Results 51 to 60 of about 2,550,374 (236)

Recurrent high-risk pulmonary thromboembolism treated with repeated thrombolytic therapy could be helpful for certain patients: a case report and review of the literature

open access: yesEuropean Journal of Case Reports in Internal Medicine, 2023
Acute pulmonary thromboembolism (PTE) is considered the third most frequent acute cardiovascular syndrome behind myocardial infarction and stroke, with annual incidence rates ranging from 39 to 115 per 100,000 people and ranking high among the causes of ...
Leila Bigdelu   +2 more
doaj   +1 more source

Initiation of Gabapentin with Opioids and Risk of Respiratory Cardiovascular and Opioid‐Related Adverse Events Following Surgery for Breast Cancer

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Pain is a key determinant of quality‐of‐life following breast cancer surgery, the most common cancer operation in the United States. Gabapentinoids are frequently prescribed for pain management, yet their respiratory, cardiovascular, and opioid‐related adverse effects remain unclear.
Jyun‐Heng Lai   +12 more
wiley   +1 more source

A fibrin targeted molecular imaging evaluation of microvascular no‐reflow in acute ischemic stroke

open access: yesBrain and Behavior, 2022
Objective To investigate the relationship between fibrin deposition and “no‐reflow” within microcirculation after thrombolysis in acute ischemic stroke (AIS).
Xi Chen   +8 more
doaj   +1 more source

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

open access: yesThe Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song   +7 more
wiley   +1 more source

Personification of the approaches to reperfusion therapy of ischemic stroke

open access: yesАнналы клинической и экспериментальной неврологии, 2017
Introduction. Systemic thrombolytic therapy using recombinant tissue plasminogen activator (rtPA) is the gold standard of reperfusion therapy in certainpatients with ischemic stroke during the first 4.5 h after stroke onset. Objective.
Maksim A. Domashenko   +5 more
doaj   +1 more source

Carbon dots as a smart nanoplatform for the blood‐brain barrier penetration and ischemic stroke therapy

open access: yesResponsive Materials, EarlyView.
This review presents the structure and transport routes of the blood‐brain barrier, summarizes the ischemic stroke pathophysiological cascade, and discusses the BBB‐crossing mechanisms and multitarget therapeutic effects of carbon dots, demonstrating their promising theranostic potential for ischemic stroke.
Yanhan Huang   +6 more
wiley   +1 more source

Pharmaceutical Sponsorship Bias Influences Thrombolytic Literature in Acute Ischemic Stroke

open access: yesWestern Journal of Emergency Medicine, 2011
Background: The efficacy of thrombolytic therapy for acute ischemic stroke remains controversial in Emergency Medicine and has not been fully endorsed by either the American College of Emergency Physicians or the American Academy of emergency medicine. A
Ryan P Radecki
doaj  

Half-dose thrombolytic therapy in patients with right heart thrombi

open access: yesJournal of International Medical Research, 2019
The management of floating right heart thrombi (FRHT) in patients with acute pulmonary emboli is controversial. Several recent case series have revealed similar efficacy and better survival rates with systemic thrombolytic therapy than with surgery.
Jamal Moosavi   +10 more
doaj   +1 more source

Multi‐Scale Magnetically Controlled Soft Matter Robots for Tissue Interfacing Applications

open access: yesSmartBot, EarlyView.
Magnetically controlled soft matter robots (MSMRs) integrate remote magnetic control with soft matter adaptability for minimally invasive biomedical tasks at tissue interfaces across multiple scales. This review examines the interaction mechanisms between MSMRs and tissue interfaces, with MSMRs classified into five categories according to their ...
Wenxin Lian   +9 more
wiley   +1 more source

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