E   +3 more
  +9 more sources