Results 71 to 80 of about 38,466 (239)

ZFP36L1 Enhances Microglial Ferroptosis in Ischemic Stroke by Reducing FTO‐Mediated N6‐Methyladenosine Demethylation of ACSL1 mRNA

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Microglia play an important role in ischemic stroke (IS). However, the molecular regulatory mechanisms underlying microglial ferroptosis in IS remain incompletely understood. In this study, blood samples were collected from 20 IS patients and 15 healthy volunteers.
Ai‐Xia Song, Han‐Xu Jin, Yuan‐Xin Sun, Wen‐Hui Kou, Xiao‐Ning Niu, Huan‐Huan Wang, Ting‐Ting Zhong, Ping Gu   +7 more
wiley   +1 more source

Optimising coronary reperfusion in acute myocardial infarction: the role of primary angioplasty

, 2007
PhDThrombolysis remains the predominant reperfusion strategy for ST segment elevation myocardial infarction (STEMI) in the United Kingdom. Although primary angioplasty may offer superior outcomes, the logistics of delivering this therapy in the UK ...
Smith, Elliot J
core  

Orbital and intracranial hemorrhage following thrombolysis: A case report

Journal of Clinical Ophthalmology and Research, 2015
Thrombolytic therapy has been a major advance in the treatment of acute myocardial infarction to achieve coronary reperfusion and improve survival. Bleeding is the most common complication following thrombolytic therapy which can occur spontaneously and ...
Karuppannasamy Divya, Kanagaraju Vikrant, Andavar Raghuram, Tamilmani Yazhini   +3 more
doaj   +1 more source

Preclinical Evaluation of Berry Extracts as a Nutritional Intervention to Alleviate Myocardial Ischemia–Reperfusion Injury and Atherosclerosis Development

Phytotherapy Research, EarlyView.
Schematic representation of the experimental design and the proposed mechanisms underlying the cardioprotective and anti‐atherosclerotic effects of Greek‐derived berry extracts. C57BL/6 mice with WD–induced MS and ApoE−/− mice with atherosclerosis received chronic supplementation with WMex or BBex.
Lydia Symeonidi, Panagiota‐Efstathia Nikolaou, Panagiotis Stathopoulos, Andriana Christodoulou, Alexandra Svouraki, Panagiotis Efentakis, Christina Chania, Angeliki Choustoulaki, Maria Xenaki, Anna Agapaki, Maria Tsoumani, Nikolaos Kostomitsopoulos, Ioulia Tseti, Gemma Vilahur, Alexios‐Leandros Skaltsounis, Ioanna Andreadou   +15 more
wiley   +1 more source

Pulmonary alveolar hemorrhage following thrombolytic therapy

, 2017
Santhosh Narayanan,1 NK Thulaseedharan,1 Gomathy Subramaniam,2 Geetha Panarkandy,1 Narayanan Arathi1 1Department of Medicine, 2Department of Radiodiagnosis, Government Medical College, Kozhikode, Kerala, India Abstract: We report a case of a 58-year-old ...
Subramaniam G, Narayanan S, Panarkandy G, Thulaseedharan NK, Arathi N   +4 more
core  

Intravenous tPA therapy does not worsen acute intracerebral hemorrhage in mice [PDF]

, 2013
Tissue plasminogen activator (tPA) is the only FDA-approved treatment for reperfusing ischemic strokes. But widespread use of tPA is still limited by fears of inadvertently administering tPA in patients with intracerebral hemorrhage (ICH).
Emiri Mandeville, Cianchetti, Flor A., Ken Arai, van Leyen, Klaus, Frieder Schlunk (280822), Eng H. Lo (112154), Kazim Yigitkanli, Chris B Schaffer, Mandeville, Emiri, Yigitkanli, Kazim, Xiaoying Wang, Nathanael L Rosidi, Chris B. Schaffer (155846), Arne Lauer (280824), Fan, Xiang, Eng H Lo, Helmuth Steinmetz (149409), Rosidi, Nathanael L., Xiang Fan (280830), Schlunk, Frieder, Frieder Schlunk, Flor A. Cianchetti (280825), Wang, Xiaoying, Christian Foerch (149410), Flor A Cianchetti, Kazim Yigitkanli (280829), Arai, Ken, Förch, Christian, Leyen, Klaus van, Lo, Eng H., Foerch, Christian, Xiang Fan, Schaffer, Chris B., Ken Arai (280828), Klaus van Leyen, Helmuth Steinmetz, Emiri Mandeville (280827), Steinmetz, Helmuth, Christian Foerch, Lo, Eng, Arne Lauer, Nathanael L. Rosidi (280821), Xiaoying Wang (30853), Klaus van Leyen (280831), Lauer, Arne   +44 more
core   +1 more source

Carotid Endarterectomy in the Acute Period of Ischemic Stroke After Thrombolytic Therapy

Неотложная медицинская помощь
AIM OF STUDY. To study the outcomes, complications and risk factors of CEA surgery in patients after thrombolytic therapy.MATERIAL AND METHODS. The results of treatment of patients after carotid endarterectomy in the acute period of ischemic acute ...
D. А. Nekrasov, D. Ya. Ziyarova, A. V. Gavrilenko   +2 more
doaj   +1 more source

Activatable smart contrast agents for photoacoustic imaging

Smart Molecules, EarlyView.
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh, Jihye Lee, Suyoung Park, Juyoung Yoon, Won Jong Kim, Chulhong Kim   +5 more
wiley   +1 more source

Thrombolytic therapy for prosthetic cardiac valve thrombosis

, 1987
To determine the efficacy and safety of thrombolytic therapy for prosthetic valve thrombosis, a composite series of 41 patients who received either streptokinase or urokinase intravenously for this disorder were analyzed.
Singh, Arun K., Kurzrok, Steven, Most, Albert S., Williams, David O.   +3 more
core   +1 more source

Staging concept for aging management: Definition, mechanism, and coping strategies

VIEW, EarlyView.
We divided the overall aging stage into “pre‐aging”, “aging compensation”, and “aging disability”. For each stage, we delineate the clinical presentations, biological phenomena, theoretical underpinnings, and key management priorities. Abstract Aging, as a gradual and largely irreversible biological process, characterized by declining organismal ...
Zhonghan Wang, Shixian Liu, Shangyu Du, Xiangran Cui, Bo Chao, Minglei Liu, Minfei Wu   +6 more
wiley   +1 more source