Post-viral idiopathic purpura fulminans is associated with inherited thrombophilia and anti-cardiolipin antibodies [PDF]
IntroductionIdiopathic purpura fulminans (IPF) is a rare and severe coagulation disorder, associated with transient anti-protein S (anti-PS) antibodies in the context of post-viral infection such as varicella.
A. Theron +15 more
doaj +2 more sources
Primary prophylaxis of venous thromboembolic disease with direct oral anticoagulants in patients with severe inherited thrombophilia [PDF]
Direct oral anticoagulants (DOACs) are widely used in several indications, but data on their efficacy and safety in individuals affected by severe inherited thrombophilia, yet without any personal history of thrombosis, is lacking.
Evelien Krumb, Cedric Hermans
doaj +2 more sources
Impact of Inherited Thrombophilia on Pregnancy Complications and the Role of Low-Molecular-Weight Heparin Therapy: A Case–Control Study [PDF]
Background and Objectives: Inherited thrombophilia (IT) increases the risk of adverse pregnancy outcomes, but the benefit of low-molecular-weight heparin (LMWH) prophylaxis remains debated.
Dragana Maglic +5 more
doaj +2 more sources
Recommendations from guidelines for the prevention of venous thromboembolism in pregnant women with inherited thrombophilia [PDF]
Women with inherited thrombophilia represent more than 15% of the pregnant population. 20–50% of pregnancy-related venous thromboembolism (VTE) is associated with at least one inherited thrombophilia, which increases the risk of VTE up to 40-fold ...
Werner Rath +2 more
doaj +2 more sources
The Contribution of Inherited Thrombophilia to Venous Thromboembolism in Cancer Patients [PDF]
Although the relationship between venous thromboembolism (VTE) and cancer has been a subject of study, knowledge of the contribution of thrombophilia to thrombosis in patients with cancer is still very limited.
José Costa MD, António Araújo MD, PhD
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Case report: Clinical profile, molecular genetics, and neuroimaging findings presenting in a patient with Kearns-Sayre syndrome associated with inherited thrombophilia [PDF]
BackgroundKearns-Sayre syndrome (KSS) is classified as one of the mitochondrial DNA (mtDNA) deletion syndromes with multisystemic involvement. Additionally, the negative prognosis is associated with inherited thrombophilia, which includes the presence of
Anca Elena Gogu +8 more
doaj +2 more sources
Inherited thrombophilia and portal vein thrombosis in cirrhosis: A systematic review and meta‐analysis [PDF]
Background Portal vein thrombosis (PVT) is common in cirrhosis. PVT is associated with high morbidity and mortality. Individual reports suggest that PVT occurs more frequently in patients with cirrhosis and inherited thrombophilia.
Steven D. Ma +5 more
doaj +2 more sources
Direct Oral Anticoagulants in Patients With Inherited Thrombophilia and Venous Thromboembolism: A Prospective Cohort Study [PDF]
Background In this prospective cohort study, we aimed to evaluate the efficacy and safety of direct oral anticoagulants (DOACs) versus heparin/vitamin K antagonists for the treatment of venous thromboembolism (VTE) in patients with inherited ...
Elena Campello +10 more
doaj +2 more sources
Inherited Thrombophilia in Early-Onset Carotid Stenosis: A Comparative Study of Dissection, Atherosclerosis, Fibromuscular Dysplasia, and Other Etiologies [PDF]
Background Carotid artery stenosis is a recognized cause of ischemic stroke in older adults but is rare in individuals under 50, where distinct etiologies such as dissection, fibromuscular dysplasia (FMD), or genetic predispositions are often implicated.
Ebru Marzioglu Ozdemir MD +1 more
doaj +2 more sources
Common Risk Factors Add to Inherited Thrombophilia to Predict Venous Thromboembolism Risk in Families [PDF]
The clinical venous thromboembolism (VTE) pattern often shows wide heterogeneity within relatives of a VTE-affected family, although they carry the same thrombophilia defect.
Pierre Suchon +10 more
doaj +2 more sources

