Post-viral idiopathic purpura fulminans is associated with inherited thrombophilia and anti-cardiolipin antibodies [PDF]
Frontiers in Pediatrics, 2023 IntroductionIdiopathic purpura fulminans (IPF) is a rare and severe coagulation disorder, associated with transient anti-protein S (anti-PS) antibodies in the context of post-viral infection such as varicella.
A. Theron +15 more
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Primary prophylaxis of venous thromboembolic disease with direct oral anticoagulants in patients with severe inherited thrombophilia [PDF]
Research and Practice in Thrombosis and Haemostasis, 2021 Direct oral anticoagulants (DOACs) are widely used in several indications, but data on their efficacy and safety in individuals affected by severe inherited thrombophilia, yet without any personal history of thrombosis, is lacking.
Evelien Krumb, Cedric Hermans
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Impact of Inherited Thrombophilia on Pregnancy Complications and the Role of Low-Molecular-Weight Heparin Therapy: A Case–Control Study [PDF]
MedicinaBackground and Objectives: Inherited thrombophilia (IT) increases the risk of adverse pregnancy outcomes, but the benefit of low-molecular-weight heparin (LMWH) prophylaxis remains debated.
Dragana Maglic +5 more
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Recommendations from guidelines for the prevention of venous thromboembolism in pregnant women with inherited thrombophilia [PDF]
Archives of Gynecology and ObstetricsWomen with inherited thrombophilia represent more than 15% of the pregnant population. 20–50% of pregnancy-related venous thromboembolism (VTE) is associated with at least one inherited thrombophilia, which increases the risk of VTE up to 40-fold ...
Werner Rath +2 more
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The Contribution of Inherited Thrombophilia to Venous Thromboembolism in Cancer Patients [PDF]
Clinical and Applied Thrombosis/HemostasisAlthough the relationship between venous thromboembolism (VTE) and cancer has been a subject of study, knowledge of the contribution of thrombophilia to thrombosis in patients with cancer is still very limited.
José Costa MD, António Araújo MD, PhD
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Reported Prevalence of Inherited Thrombophilia in Pregnancy: Impact of Cohort Selection on Screening Implications—A Systematic Review [PDF]
DiagnosticsBackground/Objectives: Inherited thrombophilia (IT) has been extensively investigated as a potential contributor to adverse pregnancy outcomes; however, reported prevalence varies widely across studies. This systematic review aimed to evaluate how cohort
Maria Fulina +6 more
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Inherited thrombophilia and portal vein thrombosis in cirrhosis: A systematic review and meta‐analysis [PDF]
Research and Practice in Thrombosis and Haemostasis, 2019 Background Portal vein thrombosis (PVT) is common in cirrhosis. PVT is associated with high morbidity and mortality. Individual reports suggest that PVT occurs more frequently in patients with cirrhosis and inherited thrombophilia.
Steven D. Ma +5 more
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Direct Oral Anticoagulants in Patients With Inherited Thrombophilia and Venous Thromboembolism: A Prospective Cohort Study [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020 Background In this prospective cohort study, we aimed to evaluate the efficacy and safety of direct oral anticoagulants (DOACs) versus heparin/vitamin K antagonists for the treatment of venous thromboembolism (VTE) in patients with inherited ...
Elena Campello +10 more
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Risks of anticoagulation discontinuation after first venous thromboembolism in inherited thrombophilia: a long-term cohort study [PDF]
Research and Practice in Thrombosis and HaemostasisBackground: Inherited thrombophilia confers high venous thromboembolism (VTE) recurrence risk, and guidelines generally recommend indefinite anticoagulation after first VTE.
Sang-A Kim +6 more
doaj +2 more sources
Inherited Thrombophilia in Early-Onset Carotid Stenosis: A Comparative Study of Dissection, Atherosclerosis, Fibromuscular Dysplasia, and Other Etiologies [PDF]
Clinical and Applied Thrombosis/HemostasisBackground Carotid artery stenosis is a recognized cause of ischemic stroke in older adults but is rare in individuals under 50, where distinct etiologies such as dissection, fibromuscular dysplasia (FMD), or genetic predispositions are often implicated.
Ebru Marzioglu Ozdemir MD +1 more
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