Results 31 to 40 of about 5,800 (169)

Family history and inherited thrombophilia [PDF]

Journal of Thrombosis and Haemostasis, 2006
It is a common belief that patients with venous thrombosis and a positive family history for venous thromboembolism (VTE) have an increased likelihood of having an inherited thrombophilic defect.We analyzed the relation between family history, qualified with three different methods, and thrombophilic status in 314 patients with proven VTE.
van Sluis, G. L., Söhne, M., El Kheir, D. Y., Tanck, M. W., Gerdes, V. E. A., Büller, H. R.   +5 more
openaire   +2 more sources

Management of pregnancy and labor in female with combination of homozygous Leiden and heterozygous prothrombin G20210A mutations

Акушерство, гинекология и репродукция, 2020
Here we describe a clinical case of successfully managed pregnancy and labor in female with multigenic thrombophilia (combination of homozygous Leiden and heterozygous prothrombin G20210A mutations) associated with high risk of thrombosis by using proper
M. O. Arslanbekova, J. Kh. Khizroeva
doaj   +1 more source

Complement inhibitory proteins expression in placentas of thrombophilic women Complement inhibitory proteins expression in placentas of thrombophilic women

Folia Histochemica et Cytobiologica, 2012
Factors controlling complement activation appear to exert a protective effect on pregnancy. This is<br />particularly important in women with thrombophilia.
Przemysław Krzysztof Wirstlein, Piotr Jasiński, Marcin Rajewski, Tomasz Goździewicz, Jana Skrzypczak   +4 more
doaj   +1 more source

Evaluation of thrombophilia testing in the inpatient setting: A single institution retrospective review.

PLoS ONE, 2021
BackgroundThrombophilia workup is typically inappropriate in the inpatient setting as testing may be skewed by anticoagulation, acute thrombosis, or acute illness.ObjectiveTo determine adherence of inpatient thrombophilia testing with institutional ...
Chun Ting Siu, Zachary Wolfe, Martin DelaTorre, Erafat Rehim, Robert Decker, Kathryn Zaffiri, Bradley Lash   +6 more
doaj   +1 more source

Structural Control of Stromal‐Immune Coupling by COL24A1 Underlies Pregnancy Maintenance

Advanced Science, EarlyView.
COL24A1 emerges as a collagen‐associated regulator of maternal‐fetal interface homeostasis. Its deficiency promotes a maladaptive TIMP1‐high stromal state, impaired ECM turnover, collagen accumulation, and stromal–immune dysregulation, contributing to pregnancy loss.
Teng Wu, Lingling Xie, Wenyi Liu, Hanjie Mo, Chengshu Xie, Jing Tang, Zhaorui Wang, Peixuan Lan, Jianping Zhang, Jie Gao, Qionglan Tang, Chunwei Cao, Hui Chen   +12 more
wiley   +1 more source

Cardiovascular toxicity induced by TKIs in patients with chronic myeloid leukaemia: Are women and men different?

ESC Heart Failure, Volume 12, Issue 2, Page 1447-1454, April 2025.
This study analyzes 148 patients (66 women and 82 men) with chronic myeloid leukemia treated with tyrosine kinase inhibitors, focusing on cardiovascular adverse events. The risk assessment, performed using the HFA/ICOS score, reveals sex‐specific differences: venous thrombosis is more common in women, while arterial thrombosis predominates in men.
Cristina Madaudo, Daniela Di Lisi, Antonio Cannatà, Federica Manfrè, Celeste Vullo, Marco Santoro, Ciro Botta, Salvatrice Mancuso, Sergio Siragusa, Alfredo Ruggero Galassi, Giuseppina Novo   +10 more
wiley   +1 more source

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Is retinal vein occlusion an underrecognized paraneoplastic sentinel of lymphoma? A systematic review and meta‐analysis of ocular–haematological interactions

Acta Ophthalmologica, EarlyView.
Abstract Topic This systematic review and meta‐analysis evaluated the association between retinal vein occlusion (RVO) and lymphoma across two complementary evidence components: a qualitative clinical synthesis of RVO occurring in patients with lymphoma and a quantitative synthesis of subsequent cancer outcomes in patients with RVO. For the qualitative
Kai‐Yang Chen, Hoi‐Chun Chan, Chi‐Ming Chan   +2 more
wiley   +1 more source

The role of d-dimer as first marker of thrombophilia in women affected by sterility: implications in pathophysiology and diagnosis of thrombophilia induced sterility

Journal of Translational Medicine, 2004
Background D-dimer is considered a marker of hypercoagulable state and of endogenous fibrinolysis, so increased d-dimer is detectable in patients affected by thrombosis.
Di Micco Pierpaolo, D'Uva Maristella, Strina Ida, Mollo Antonio, Amato Valeria, Niglio Alferio, De Placido Giuseppe   +6 more
doaj   +1 more source