Results 41 to 50 of about 2,550,374 (236)

Safety of alteplase intravenous thrombolysis and influencing factors of clinical outcome in elderly patients with acute ischemic stroke

BMC Neurology
Objective To explore the safety of intravenous thrombolysis with alteplase (rt-PA) in the treatment of acute ischemic stroke (AIS) in the elderly (≥ 80 years old) and with analyze the influencing factors of its clinical outcome.
Yongyin Zhang, Lifen Chi, Hao Shu, Qiang Zhou, Shunkai Zhang, Xuerong Huang, Xiaoyi Song   +6 more
doaj   +1 more source

Logistic regression analysis of recanalization after 120 min thrombolytic therapy.

, 2016
Logistic regression analysis of recanalization after 120 min thrombolytic therapy.
Lina Guan (396341), Yanping Zhu (367304), Yuming Mu (3608174)   +2 more
core   +1 more source

THROMBOLYTIC THERAPY OF ACUTE MYOCARDIAL INFARCTION [PDF]

, 2015
Importance of thrombolytic therapy for restoration of coronary blood flow in acute myocardial infarction is emphasized. Indications and contraindications, advantages and disadvantages for thrombolysis therapy are discussed.
D. P. Sementsov
core   +1 more source

Electronic Chip‐Mimetic Medical Implants for Controllable Sonothermal Treatments

Advanced Science, EarlyView.
Inspired by the thermal effect of working electronic chips, which consist of various heterostructures, an sonothermal‐responsive platform has been developed through constructing metal‐semiconductor interface on implants. Biofilm infection and deep vein thrombosis can be successfully treated by controllable ultrasound treatments.
Zhengdong Zhang, Pan Liu, Jie Lei, Shuchang Peng, Qiu Chen, Wei Guan, Yizhou Zhu, Gang Liu, Xiaobo Feng, Cao Yang, Lei Tan   +10 more
wiley   +1 more source

In silico assessment of histotripsy-induced changes in catheter-directed thrombolytic delivery

Frontiers in Physiology, 2023
Introduction: For venous thrombosis patients, catheter-directed thrombolytic therapy is the standard-of-care to recanalize the occluded vessel. Limitations with thrombolytic drugs make the development of adjuvant treatments an active area of research ...
Kenneth B. Bader, Katia Flores Basterrechea, Samuel A. Hendley   +2 more
doaj   +1 more source

Extracellular Vesicle Packaged TDP43 Derived From ECs Exacerbates Cigarette Tar‐Related Atherosclerosis Progression via Enhancing Macrophage Extracellular Traps

Advanced Science, EarlyView.
Cigarette tar triggers EC‐derived EVs carrying TDP43, which binds VDAC1 to boost MAMs, mitochondrial Ca2+ overload, and METs formation in macrophages, accelerating smoking‐related AS progression, while retinoic acid binds TDP43 to block this pathogenic cascade.
Xinxin Zhu, Yuwu Chen, Wei Meng, Biyi Xu, Junke Mou, Xiaolin Liu, Mengyang Wang, Qishuo Gu, Qianhui Sun, Man Li, Chen Zhao, Ming Zeng, Ying Lv, Boling Yi, Sheng Qu, Xiaoxuan Bai, Ji Li, Xing Luo, Sining Hu, Bo Yu, Haibo Jia   +20 more
wiley   +1 more source

Thrombolytic therapy in review

The Journal of Emergency Medicine, 1993
The use of thrombolytic agents for both coronary and noncoronary indications is a rapidly progressing field. There has been substantial debate over which disease processes ultimately benefit from the use of thrombolytic agents. In addition, many recent studies have focused on comparing different thrombolytic agents and dosing regimens in an attempt to ...
Department of Emergency Medicine, East Carolina University School of Medicine/ University Medical Center of Eastern Carolina, Greenville, North Carolina, USA ( host institution ), Thomas, Stephen H. ( author ), Shepherd, Suzanne M. ( author ), Allison, E.Jackson ( author )   +3 more
openaire   +3 more sources

Development of a decision analytic model to support decision making and risk communication about thrombolytic treatment [PDF]

, 2015
Background Individualised prediction of outcomes can support clinical and shared decision making. This paper describes the building of such a model to predict outcomes with and without intravenous thrombolysis treatment following ischaemic stroke ...
Ford, Gary, Thomson, Richard G., Gray, Jo, Richard G. Thomson, Jo Gray, Flynn, Darren, Darren Flynn, Rodgers, Helen, Peter McMeekin, Helen Rodgers, Gray, Joanne, Ford, Gary A., Thompson, Richard G., McMeekin, Peter, Gary A. Ford   +14 more
core   +2 more sources

Animal stroke models and outcome evaluation: A review

Animal Models and Experimental Medicine, EarlyView.
Rodents are the preeminent stroke model species. Large animal models exist too, but are poorly standardized. Ischemic and hemorrhagic experimental models are available, with the intraluminal filament model being predominant. Outcomes are evaluated via quantifying subjects' sensorimotor impairment, cognitive memory faculties, degree of cellular ...
Solsa Cariba, Helen M. Atkinson, Anthony K. C. Chan   +2 more
wiley   +1 more source

Cerebral No‐Reflow after Thrombectomy: International Delphi Consensus on Definition and Imaging Assessment

Annals of Neurology, EarlyView.
Background The operational definition and imaging assessment of the no‐reflow phenomenon, a potential contributor to poor clinical outcome despite successful thrombectomy, remains debated. We aimed to develop expert‐based international consensus on the definition, assessment, and reporting standard of cerebral no‐reflow post‐thrombectomy. Methods Three‐
Adnan Mujanovic, Samantha Rivet, Adrien ter Schiphorst, Jean‐Claude Baron, Johannes Kaesmacher, Felix Ng, Cerebral No‐Reflow Delphi‐Consensus Group, Pooja Khatri, Xin Cheng, Andrea Zini, Maria Hernandez Perez, Ettore Nicolini, Marta Rubiera, Charlotte Rosso, Marie Luby, Victor Del Brutto, Christopher Favilla, Angel Chamorro, Angelika Hoffman, David Liebeskind, Sven P. R. Luijten, Moritz Hernandez Petzsche   +21 more
wiley   +1 more source