Meta-Analysis of Predictive Role of Early Neurological Deterioration after Intravenous Thrombolysis
With the popularization of intravenous thrombolysis, more and more people use intravenous thrombolysis to treat related diseases, but problems also arise. There are still a considerable number of patients with early disease after thrombolytic therapy not
Haiwei Jiang +5 more
doaj +1 more source
"Sudden Drop" in Blood Pressure is Associated With Recanalization After Thrombolysis. [PDF]
We aim to investigate whether the phenomenon of "sudden drop" in blood pressure (BP) within the first 2 hours is associated with vessel recanalization.We retrospectively examined clinical and imaging data from a consecutive series of patients with stroke
Cao, Jin +4 more
core +1 more source
Effects of thrombolysis on outcomes of patients with deep venous thrombosis: An updated meta-analysis. [PDF]
BACKGROUND:Small randomized controlled studies and meta-analyses have shown that thrombolysis, especially catheter-directed thrombolysis, can reduce the incidence of post-thrombotic syndrome (PTS).
Zhenhua Xing +3 more
doaj +1 more source
Neuroimaging as a selection tool and endpoint in preclinical and clinical trials [PDF]
Standard imaging in acute stroke enables the exclusion of non-stroke structural CNS lesions and cerebral haemorrhage from clinical and pre-clinical ischaemic stroke trials. In this review, the potential benefit of imaging (e.g., angiography and penumbral
Macrae, I. Mhairi, Muir, Keith W.
core +2 more sources
Background: A number of large trials have confirmed the benefits of thrombolysis in acute stroke, but there are gender differences. We sought to examine the relationship between sex and outcome after thrombolysis.
José Luis Clua-Espuny +8 more
doaj +1 more source
Objective To determine if rt ⁃ PA intravenous thrombolysis has distinct short ⁃ term effects on individuals of different ages with acute ischemic stroke.
WANG Jing, ZHANG Guo⁃fu
doaj +1 more source
Stroke with unknown time of symptom onset: baseline clinical and magnetic resonance imaging data of the first thousand patients in WAKE-UP (efficacy and safety of mri-based thrombolysis in wake-up stroke: a randomized, doubleblind, placebo-controlled trial) [PDF]
Background and Purpose—We describe clinical and magnetic resonance imaging (MRI) characteristics of stroke patients with unknown time of symptom onset potentially eligible for thrombolysis from a large prospective cohort.
Boutitie, Florent +18 more
core +2 more sources
Intravenous Thrombolysis With Tenecteplase in Patients With Large Vessel Occlusions
Supplemental Digital Content is available in the text. Background and Purpose: Accumulating evidence from randomized controlled clinical trials suggests that tenecteplase may represent an effective treatment alternative to alteplase for acute ischemic ...
A. Katsanos +11 more
semanticscholar +1 more source
Effects of alteplase for acute stroke according to criteria defining the European Union and United States marketing authorizations: individual-patient-data meta-analysis of randomized trials [PDF]
Background: The recommended maximum age and time window for intravenous alteplase treatment of acute ischemic stroke differs between the Europe Union and United States.
Colin Baigent +28 more
core +5 more sources
Background Epistaxis is common with antithrombotic therapy and is often troublesome to patients, yet its frequency, severity, and outcomes are poorly characterized.
Robert S. Semco +9 more
doaj +1 more source

