Results 71 to 80 of about 32,411 (197)

COMPARATIVE EFFICACY OF ANTICOAGULANT AND THROMBOLYTIC THERAPY IN PATIENTS WITH ACUTE THROMBOSIS OF THE INFERIOR VENA CAVA

open access: yesJournal of V. N. Karazin Kharkiv National University: Series Medicine, 2013
138 patients with thrombosis in the system of the inferior vena cava was examined and treated. Thrombolytic therapy (TLT) as a basic method of treatment was used in 52 (37,7 %) patients.
D. V. Okley
doaj  

Modern methods for the estimation of thrombolysis efficiency in patients with myocardial infraredness with the rise of ST

open access: yesЛечащий Врач, 2021
This article presents a literature review dedicated to modern methods of noninvasive evaluation of efficacy of thrombolytic therapy in patients with ST-segment elevation in myocardial infarction. D-dimer as a probable marker of myocardial reperfusion and
E. M. Podgornaya   +3 more
doaj  

Mitochondrial oxidative stress, calcium and dynamics in cardiac ischaemia‐reperfusion injury

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Heart attack causes ischaemia–reperfusion injury in cardiomyocytes. Mitochondria generate reactive oxygen species (ROS), leading to oxidative stress. High levels of mitochondrial calcium (Ca2+) activate the mitochondrial permeability transition pore (mPTP), and excess ROS levels can lower the Ca2+ required to activate the mPTP ...
Emily Rozich   +5 more
wiley   +1 more source

Management of Acute Superior Mesenteric Artery Occlusion by Thrombolytic Therapy

open access: yesCase Reports in Gastroenterology, 2009
Acute occlusion of the superior mesenteric artery (SMA) causes extensive bowel necrosis, resulting in a poor prognosis with an extremely high mortality rate. An 82-year-old woman was admitted to our hospital with the complaint of abdominal pain.
Shinichi Okamura   +13 more
doaj   +1 more source

The origin of thrombolytic therapy

open access: yesJournal of the American College of Cardiology, 1989
The origin of thrombolytic therapy is briefly reviewed. It began 40 years ago with the demonstration that the injection into patients of a partially purified activator of the native plasminogen-plasmin enzyme system was capable of dissolving clotted blood and fibrinous loculations in the chest.
openaire   +2 more sources

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

open access: yesFEBS Open Bio, Volume 16, Issue 8, Page 1452-1458, August 2026.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková   +3 more
wiley   +1 more source

Heterogeneity in plasma p‐tau217 response and its association with cognitive trajectories under lecanemab treatment

open access: yesAlzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Plasma phosphorylated tau 217 (p‐tau217) is a promising biomarker for monitoring treatment response in Alzheimer's disease (AD), but its longitudinal dynamics and clinical relevance remain unclear. METHODS In this prospective real‐world study, 153 patients with early AD receiving lecanemab were analyzed.
Sung Hoon Kang   +13 more
wiley   +1 more source

CLINICAL RESULTS OF THROMBOLYTIC THERAPY WITH ALTEPLASE AND TENECTEPLASE IN PATIENTS WITH MYOCARDIAL INFARCTION

open access: yesРациональная фармакотерапия в кардиологии, 2015
Aim. To evaluate the clinical results of thrombolytic therapy with thrombolytics (alteplase, tenecteplase) in patients with ST segment elevation myocardial infarction (STEMI). Material and methods.
L. A. Bondarenko   +4 more
doaj   +1 more source

Hematoma Interleukin‐1 Receptor Antagonist Concentrations Predict Long‐Term Outcome in Acute Human Intracerebral Hemorrhage

open access: yesAnnals of Neurology, Volume 100, Issue 2, Page 345-360, August 2026.
Objectives The interleukin (IL)‐1, IL‐6, and C‐reactive protein (CRP) pathway is central to the immune response after intracerebral hemorrhage (ICH). We tested for associations between hematoma and plasma cytokine concentrations and patient outcomes in Minimally Invasive Surgery Plus Rt‐PA for ICH Evacuation Phase III (MISTIE III) participants ...
Adrian R. Parry‐Jones   +54 more
wiley   +1 more source

Intravenous Thrombolysis Combined With Endovascular Treatment Versus Endovascular Treatment Alone in Acute Ischemic Stroke due to Tandem Lesions: A Systematic Review and Meta‐Analysis

open access: yesBrain and Behavior, Volume 16, Issue 8, August 2026.
Our systematic review and meta‐analysis evaluate whether intravenous thrombolysis (IVT) plus endovascular therapy (EVT) outperforms EVT alone in patients with acute ischemic stroke due to tandem lesions. Pooled data from nine studies involving 1756 patients demonstrate that IVT + EVT is associated with significantly higher rates of functional ...
Wenqian Wei   +8 more
wiley   +1 more source

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