Results 51 to 60 of about 6,414 (212)

Gout in pregnancy: Obstetric and neonatal outcomes

International Journal of Gynecology &Obstetrics, Volume 169, Issue 1, Page 349-355, April 2025.
Abstract Objective The pregnancy, delivery, and neonatal outcomes of pregnancies complicated by gout have yet to be evaluated in a population‐based study. We sought to evaluate the obstetric and neonatal outcomes in pregnant patients with gout using a national population database.
Sam Amar, Ahmad Badeghiesh, Haitham Baghlaf, Michael H. Dahan   +3 more
wiley   +1 more source

Genetic mutations among a group of patients with unstimulated thrombosis in Sulaymaniyah Northeastern Iraq

Iraqi Journal of Hematology, 2020
BACKGROUND: Thromboembolism is a complex disease caused by different acquired and inherited factors. The common mutations including Factor V leiden (FVL), prothrombin (PTG), and methylenetetrahydrofolate reductase (MTHFR) are important inherited causes ...
Ali Ibrahim Mohammed
doaj   +1 more source

Maternal and neonatal outcomes in Gaza amid armed hostilities in 2025

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective This study documents facility‐based maternal, obstetric, and neonatal outcomes and associated conflict‐related exposures and living conditions among pregnancy‐related encounters at Al‐Helou Maternity Hospital in Gaza from late April to early September 2025, with a small number of additional encounters recorded at Al‐Shifa Medical ...
Shaymaa Abuhaiba, Younis Elijla, Aya El‐Dadah, Othman Nassar, Meran Abu‐Sultan, Maysaa Almasry, Hebatallah Alkhatib, Mahmoud Alsady, Amir Mahdi Ghafarian, Muath Alsarafandi, Lina Abumughessib, Arham Ali, Yassar Arain, Abeerah Muhammad, Belal Aldabbour, Shayan Ali, Bilal Irfan   +16 more
wiley   +1 more source

Inherited thrombophilia in pediatric venous thromboembolic disease: Why and who to test [PDF]

, 2017
Venous thromboembolic disease in childhood is a multifactorial disease. Risk factors include acquired clinical risk factors such as a central venous catheter and underlying disease and inherited thrombophilia.
C. Heleen van Ommen, Ommen, C.H. (Heleen) van, Ulrike Nowak-Göttl, Nowak-Göttl, U. (Ulrike)   +3 more
core   +1 more source

Decidual macrophage‐mediated ferroptosis in trophoblasts leads to recurrent spontaneous abortion

iMeta, EarlyView.
Decidual macrophages from recurrent spontaneous abortion (RSA) patients promote trophoblast ferroptosis and impair trophoblast cell function. Mechanistically, the CXCL2/NF‐κB/HMOX1 axis mediates this effect. Conversely, trophoblasts co‐cultured with RSA decidual macrophages induce pro‐inflammatory macrophage polarization through IL‐6/JAK2/STAT3 ...
Xin Chen, Xueqin Ma, Pengcheng Pang, Heng Zhou, Ruohan Li, Yan He, Yan Zhang, Jing Yang, Qianlin Song, Qingsong Ye   +9 more
wiley   +1 more source

Placental Dysfunction and Congenital Heart Disease: Investigating the Placenta‐Heart Axis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective Concurrent development of the placenta and heart during early gestation suggests a shared biological basis for the co‐occurrence of abnormal placentation and congenital heart disease (CHD). This study investigated the association between placental vascular pathology and CHD type.
Natalie Lanners, Sarah U. Morton, Katherine Le, Steffy Blanco, Sara Mansoorshahi, Chrystalle Katte Carreon, Christina Ronai, Louise Wilkins‐Haug, Vidhya Annavajjhala, Jacqueline G. Parchem, Tina O. Findley   +10 more
wiley   +1 more source

Indications and Efficacy of Progestogen‐Monotherapy as Menopause Hormone Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Menopausal hormone therapy (MHT) remains the most effective treatment for vasomotor symptoms (VMS) and other manifestations of menopause; however, its use is limited in women with contraindications to oestrogen. Progestogen monotherapy, though historically underutilized, represents a viable alternative in this population. This narrative review
Chloe Thomas, Olivia Carere, Lauren Clarfield, Michelle Jacobson   +3 more
wiley   +1 more source

Update on Menopause Hormone Therapy; Current Indications and Unanswered Questions

Clinical Endocrinology, EarlyView.
ABSTRACT Objective To provide clinicians involved in managing menopause with a summary of current evidence surrounding menopause hormone therapy (MHT). Design The authors evaluate and synthesize existing pooled evidence relating to MHT's clinical indications, efficacy, and safety and explore the limitations of existing data. Patients The review focuses
Annice Mukherjee, Susan R. Davis
wiley   +1 more source

Contrasting Approaches in the Implementation of GRADE Methodology in Guidelines for Haemophilia and Von Willebrand Disease

Haemophilia, EarlyView.
ABSTRACT Introduction The 2024 ISTH clinical practice guideline (CPG) for treatment of congenital haemophilia, the NBDF‐McMaster Guideline on Care Models for Haemophilia Management, and ASH ISTH NBDF WFH guidelines on the diagnosis and management of VWD all utilised GRADE methodology.
Mark W. Skinner, Manuela Albisetti, Jesús Ardila, Jan Astermark, Jan Blatny, Manuel Carcao, Pratima Chowdary, Nathan T. Connell, Miguel Crato, Yesim Dargaud, Roseline d'Oiron, Amy L. Dunn, Miguel A. Escobar, Carmen Escuriola‐Ettingshausen, Emna Gouider, Annie Harroche, Cedric Hermans, Victor Jimenez‐Yuste, Radoslaw Kaczmarek, Gili Kenet, Liane Khoo, Robert Klamroth, Florian Langer, David Lillicrap, Johnny Mahlangu, Christoph Male, Tadashi Matsushita, Sandrine Meunier, Wolfgang Miesbach, Beatrice Nolan, Johannes Oldenburg, Brian O'Mahony, Margareth Ozelo, Glenn F. Pierce, Gloria Ramos, Michael Recht, Olivia Romero‐Lux, Dawn Rotellini, Rita C. Santoro, Tammuella C. Singleton, Alok Srivastava, Sophie Susen, Kate Talks, Huyen Tran, Leonard A. Valentino, Jerzy Windyga, Renchi Yang, Maria Elisa Mancuso, also on behalf of AICE, AHAD‐AP, AHCDC, ATHN, CLAHT, EHC, French CRH & MHEMO, HTCCNC, NBDF, PEDNET, UKHCDO, WFH   +59 more
wiley   +1 more source

Inherited Thrombophilia and Pregnancy Complications: Should We Test?

, 2018
Recurrent miscarriages and pregnancy-related complications cause significant stress to couples looking for successful pregnancy outcome as well as to health care professionals.
Deepa Arachchillage, Mike Makris
core   +1 more source