Results 51 to 60 of about 5,800 (169)
Haemophilia, EarlyView.ABSTRACT Background Hereditary factor X (FX) deficiency is a rare autosomal recessive bleeding disorder for which individualized pharmacokinetic (PK) assessment can support optimized prophylactic management. The WAPPS‐Hemo platform enables population pharmacokinetic (PopPK) individualized PK predictions based on sparse sampling.
Dagmar M. Hajducek +4 more
wiley +1 more source
Shared Decision‐Making in Haemophilia Involves More Treatment Differentiators in 2026
Haemophilia, EarlyView.ABSTRACT Introduction Shared decision‐making regarding treatment choice in haemophilia care has become increasingly more complex and essential due to the availability of several innovative therapeutics that are characterized by their own advantages and limitations, which need to be tailored to individual patient needs.
Quentin Van Thillo +2 more
wiley +1 more source
Arthritis Care &Research, Volume 78, Issue 11, Page 1691-1700, November 2026.Objective The aim of this study was to evaluate the sensitivity of the 2023 American College of Rheumatology (ACR)/EULAR classification criteria for antiphospholipid syndrome (APS) in a real‐world cohort of women diagnosed with primary obstetric APS (oAPS) and to assess their ability to identify patients at risk of future pregnancy complications ...
Francesca Ruffilli +10 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACTAdipsic hypernatremia is a rare disorder characterized by impaired thirst perception despite severe hyperosmolality, most commonly resulting from hypothalamic dysfunction. Hyperosmolar hyperglycemic state (HHS) may further aggravate dehydration and electrolyte imbalance, increasing the risk of neurologic injury, acute kidney injury (AKI), and ...
Mahshad Ghoddusi +6 more
wiley +1 more source
Haematologica, 2001 BACKGROUND AND OBJECTIVES: Oral contraceptives (OC) and inherited thrombophilia are well-known risk factors associated with venous thromboembolism (VTE). However, there are only few studies on the risk of VTE in women with inherited thrombophilia who use
A Santamaria +8 more
doaj
Subclinical Cerebral Lesions in Migraine: A Proof‐of‐Concept Study on Platelet Aggregation
European Journal of Neurology, Volume 33, Issue 11, November 2026.We assessed platelet aggregation in patients with migraine (n = 34) with or without cerebral white‐matter lesions (WMLs) versus matched controls (n = 34), with WMLs volume quantified by MRI (mm3). Aggregation to ADP, collagen, epinephrine, and arachidonic acid was measured; epinephrine‐induced aggregation at 1.25–2.5 μM was overall lower in migraine ...
Ilaria Maestrini +10 more
wiley +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Congenital uterine anomalies are an important and potentially treatable contributor to recurrent pregnancy loss (RPL). The septate uterus is the commonest Müllerian anomaly linked to first‐trimester loss, and its differentiation from the benign arcuate uterus is essential for management, yet imaging modalities may disagree.
Iftekhar Ahmed Sakib +2 more
wiley +1 more source
Inherited thrombophilia and venous thromboembolism: testing rules in clinical practice
Российский кардиологический журнал, 2020 Testing for inherited thrombophilia in patients with venous thromboembolism is one of the most common genetic testing options prescribed by clinicians. Despite the large evidence base for the relationship of hereditary hemostasis disorders with the risk ...
I. V. Zotova, D. A. Zateyshchikov
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 10, October 2026.ABSTRACT Managing thrombosis in patients with bleeding disorders requires careful assessment of thromboembolic and bleeding risks, tailoring antithrombotic treatment in terms of type, dose, and duration, and considering the need for replacement therapy based on individual factor levels and bleeding history.
Synnøve Gjelsten Mortensen +4 more
wiley +1 more source