Results 91 to 100 of about 38,466 (239)
Tailored thrombolytic therapy. A perspective
, 1993 BACKGROUND. In contrast with current standard regimens, it seems more appropriate to tailor thrombolytic therapy to individual patient characteristics. A proposed model for such tailored therapy is based on individual assessment of benefits and risks of ...
Simoons, M.L. (Maarten) +1 more
core
The rationale for thrombolytic therapy [PDF]
European Heart Journal, 1996 Substantial progress has been made toward understanding the pathophysiological processes that lead to acute myocardial infarction. Research has shown that the mechanism of infarction is the rupture of an atherosclerotic plaque with a subsequent thrombogenic response from exposed subendothelial tissue, leading to additional or complete obstruction of ...
openaire +2 more sources
Лечащий Врач, 2021 This article presents a literature review dedicated to modern methods of noninvasive evaluation of efficacy of thrombolytic therapy in patients with ST-segment elevation in myocardial infarction. D-dimer as a probable marker of myocardial reperfusion and
E. M. Podgornaya +3 more
doaj
Management of Acute Superior Mesenteric Artery Occlusion by Thrombolytic Therapy
Case Reports in Gastroenterology, 2009 Acute occlusion of the superior mesenteric artery (SMA) causes extensive bowel necrosis, resulting in a poor prognosis with an extremely high mortality rate. An 82-year-old woman was admitted to our hospital with the complaint of abdominal pain.
Shinichi Okamura +13 more
doaj +1 more source
Ischemia–Reperfusion Injury: Molecular Mechanisms and Therapeutic Interventions
MedComm, Volume 7, Issue 7, July 2026.Multiorgan ischemia–reperfusion injury begins with ischemia‐induced ATP depletion and ionic imbalance, followed by reperfusion‐triggered mitochondrial ROS/RNS bursts, regulated cell death, and DAMP release. Sterile inflammation converges on endothelial–immune–coagulation crosstalk, where NETs drive immunothrombosis, no‐reflow, and remote organ injury ...
Peng An +4 more
wiley +1 more source
Intracranial hemorrhage after thrombolytic therapy. A perspective
, 1993 The most feared complication of thrombolytic therapy is intracranial hemorrhage. Nevertheless, the benefits of thrombolysis far outweight the potential hazzards of a cerebral bleed.
Boersma, E. +3 more
core +1 more source
British Journal of Clinical Pharmacology, Volume 92, Issue 6, Page 1787-1808, June 2026.Aims Prescribing is a complex, essential skill that doctors must acquire to practice medicine safely and effectively. The British Pharmacological Society has historically provided a core curriculum to guide clinical pharmacology and prescribing education in UK medical schools.
Dagan O. Lonsdale +5 more
wiley +1 more source
APOE and Cerebral Microbleeds: Insights Into Causal Proteins and Therapeutic Targets
Brain and Behavior, Volume 16, Issue 6, June 2026.This study identifies APOE as a key causal protein for cerebral microbleeds (CMBs). By integrating Mendelian randomization (MR) and colocalization analysis of the plasma proteome from UKB‐PPP and deCODE datasets, we provide genetic evidence that circulating APOE levels are causally linked to CMB susceptibility. Furthermore, protein–protein interaction (
Lei Yang +8 more
wiley +1 more source
, 2010 Background: Reactive oxygen species have been implicated in the pathogenesis of ischemic and reperfusion injury. In the current work we have measured malondialdehyde (MDA), total thiols, total CK, CK-MB and AST in ECG proven acute myocardial infarction ...
Mungli, Prakash +5 more
core
Thrombolytic therapy in acute ischemic stroke. A Danish pilot study.
, 1993 In a feasibility and safety study of thrombolytic therapy in acute ischemic stroke, we explored the usefulness of measurements of regional cerebral blood flow.
T S Olsen +9 more
core +1 more source