Results 1 to 10 of about 194,689 (201)

Primary prophylaxis of venous thromboembolic disease with direct oral anticoagulants in patients with severe inherited thrombophilia [PDF]

Research and Practice in Thrombosis and Haemostasis, 2021
Direct oral anticoagulants (DOACs) are widely used in several indications, but data on their efficacy and safety in individuals affected by severe inherited thrombophilia, yet without any personal history of thrombosis, is lacking.
Evelien Krumb, Cedric Hermans
doaj   +3 more sources

Post-viral idiopathic purpura fulminans is associated with inherited thrombophilia and anti-cardiolipin antibodies [PDF]

Frontiers in Pediatrics, 2023
IntroductionIdiopathic purpura fulminans (IPF) is a rare and severe coagulation disorder, associated with transient anti-protein S (anti-PS) antibodies in the context of post-viral infection such as varicella.
A. Theron, A. Theron, A. Theron, S. Ayadi, E. Boissier, O. Dautremay, O. Dautremay, J.-F. Schved, N. Sirvent, I. Diaz, G. Captier, G. Captier, C. Biron-Andreani, C. Biron-Andreani, E. Jeziorski, E. Jeziorski   +15 more
doaj   +2 more sources

Recommendations from guidelines for the prevention of venous thromboembolism in pregnant women with inherited thrombophilia [PDF]

Archives of Gynecology and Obstetrics
Women with inherited thrombophilia represent more than 15% of the pregnant population. 20–50% of pregnancy-related venous thromboembolism (VTE) is associated with at least one inherited thrombophilia, which increases the risk of VTE up to 40-fold ...
Werner Rath, Panagiotis Tsikouras, Ulrich Pecks   +2 more
doaj   +2 more sources

Impact of Inherited Thrombophilia on Pregnancy Complications and the Role of Low-Molecular-Weight Heparin Therapy: A Case–Control Study [PDF]

Medicina
Background and Objectives: Inherited thrombophilia (IT) increases the risk of adverse pregnancy outcomes, but the benefit of low-molecular-weight heparin (LMWH) prophylaxis remains debated.
Dragana Maglic, Vesna Mandic-Markovic, Zeljko Mikovic, Rastko Maglic, Radomir Anicic, Milica Mandic   +5 more
doaj   +2 more sources

The Contribution of Inherited Thrombophilia to Venous Thromboembolism in Cancer Patients [PDF]

Clinical and Applied Thrombosis/Hemostasis
Although the relationship between venous thromboembolism (VTE) and cancer has been a subject of study, knowledge of the contribution of thrombophilia to thrombosis in patients with cancer is still very limited.
José Costa MD, António Araújo MD, PhD
doaj   +2 more sources

Reported Prevalence of Inherited Thrombophilia in Pregnancy: Impact of Cohort Selection on Screening Implications—A Systematic Review [PDF]

Diagnostics
Background/Objectives: Inherited thrombophilia (IT) has been extensively investigated as a potential contributor to adverse pregnancy outcomes; however, reported prevalence varies widely across studies. This systematic review aimed to evaluate how cohort
Maria Fulina, Lucian Șerbănescu, Georgeta-Camelia Cozaru, Elena Danteș, Elena Dumea, Eugenia-Alina Radu, Elena Mocanu   +6 more
doaj   +2 more sources

Inherited thrombophilia and portal vein thrombosis in cirrhosis: A systematic review and meta‐analysis [PDF]

Research and Practice in Thrombosis and Haemostasis, 2019
Background Portal vein thrombosis (PVT) is common in cirrhosis. PVT is associated with high morbidity and mortality. Individual reports suggest that PVT occurs more frequently in patients with cirrhosis and inherited thrombophilia.
Steven D. Ma, Jennifer Wang, Dmitri Bezinover, Zakiyah Kadry, Patrick G. Northup, Jonathan G. Stine   +5 more
doaj   +2 more sources

Risks of anticoagulation discontinuation after first venous thromboembolism in inherited thrombophilia: a long-term cohort study [PDF]

Research and Practice in Thrombosis and Haemostasis
Background: Inherited thrombophilia confers high venous thromboembolism (VTE) recurrence risk, and guidelines generally recommend indefinite anticoagulation after first VTE.
Sang-A Kim, Sin Young Park, Ji Yun Lee, Junshik Hong, Sang-Hoon Na, Jeong-Ok Lee, Soo-Mee Bang   +6 more
doaj   +2 more sources

Direct Oral Anticoagulants in Patients With Inherited Thrombophilia and Venous Thromboembolism: A Prospective Cohort Study [PDF]

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background In this prospective cohort study, we aimed to evaluate the efficacy and safety of direct oral anticoagulants (DOACs) versus heparin/vitamin K antagonists for the treatment of venous thromboembolism (VTE) in patients with inherited ...
Elena Campello, Luca Spiezia, Chiara Simion, Daniela Tormene, Giuseppe Camporese, Fabio Dalla Valle, Anna Poretto, Cristiana Bulato, Sabrina Gavasso, Claudia Maria Radu, Paolo Simioni   +10 more
doaj   +2 more sources

Management of inherited thrombophilia in pregnancy [PDF]

Women's Health, 2016
Adverse pregnancy outcomes, such as pregnancy loss and pre-eclampsia, are associated with thrombotic mechanisms and thrombophilia. Antithrombotic interventions, particularly low-molecular-weight heparin, have been investigated in women identified by previous pregnancy outcome; however, the results have been inconsistent.
Laura Ormesher, Louise Simcox, Ian A Greer   +2 more
exaly   +4 more sources