Results 81 to 90 of about 2,550,374 (236)
ABSTRACT Background Pediatric thromboembolism is increasingly encountered in critical care. Systemic thrombolysis with tissue plasminogen activator (tPA) facilitates vessel or valve patency, yet pediatric‐specific protocols remain undefined, and safety concerns persist. Objective To evaluate the efficacy and safety of a tailored, prolonged systemic tPA
Eran Shostak +5 more
wiley +1 more source
Cost-utility analysis of thrombolytic therapy
An analysis of the cost-effectiveness of thrombolytic therapy was performed, based on 3- to 5-year follow-up data, from 533 patients randomized to receive conventional therapy or intracoronary streptokinase.
Vos, J. (Jeroen) +2 more
core +1 more source
Neutrophil Extracellular Traps Block Fibrinolysis in Ischemic Stroke
Objectives Intravenous thrombolysis (IVT) failure in acute ischemic stroke (AIS) is frequent, but its causes remain elusive. We investigated whether biologically relevant intrathrombus concentrations of tissue plasminogen activator (tPA) were achieved in failed IVT and whether neutrophil extracellular traps (NETs) contributed to this therapeutic ...
Mialitiana Solo Nomenjanahary +21 more
wiley +1 more source
Thrombolytic therapy in pulmonary embolism. [PDF]
Massive pulmonary embolism carries a high mortality. Potential treatment includes anticoagulation, thrombolytic therapy and embolectomy. We report a case of deep vein thrombosis leading to progressive massive pulmonary embolism despite appropriate ...
Hayes, J, Nagi, D
core
Update on Thrombolytic Therapy in Acute Pulmonary Thromboembolism
Thrombolytic treatment accelerates the dissolution of thrombus in acute pulmonary thromboembolism (PTE) and is potentially a lifesaving treatment. High-risk PTE is the clearest indication for this therapy, and its use in intermediate-risk cases is still ...
YILMAZEL UÇAR, Elif, Elif Yilmazel Ucar
core +1 more source
Neurodegenerative diseases share convergent risk architectures and pathological mechanisms, yet diverge in selective vulnerability, clinical presentation, and therapeutic responsiveness. This review integrates cross‐disease epidemiology, pathophysiology, diagnosis, and treatment, highlighting the transition from symptomatic care toward biomarker‐guided
Zimeng He +4 more
wiley +1 more source
Objective:To analyze the status quo of knowledge,attitude and practice of community population on thrombolytic therapy of ischemic stroke patients in Beijing,so that community residents knew the importance of early treatment of ischemic stroke.Methods:A ...
曹闻亚 +4 more
doaj
Debate: Should the elderly receive thrombolytic therapy or primary angioplasty?
Thrombolysis and primary angioplasty are both recommended reperfusion strategies for elderly patients presenting with myocardial infarction (MI). Primary angioplasty is most beneficial in high-risk patients. While the elderly have a high absolute risk of
White Harvey D
doaj +1 more source
The origin of thrombolytic therapy
The origin of thrombolytic therapy is briefly reviewed. It began 40 years ago with the demonstration that the injection into patients of a partially purified activator of the native plasminogen-plasmin enzyme system was capable of dissolving clotted blood and fibrinous loculations in the chest.
openaire +2 more sources
ABSTRACT Introduction Pediatric ambulatory surgery is the dominant model of surgical care in the U.S. and has impacted the practice of regional anesthesia (RA). Pediatric RA's use has expanded as a supplement to general anesthesia with the introduction of ultrasound.
David E. Liston +5 more
wiley +1 more source

