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Thrombophilia in pregnancy: a systematic review [PDF]
British Journal of Haematology, 2006 Growing evidence suggests that thrombophilia is associated with venous thromboembolism (VTE) and adverse pregnancy outcomes. However, methodological limitations have made it difficult to obtain a clear overview of the overall risks.
Olivia Wu
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Current Opinion in Hematology, 1999
Thrombophilia is now considered a multicausal disease, with an interplay of acquired and genetic risk factors. Recent studies have shown that patients with the 20210 A prothrombin mutation display remarkably similar characteristics compared with patients with Factor V Leiden mutation.
M V, Huisman, F, Rosendaal
openaire +2 more sources
Thrombophilia is now considered a multicausal disease, with an interplay of acquired and genetic risk factors. Recent studies have shown that patients with the 20210 A prothrombin mutation display remarkably similar characteristics compared with patients with Factor V Leiden mutation.
M V, Huisman, F, Rosendaal
openaire +2 more sources
Seminars in Thrombosis and Hemostasis, 2007
This issue of Seminars in Thrombosis and Hemostasis is dedicated to inherited thrombophilia. The various clinical manifestations and implications for testing are discussed in different articles. Furthermore, animal models that are being used to study thrombophilia are discussed.
Middeldorp, Saskia, Levi, Marcel
openaire +2 more sources
This issue of Seminars in Thrombosis and Hemostasis is dedicated to inherited thrombophilia. The various clinical manifestations and implications for testing are discussed in different articles. Furthermore, animal models that are being used to study thrombophilia are discussed.
Middeldorp, Saskia, Levi, Marcel
openaire +2 more sources
Obstetrics and Gynecology Clinics of North America, 2006
Many inherited thrombophilias have been detected and the pathophysiologic insight has increased tremendously during the last decades. Despite, however, the overwhelming observational evidence on the association between inherited thrombophilia and several women's health issues, including VTE, thus far the implications for clinical practice are uncertain.
Coppens, Michiel +2 more
openaire +3 more sources
Many inherited thrombophilias have been detected and the pathophysiologic insight has increased tremendously during the last decades. Despite, however, the overwhelming observational evidence on the association between inherited thrombophilia and several women's health issues, including VTE, thus far the implications for clinical practice are uncertain.
Coppens, Michiel +2 more
openaire +3 more sources
Journal of Pharmacy Practice, 2014
Although controversial, screening for thrombophilia has become common. Testing for antiphospholipid antibodies is indicated in order to guide treatment decisions if there is clinical suspicion for antiphospholipid syndrome. The utility of identifying other thrombophilias in symptomatic venous thromboembolism (VTE) is questionable, as the risk of ...
Lori B, Hornsby +4 more
openaire +2 more sources
Although controversial, screening for thrombophilia has become common. Testing for antiphospholipid antibodies is indicated in order to guide treatment decisions if there is clinical suspicion for antiphospholipid syndrome. The utility of identifying other thrombophilias in symptomatic venous thromboembolism (VTE) is questionable, as the risk of ...
Lori B, Hornsby +4 more
openaire +2 more sources
Hämostaseologie, 2008
SummaryVenous thromboembolism (VTE) is a rare disease that is being increasingly diagnosed and recognized in paediatrics in the past decade, usually as a secondary complication of primary severe underlying diseases. Apart from acquired thrombophilic risk factors, such as lupus anticoagulants, inherited thrombophilias (IT) have been established as risk ...
U, Nowak-Göttl +3 more
openaire +2 more sources
SummaryVenous thromboembolism (VTE) is a rare disease that is being increasingly diagnosed and recognized in paediatrics in the past decade, usually as a secondary complication of primary severe underlying diseases. Apart from acquired thrombophilic risk factors, such as lupus anticoagulants, inherited thrombophilias (IT) have been established as risk ...
U, Nowak-Göttl +3 more
openaire +2 more sources
Expert Review of Cardiovascular Therapy, 2007
The physiological changes that occur during pregnancy create a hypercoagulable milieu. This hypercoagulable state is thought to be protective, especially at the time of labor, preventing excessive hemorrhage. The presence of hereditary or acquired causes of thrombophilia during pregnancy tilts the balance in favor of unwanted venous thromboembolism and
Mrinal M, Patnaik +2 more
openaire +2 more sources
The physiological changes that occur during pregnancy create a hypercoagulable milieu. This hypercoagulable state is thought to be protective, especially at the time of labor, preventing excessive hemorrhage. The presence of hereditary or acquired causes of thrombophilia during pregnancy tilts the balance in favor of unwanted venous thromboembolism and
Mrinal M, Patnaik +2 more
openaire +2 more sources